Abstract
A variety of bacterial functions are encoded on plasmids, extrachromosomal elements. Examples of plasmid-borne functions are antibiotic production and resistance, degradation of recalcitrant chemicals, virulence factors, and plant symbiotic properties. Several transport systems with diverse functions have recently been found to be carried on plasmids. These systems serve to either accumulate or extrude a compound from a cell. The focus of this review is to present a survey on several of these novel plasmid-borne transport systems emphasizing functions, components, and molecular genetics.
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Actis, L. A., Potter, S., and Crosa, J. H. (1988).J. Biol. Chem. 263, 2853–2866.
Actis, L. A., Fish, W., Crosa, J. H., Kellerman, K., Ellenberger, S. R., Hauser, F. H., and Luher-Saunders, J. (1986).J. Bacteriol. 167, 57–65.
Barrineau, P., Gilbert, P., Jackson, W. J., Jones, C. S., and Summers, A. O. (1984).J. Mol. Appl. Genet. 2, 601–619.
Binderieff, A., Braun, V., and Hantke, K. (1982).J. Bacteriol. 150, 1472–1475.
Bopp, L. H., Chakrabaraty, A. M., and Ehrlich, H. L. (1983).J. Bacteriol. 155, 1105–1109.
Bopp, L. H., and Ehrlich, H. L. (1988).Arch. Microbiol. 150, 426–431.
Braun, V. (1981).FEMS Microbiol. Lett. 140, 225–228.
Carbonetti, N. H. and Williams, P. H. (1984).Infect. Immun. 46, 7–12.
Cervantes, C., Ohtake, H., and Silver, S. (1988).Annu. Meet. Am. Soc. Microbiol. Abstracts, p. 180.
Chen, C.-M., Misra, T., Silver, S., and Rosen, B. P. (1986).J. Biol. Chem. 261, 15030–15038.
Chen, C.-M., Mobley, H. L. T., and Rosen, B. P. (1985).J. Bacteriol. 161, 758–763.
Cotter, C. M., Trevors, J. T., and Gadd, G. M. (1987).FEMS Microbiol. Lett. 48, 299–303.
Curiale, M. S., McMurry, L. M., and Levy, S. B. (1984).J. Bacteriol. 157, 211–217.
Eberz, G., Eitinger, T., and Friedrich, B. (1989).J. Bacteriol. 171, 1340–1345.
Ebner, R., and Lengeler, J. W. (1988).Microbiol. 2, 9–17.
Eckert, B., and Beck, C. F. (1989).J. Biol. Chem. 264 11663–11670.
Foster, T. J., Nakahara, H., Weiss, A. A., and Silver, S. (1979).J. Bacteriol. 140, 167–181.
Grewal, K. K., Warner, P. J., and Williams, P. H. (1982).FEBS Lett. 140, 27–30.
Hedges, R. W., and Baumberg, S. (1973).J. Bacteriol. 115, 459–460.
Hickman, R. K., and Levy, S. B. (1988).J. Bacteriol. 170, 1715–1720.
Higgins, C. F. (1989).Nature (London)341, 103.
Higgins, C. F., Hiles, I. D., Salmond, G. P. C., Gill, D. R., Downie, J. A., Evans, I. J., Holland, I. B., Gray, L., Buckel, S. D., Bell, A. W., and Hermodson, M. A. (1986).Nature (London)323, 448–450.
Higgins, C. F., Hiles, I. D., Whalley, K., and Jamieson, D. J. (1985).EMBO J. 4, 1033–1040.
Hillen, W., and Scollmier, K. (1983).Nucleic Acids Res. 11, 525–539.
Hirato, T., Shinagawa, M., Ishiguro, N., and Sato, G. A. (1984).J. Bacteriol. 160, 421–426.
Horitsu, H., Futo, S., Ozawa, K., and Kawai, K. (1983).Agric. Biol. Chem. 47, 2907–2908.
Hsu, C. M., and Rosen, B. P. (1989a). InHighlights of Modern Biochemistry (Kotyk, A., Skoda, J., Paces, V., and Kostka, V. B., eds.), VSP International Science Publishers, Zeist, pp. 743–751.
Hsu, C. M., and Rosen, B. P. (1989b).J. Biol. Chem. 264, 17349–17354.
Ishiguro, N., and Sato, G. (1979).J. Hyg. 83, 331–344.
Ishiguro, N., and Sato, G. (1985).J. Bacteriol. 164, 977–982.
