Summary
Two pesticides, Karbatox 75 and Unden, were used for the investigation, in daily doses of 20 mg per kg body weight, injected intraperitoneally during a period of 20 days. A comparatively low toxicity of these compounds for mice was ascertained. Among morphological changes were found: hypertrophy of the intestinal epithelium, a decrease in size of liver cells and a significant increase in number of Gomori-positive glia cells, as well as an increase in the volume of cell nuclei in the neurosecretory neurocytes of hypothalamus.
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The authors regard the present paper as an introduction to a more complete cycle of investigations devoted to the problem of pesticide effects.
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Jordan, M., .Srebro, Z., Pierścińska, E. et al. Preliminary observations on the effects on the organs of mice of administering some carbamate pesticides. Bull. Environ. Contam. Toxicol. 14, 205–208 (1975). https://doi.org/10.1007/BF01701315
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DOI: https://doi.org/10.1007/BF01701315