Skip to main content
Log in

Effect of ethionine on hepatic mitochondrial and microsomal calcium uptake

  • Published:
Bulletin of Environmental Contamination and Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Agarwal AK, Mehendale HM, (1986) Effect of chlordecone on carbon tetrachloride induced increase in calcium uptake in isolated perfused rat liver. Toxicol Appl Pharmacol 83:342–348

    PubMed  Google Scholar 

  • Becker GL, Fiscum G, Lehninger AL (1980) Regulations of free Ca++ by liver mitochondria and endoplasmic reticulum. J Biol Chem 255:9009–9012

    PubMed  Google Scholar 

  • Bygrave FL (1978) Mitochondria and control of intracellular calcium. Biol Rev 53:43–79

    PubMed  Google Scholar 

  • Chen WJ, Smuckler EA (1978) Ethionine induced alterations in hepatic microsomal cytochromes in vivo and in vitro: sexual dimorphism. Toxicol Appl Pharmacol 44, 269–276

    PubMed  Google Scholar 

  • Farber E (1963) Ethionine carcinogenesis. Adv Cancer Res 7: 383–474

    Google Scholar 

  • Farber E, Shull KH, Villa-Trevino S, Lombardi B and Thomas M (1964) Biochemical pathology of acute hepatic adenosine triphosphate deficiency. Nature 203: 34–40

    PubMed  Google Scholar 

  • Farber JL, Gill G, Konishi Y (1973) Prevention of galactosamine induced liver cell necrosis by uridine. Amer J Pathol 72: 53–60

    Google Scholar 

  • Farber JL (1981) The role of calcium in cell death. Life Sciences 29:1289–1295

    PubMed  Google Scholar 

  • Harris C, Grady H, Svoboda D (1968) Alterations in pancreatic and hepatic ultra structure following acute cycloheximide intoxication. J Ultrastruc Res 22: 240–251

    Google Scholar 

  • Higgins ES, Friend WH, Rogers KS (1978) Depression by ethionine of phosphorylating oxidation in hepatic mitochondria. Experentia 34: 578–579

    Google Scholar 

  • Kisilevsky R, Wailer L, (1974) A microsomal membrane alteration following ethionine intoxication. Cancer Res 34, 3421–3427

    PubMed  Google Scholar 

  • Kisilevsky R, Weiler L (1976) Microsomal membrane alterations during acute ethionine toxicity and carcinogenesis. Exp Mol Pathol 24: 193–200

    PubMed  Google Scholar 

  • Lowry K, Glende EA, Jr., Recknagel RO (1981) Destruction of liver microsomal calcium purnp activity by carbontetrachloride and bromotrichloromethane. Biochem Pharmacol 30: 135–140

    PubMed  Google Scholar 

  • Lowrey OH, Rosebrough NJ, Farr Al, Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265–275

    PubMed  Google Scholar 

  • Moore L, Davenport GR, Landon EJ (1976) Calcium uptake of a rat liver microsomal subcellular fraction in response to in vivo administration of carbon tetrachloride. J Biol Chem 251:1197–1201

    PubMed  Google Scholar 

  • Robinson DS, Seakins A (1962) The development in the rat of fatty livers associated with reduced plasma lipoprotein synthesis. Biochem Biophys Acta 2: 163–165

    Google Scholar 

  • Schanne FAX, Kane AB, Young EE, Farber JL (1979) Calcium dependence of toxic cell death: A final common pathway. Science 206:700–702

    PubMed  Google Scholar 

  • Verbin RS, Goldblatt PJ, Farber E (1969) The biochemical pathology of inhibition of protein synthesis in vivo. The effects of cycloheximide on hepatic parenchymal cell ultrastructure. Lab Invest 20, 529–536

    PubMed  Google Scholar 

  • Villa-Trevino S, Shull KH, Farber E (1963) The role of adenosine triphosphate deficiency in ethionine induced inhibition of protein systhesis. J Biol Chem 238: 1757–1763

    PubMed  Google Scholar 

  • Villa-Trevino S, Shull KH, and Farber E (1966) The inhibition of liver ribonucleic acid synthesis by ethionine. J Biol Chem 241: 4670–4674

    PubMed  Google Scholar 

  • Wilson JS, Korsten MA, Leo MA, Lieber CS (1936) New technique for the isolation of functional rat pancreatic mitochondria and its application to models of pancreatic injury. J Lab Clin Med 107: 51–58

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Agarwal, A.K., Zinermon, W.D. & Latoni, L. Effect of ethionine on hepatic mitochondrial and microsomal calcium uptake. Bull. Environ. Contam. Toxicol. 40, 287–293 (1988). https://doi.org/10.1007/BF01881053

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01881053

Keywords

Navigation