Ishiguro, N., Oka, C., and Sato, G. (1978).Appl. Environ. Microbiol. 36, 217–222.
Ishiguro, N., Sato, G., and Yoshikawa, M. (1981).J. Bacteriol. 148, 383–385.
Ishiguro, N., Sasatu, N., Misra, T. K., and Silver, S. (1988).Gene 68, 181–192.
Jackson, W. J., and Summers, A. O. (1982).J. Bacteriol. 151, 962–970.
Jobling, M. G., and Ritchie, D. A. (1987).Mol. Gen. Genet. 208, 28–293.
Jobling, M. G., and Ritchie, D. A. (1988).Gene ???.
Jones, I. G., and Midgley, M. (1985).FEMS Microbiol. Lett. 28 355–358.
Kaneko, M., Yamaguchi, A., and Sawai, T. (1985).FEBS Lett. 193, 194–198.
Karkaria, C. E. and Rosen, B. P. (1990).J. Biol. Chem. 265, 7832–7836.
Kaur, P., and Vadehra, D. V. (1986).Antimicrob. Agents Chemother. 29, 165–167.
Klock, G. B., Unger, B., Gatz, C., Hillen, W., Altenbuchner, J., Schmid, K., and Schmitt, R. (1985).J. Bacteriol. 161, 326–332.
Lengeler, J., Mayer, R., and Schmid, K. (1982).J. Bacteriol. 151, 468–471.
Levy, S. B. (1984). InAntimicrobial Drug Resistance, Academic Press, New York, pp. 191–240.
Levy, S. B., and McMurry, L. (1974).Biochem. Biophys. Res. Commun. 56, 1060–1068.
Mergeay, M. D., Nies, D., Schlegel, H. G., Gertis, J., Chalres, I., and Grizsegemvan, F. (1985).J. Bacteriol. 162, 328–334.
Marshall, B., Morrissey, S., Flynn, P., and Levy, S. B. (1986).Gene 50, 11–117.
McMurry, L., Petrucci, P., and Levy, S. B. (1980).Proc. Natl. Acad. Sci. USA 77, 3974–3977.
Midgley, M. (1986).J. Gen. Microbiol. 132, 3187–3193.
Misra, T. K., Brown, N. L., Fritzinger, D. C., Pridmore, R. D., Barnes, R. W., Haberstroh, L., and Silver, S. (1984).Proc. Natl. Acad. Sci. USA 81, 5975–5979.
Mobley, H. L. T., and Rosen, B. P. (1982).Proc. Natl. Acad. Sci. USA 79, 6119–6122.
Mobley, H. L. T., Chen, C.-M., Silver, S., and Rosen, B. P. (1983).Mol. Gen. Genet. 191 421–426.
Mobley, H. L. T., and Summers, A. O. (1987). InIon Transport in Prokaryotes (Rosen, B., and Silver, S., eds.), Academic Press, New York, pp. 305–326.
Nakahara, H., Silver, S., Miki, T., and Rownd, R. H. (1979).J. Bacteriol. 140, 161–166.
NiBhriain, N., and Foster, T. J. (1986).Gene 42, 323–330.
Nies, A., Nies, D., and Silver, S. (1989a).J. Bacteriol. 171, 5065–5070.
Nies, D. and Silver, S. (1989).J. Bacteriol. 171, 896–900.
Nies, D. H., Nies, A., Chu, L., and Silver, S. (1989b).Proc. Natl. Acad. Sci. USA 86, 7351–7355.
Nguyen, T. T., Postle, K., and Bertrand, K. P. (1983).Gene 25, 83–92.
Novick, R. P., and Roth, C. (1986).J. Bacteriol. 95, 1335–1342.
Nucifora, G., Chu, L., Misra, T. K., and Silver, S. (1989).Proc. Natl. Acad. Sci. USA 86, 3544–3548.
Ohtake, H., Cervantes, C., and Silver, S. (1987).J. Bacteriol. 169, 3853–3856.
Owolabi, J. B., and Rosen, B. P. (1990).J. Bacteriol. 172, 2367–2371.
Pedersen, P. L., and Carafoli, E. (1987).Trends Biochem. Sci. 12, 146–150.
Reynolds, C. H., and Silver, S. (1983).J. Bacteriol. 156, 1019–1024.
Riordan, J. R., Rommens, J. M., Kerem, B., Alon, N., Rozmahel, R., Grzelczak, Z., Zielenski, J., Lok, S., Plavsic, N., Chou, J.-L., Drumm, M. L., Iannuzzi, M. C., Collins, F. S., and Tsui, L.-C. (1989).Nature (London)245, 1066–1073.
