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Effect of dieldrin on the stability of lysosomes in the rat liver

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Summary

The effect of dieldrin on the bound and free activity of cathepsin, acid ribonuclease, acid phosphatase and aryl sulphatase has been investigated. Administration of dieldrin increased the activity of free cathepsin, acid ribonuclease, and acid phosphatase in rat liver whereas it did not affect the activity of aryl sulphatase. This indicates that dieldrin labilizes the lysosomes.

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Author notes

  1. F. A. Siddiqui

    Present address: Department of Experimental Therapeutics, Rosewell Park Memorial Institute, 666, Elm Street, 14263, Buffalo, New York, USA

Authors and Affiliations

  1. Department of Biochemistry Vallabhbhai Patel Chest Institute, University of Delhi, 110007, Delhi, India

    K. K. Kohli, F. A. Siddiqui & T. A. Venkitasubramanian

Authors
  1. K. K. Kohli
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  2. F. A. Siddiqui
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  3. T. A. Venkitasubramanian
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Additional information

Taken in part from a thesis submitted by KKK to the Faculty of Medical Sciencs, University of Delhi for the degree of Doctor of Philosophy, May 1976.

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Kohli, K.K., Siddiqui, F.A. & Venkitasubramanian, T.A. Effect of dieldrin on the stability of lysosomes in the rat liver. Bull. Environ. Contam. Toxicol. 18, 617–623 (1977). https://doi.org/10.1007/BF01684009

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  • DOI: https://doi.org/10.1007/BF01684009

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