Skip to main content
Log in

Metabolic alterations in liver and testes of adult and newborn rats following cadmium administration

  • Published:
Bulletin of Environmental Contamination and Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Braasch W, Gudbjarnason S, Puri PS, Ravens KG and Bing RJ (1968) Early changes in energy metabolism in the myocardium following acute coronary artery occlusion in anesthetized dogs. Circ Res 23:429–437

    PubMed  Google Scholar 

  • Buckly BJ and Basset DJP (1987) Pulmonary cadmium oxide toxicity in the rat. J Tox Environ Health 21: 233–250

    Google Scholar 

  • Dalvi RR and Robins TJ (1978) Comparative studies on the effects of cadmium, cobalt, lead and selenium on hepatic microsomal monooxygenase enzymes and glutathione levels in mice. J Environ Pathol Toxicol 1:601–607

    PubMed  Google Scholar 

  • Goering PL and Klaasen CD (1984) Zinc induced tolerance to cadmium hepatotoxicity. Toxicol Appl Pharmacol 74: 299–304

    PubMed  Google Scholar 

  • Goering PL and Klaasen CD (1984a) Resistance to cadmium induced hepatotoxicity in immature rats. Toxicol Appl Pharmacol 74:321–329

    PubMed  Google Scholar 

  • Grose EC, Richards JH, Jaskot RH, Menache MG, Graham JA and Dauterman WC (1987) A comparative study of the effects of inhaled cadmium chloride and cadmium oxide: Pulmonary response. J Toxicol Environ Health 21:219–232

    PubMed  Google Scholar 

  • Gunn SA, Gould TC and Anderson AD (1961) Zinc protection against cadmium injury to rat testis. Arch Pathol 71:274–281

    PubMed  Google Scholar 

  • Harkonen M and Kormano M (1970) Acute cadmium induced changes in the energy metabolism of the rat testis. J Reprod Fert 21:221–226

    Google Scholar 

  • Kello D and Kostial K (1974) Influnce of age on absorption of cadmium from the gastrointestinal tract of rats. In Proc Ist Congress of Yugoslav Toxicological Society 1:15–16

    Google Scholar 

  • Klimczak J, Wisniewska-Knypl JM and Kolakowski J (1984) Stimulation of lipid peroxidation and heme oxygenase activity with inhibition of cyt. P-450 monooxygenase in liver of rats repeatedly exposed to cadmium. Toxicology 32:267–273

    PubMed  Google Scholar 

  • Klinberg M (1975) Methods of enzymatic analysis (Ed. H. U. Bergmeyer) Academic Press, New York

    Google Scholar 

  • Lee I and Dixon RL (1973) Effect of cadmium on spermatogenesis studied by velocity sedimentation, cell separation and serial mating. J Pharmacol Exp Therap 187:641–652

    Google Scholar 

  • Lowry OH, Rosebrough NJ, Farr AL and Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265–275

    PubMed  Google Scholar 

  • Muller L (1986) Consequences of cadmium toxicity in rat hepatocytes: Mitochondrial dysfunction and lipid peroxidation. Toxicology 40:285–295

    PubMed  Google Scholar 

  • Marks PA (1966) Methods in enzymology. Vol. IX (Eds Colowick, and Kaplan) Academic Press, New York

    Google Scholar 

  • Parizek J and Zahor Z (1956) Effects of cadmium salts on testicular tissue. Nature 177: 1036–1037

    PubMed  Google Scholar 

  • Parizek J (1957) The destructive effect of cadmium ion on testicular tissue and its prevention by zinc. J Endocrinol 15:55–63

    Google Scholar 

  • Rao PVVP (1983) Effects of intraperitoneal cadmium administration on mitochondrial enzymes in rat tissues. Toxicology 27:81–89

    PubMed  Google Scholar 

  • Vorne M and Arvela P (1971) Effect of carbontetrachloride induced progressive liver damage on drug metabolizing enzymes and cytochrome p-450 in rat liver. Acta Pharmacol Toxicol 29: 417–423

    Google Scholar 

  • Webb M (1972) Protection of zinc against cadmium toxicity. Biochem Pharmacol 21:2767–2771

    PubMed  Google Scholar 

  • Wong KL and Klassen CD (1980) Tissue distribution and retention of cadmium in rats during post-natal development. Minimal role of hepatic metallothionein. Toxicol Appl Pharmacol 53:343–353

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Agarwal, A.K. Metabolic alterations in liver and testes of adult and newborn rats following cadmium administration. Bull. Environ. Contam. Toxicol. 40, 569–575 (1988). https://doi.org/10.1007/BF01688382

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01688382

Keywords

Navigation