Skip to main content
Log in

Blood biochemical alterations during recovery from competitive marathon running

  • Published:
European Journal of Applied Physiology and Occupational Physiology Aims and scope Submit manuscript

Summary

The occurrence of possible prolonged alterations in plasma levels of cortisol, epinephrine, norepinephrine, selected energy metabolites, and water and electrolyte balance was assessed in six highly trained male marathon runners by measuring blood biochemical constituents on the 10th day before and for the three days following the running of a marathon. Post-race changes in hemoglobin, hematocrit, and protein levels indicated that a hemodilution had occurred, possibly as a result of elevated sodium levels. Epinephrine remained elevated until the second day. Cortisol was depressed on the first and third post-race days while variable levels were observed on the second day. No prolonged alterations were noted in norepinephrine, FFA, glycerol, triglycerides, glucose, lactate, and pyruvate.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Blake, J. B., Larrabee, R. C.: Observations upon long-distance runners. Boston med. surg. J. 148, 195–206 (1903)

    Google Scholar 

  2. Campuzano, H. C., Wilkerson, J. E., Raven, P. B., Schabram, T., Horvath, S. M.: A radioimmunoassay for cortisol in humans. Biochem. Med. 7, 350–362 (1973)

    Google Scholar 

  3. Campuzano, H. C., Wilkerson, J. E., Horvath, S. M.: Fluorometric analysis of epinephrine and norepinephrine. Analyt. Biochem. 64, 578–587 (1975)

    Google Scholar 

  4. Crosby, W. H., Furth, F. W.: A modification of the benzidine method for measurement of hemoglobin in plasma and urine. Blood 11, 380–383 (1956)

    Google Scholar 

  5. Dill, D. B., Costill, D. L.: Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J. appl. Physiol. 37, 247–248 (1974)

    Google Scholar 

  6. Dunlop, J. C., Paton, D. N., Stockman, R., Maccadam, I.: On the influence of muscular exercise, sweating, and massage on the metabolism. J. Physiol. 22, 68–91 (1897)

    Google Scholar 

  7. Maron, M. B., Horvath, S. M., Wilkerson, J. E.: Acute blood biochemical alteration in response to marathon running. Europ. J. appl. Physiol. 34, 173–182 (1975)

    Google Scholar 

  8. Moore, F. D.: Homeostasis: Bodily changes in trauma and surgery. In: Textbook of surgery, 10th (ed. L. Davis) pp. 26–64. Philadelphia: W. B. Saunders 1972

    Google Scholar 

  9. Myhre, L. G., Brown, D. K., Hall, F. G., Dill, D. B.: The use of carbon monoxide and T-1824 for determining blood volume. Clin. Chem. 14, 1197–1205 (1968)

    Google Scholar 

  10. Newmark, S. R., Himathongkam, T., Martin, R. P., Cooper, K. H., Rose, L. I.: Adrenocortical response to marathon running. J. clin. Endocr. 42, 393–394 (1976)

    Google Scholar 

  11. Novak, M.: Colorimetric ultramicro method for the determination of free fatty acids. J. Lipid Res. 6, 431–433 (1965)

    Google Scholar 

  12. O'Hanlon, J. F., Jr., Campuzano, H. C., Horvath, S. M.: A fluorometric assay for subnanogram concentrations of adrenaline and noradrenaline in plasma. Analyt. Biochem. 34, 568–581 (1970)

    Google Scholar 

  13. Riley, W. J., Pyke, F. S., Roberts, A. D., England, J. F.: The effect of long-distance running on some biochemical variables. Clin. chim. Acta 65, 83–89 (1975)

    Google Scholar 

  14. Sevitt, S.: Reactions to injuries and burns and their clinical importance. London: Heinemann 1974

    Google Scholar 

  15. Ström, G.: The influence of anoxia on lactate utilization in man after prolonged muscular work. Acta physiol. scand. 17, 440–451 (1949)

    Google Scholar 

  16. Viru, A., Körge, P.: Metabolic processes and adrenalcortical activity during marathon races. Int. Z. angew. Physiol. 29, 173–183 (1971)

    Google Scholar 

  17. Winer, B. J.: Statistical principles in experimental design, 2nd ed. New York: McGraw-Hill 1971

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

This work was supported in part by the Air Force Office of Scientific Research, Air Force Systems Command, Grant AFOSR 73-2455

Rights and permissions

Reprints and permissions

About this article

Cite this article

Maron, M.B., Horvath, S.M. & Wilkerson, J.E. Blood biochemical alterations during recovery from competitive marathon running. Europ. J. Appl. Physiol. 36, 231–238 (1977). https://doi.org/10.1007/BF00423048

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00423048

Key words

Navigation