Abstract
• Background: The association of butterfly-shaped pigment dystrophy of the fovea, an uncommon inherited macular disease, with subretinal neovascularization has rarely been reported in the literature. • Case report: We describe the clinical history of a patient affected with butterfly-shaped pigment dystrophy of the fovea, myopia, and optic nerve head dysplasia. She was followed up for 23 years. During the course of the disease, bilateral subretinal neovascularization in the macular area occurred. Fluorescein angiography confirmed the diagnosis. Recently, indocyanine green (CG) videoangiography was also performed. Because of the bilateral subfoveal localization no laser treatment was advised. • Discussion: Usually, good visual acuity is maintained in this uncommon inherited macular disease. However, acute visual loss can be caused by the ingrowth of subretinal new vessels. Therefore, if visual acuity decreases or metamorphopsia develops in these patients, careful biomicroscopic examination and fluorescein/ICG angiography is advisable.
References
Aandekerk AL, Deutman AF, van Nouhuys E (1980) Format-filled detail photographs with the Kowa RC-W retinal camera. Ophthalmologica, Basel 181: 1–6
Avetisov ES, Savitskaya NF (1977) Some features of ocular microcirculation in myopia. Ann Ophthalmol 9: 1261–1264
Bloom SM (1994) Peripapillary subretinal neovascularization associated with coloboma of the optic nerve. (letter) Arch Ophthalmol 112: 154
Burgess D (1981) Subretinal neovascularization in a pattern dystrophy of the retinal pigment epithelium. Retina 1: 151–155
Caldwell RB, McLaughlin BJ, Boykins LG (1982) Intramembrane changes in retinal pigment epithelial cell junction of the dystrophic rat retina. Invest Ophthalmol Vis Sci 23: 305–318
Cardillo Piccolino F, Zingirian M (1988) Pattern dystrophy of the retinal pigment epithelium with vitelliform macular lesion: evolution in ten years. Int Ophthalmol 11: 207–217
Chopard A (1976) Reticular dystrophy of retina. Br J Ophthalmol 60: 342–344
Curtin BJ (1963) The pathogenesis of congenital myopia: a study of 66 cases. Arch Ophthalmol 69: 166–173
Dailey JR, Cantore WA, Gardner TW (1993) Peripapillary choroidal neovascular membrane associated with an optic nerve coloboma. (letter) Arch Ophthalmol 111:441–442
Deutman AF, Rümke AML (1969) Reticular dystrophy of the reginal pigment epithelium. Arch Ophthalmol 82: 4–9
Deutman AF, van Blommestein JDA, Henkes HE, Waardenburg PJ, Sollevan-van Driest E (1970) Butterfly-shaped pigment dystrophy of the fovea. Arch Ophthalmol 83: 558–569
Gass JMD (1974) A clinicopathologic study of a peculiar foveomacular dystrophy. Trans Am Ophthalmol Soc 72: 139–156
Giuffrè G (1988) Autosomal dominant pattern dystrophy of the retinal pigment epithelium: intrafamilial variability. Retina 8: 169–173
Giuffrè G, Lodato G (1986) Vitelliform dystrophy and pattern dystrophy of the retinal pigment epithelium: a concomitant presence in a family. Br J Ophthalmol 70: 526–532
Grossniklaus HE, Hutchinson AK, Capone A, Woolfson J, Lambert HM (1994) Clinicopathologic features of surgically excised choroidal neovascular membranes. Ophthalmology 101: 1099–1111
Gutman I, Walsh JB, Henkind P (1982) Vitelliform macular dystrophy and butterflyshaped epithelial dystrophy: a continuum? Br J Ophthalmol 66: 170–173
Hsieh RC, Fine BS, Lyons JS (1977) Patterned dystrophies of the retinal pigment epithelium. Arch Ophthalmol 95: 429–435
Kingham JD, Fenzl RE, Willerson D, Aaberg TM (1978) Reticular dystrophy of the retinal pigment epithelium: a clinical and electrophysiologic study of three generations. Arch Ophthalmol 96: 1177–1184
Lodato G, Giuffrè G (1985) Associations inusuelles dans les dystrophies en réseau. J Fr Ophthalmol 8: 147–154
Meija JR, Gieser RG (1981) Sporadic butterfly macular dystrophy. Ann Ophthalmol 13: 1253–1254
Nichols BE, Drack AV, Vandenburgh K, Kimura AE, Sheffield VC, Stone EM (1993) A 2 base pair deletion in the RDS gene associated with butterfly-shaped pigment dystrophy of the fovea. Hum Mol Genet 2: 601–603
Noble KG, Carr RE (1982) Pathologic myopia. Ophthalmology 89: 1099–1100
Shiono T, Ishikawa A, Hara S, Tamai M (1990) Pattern dystrophy of the retinal pigment epithelium. Retina 10: 251–254
Sjögren H (1950) Dystrophia reticularis laminae pigmentosae retinae. Acta Ophthalmol 28: 279–295
Slezak H, Hommer K (1969) Fundus pulverulentus. Graefes Arch Klin Exp Ophthalmol 178: 177–182
Thomas MA, Dickinson JD, Melberg NS, Ibanez HE, Dhaliwal RS (1994) Visual results after surgical removal of subfoveal choroidal neovascular membranes. Ophthalmology 101: 1384–1396
Watzke RC, Folk JC, Lang RM (1982) Pattern dystrophy of the retinal pigment epithelium. Ophthalmology 89: 1400–1406
Yedavally S, Frank RN (1993) Peripapillary subretinal neovascularization associated with coloboma of the optic nerve. Arch Ophthalmol 111: 552–553
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Marano, F., Deutman, A.F. & Aandekerk, A.L. Butterfly-shaped pigment dystrophy of the fovea associated with subretinal neovascularization. Graefe's Arch Clin Exp Ophthalmol 234, 270–274 (1996). https://doi.org/10.1007/BF00430421
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DOI: https://doi.org/10.1007/BF00430421