Rosen, B. P., and Borbolla, M. G. (1984).Biochem. Biophys. Res. Commun. 124, 760–765.
Rosen, B. P. Weigel, U., Karkaria, C., and Gangola, P. (1988).J. Biol. Chem. 263, 3067–3070.
Rosen, B. P., Hsu, C. M., Karkaria, C. E., Owolabi, J. B., and Tisa, L. S. (1989).Phil. Trans. R. Soc. London, in press.
Rouch, D., Camarkis, J., Lee, B. T. O., and Luke, R. K. J. (1985).J. Gen. Microbiol. 131, 939–943.
San Francisco, M. J. D., Hope, C. L., Owolabi, J. B., Tisa, L. S., and Rosen, B. P. (1990).Nucl. Acid Res. 18, 619–624.
San Francisco, M. J. D., Tisa, L. S., and Rosen, B. P. (1989).Mol. Microbiol. 3, 15–21.
Sasatsu, M., Misra, T., Chu, L. Laddaga, R., and Silver, S. (1985).J. Bacteriol. 164, 983–993.
Schmid, K., Schupfner, M., and Schmitt, R. (1982).J. Bacteriol. 151, 68–76.
Schmid, K., Ebner, R., Altenbuchner, J., Schmitt, R., and Lengeler, J. W. (1988).Mol. Microbiol. 2, 1–8.
Sensfuss, C., and Schlegel, H. G., (1988).FEMS Microbiol. Lett. 55, 295–298.
Siddiqui, R., Benthin, K., and Schlegel, H. G. (1989).J. Bacteriol. 171, 5071–5078.
Siddiqui, R., and Schlegel, H. G. (1987).FEBS Microbiol. Lett. 43, 9–13.
Siddiqui, R., Schlegel, H. G., and Meyer, M. (1988).J. Bacteriol. 170, 4188–4193.
Silver, S., Budd, K., Leahy, K. M., Shaw, W. V., Hammond, D., Novick, R. P., Willsky, G. R., Malamy, M. H., and Rosenberg, H. (1981).J. Bacteriol. 146, 983–996.
Silver, S. and Keach, D. (1982).Proc. Natl. Acad. Sci. USA 79 611–6118.
Silver, S., and Misra, T. K. (1988).Annu. Rev. Microbiol. 42, 717–743.
Starodub, M. E., and Trevors, J. T. (1989).J. Med. Microbiol. 29, 101–110.
Summers, A. O., and Sugarman, L. I. (1974).J. Bacteriol. 119, 242–249.
Tennent, J. M., Lyon, B. R., Gillespie, M. T., May, J. W., and Skurray, R. A. (1985).Antimicrob. Agents Chemother. 27, 79–83.
Tennent, J. M., Lyon, B. R., Midgley, M., Jones, I. G., Purewal, A. S., and Skurray, R. A. (1989).J. Gen. Microbiol. 135, 1–10.
Tisa, L. S., and Rosen, B. P. (1990).J. Biol. Chem.,265, 190–194.
Tolmasky, M. E., Actis, L. A., and Crosa, J. H. (1988).J. Bacteriol. 170 1913–1919.
Trevors, J. T. (1987).Microbiol. Sci. 4, 29–31.
Trevors, J. T., Oddie, K. M., and Belliveau, B. H. (1985).FEMS Microbiol. Rev. 32, 39–54.
Tynecka, Z., Gos, Z., and Zajac, J. (1981a).J. Bacteriol. 147 305–312.
Tynecka, Z., Gos, Z., and Zajac, J. (1981b).J. Bacteriol. 147 313–319.
Unger, B., Klock, G., and Hillen, W. (1984).Nucleic Acids Res. 12, 7693–7703.
Walker, J. E., Saraste, N., Runswick, M. J., and Gay, N. J. (1982).EMBO J. 1, 945–951.
Walters, M. A., Potter, S. A., and Crosa, J. H. (1983).J. Bacteriol. 156 880–887.
Walters, M. A., Bindereis, A., Neilands, J. B., and Crosa, J. H. (1984).Infect. Immun. 43, 765–767.
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Tisa, L.S., Rosen, B.P. Transport systems encoded by bacterial plasmids. J Bioenerg Biomembr 22, 493–507 (1990). https://doi.org/10.1007/BF00762959
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DOI: https://doi.org/10.1007/BF00762959