Summary
Complexes of pyridine-2-carbothioamide with diethyltin dichloride, dibenzyltin dichloride and phenyltin trichloride are described. In each case, the chelating agent is bound to the tin(IV) atom by the pyridine nitrogen and the carbothioamide sulphur, giving support to proposals that certain organotin compounds cause enzyme deactivation via the formation of tin-sulphur bonds.
Similar content being viewed by others
Literatur
G.J. Sutton, Aust. J. Chem.22, 2475 (1969).
G.J. Sutton, Aust. J. Chem.19, 2059 (1966).
H.A. Goodwin, F.E. Smith, E. Konig and G. Ritter, Aust. J. Chem.26, 521 (1973).
F.E. Smith and H.A. Goodwin, Proceedings of the XIX International Conference on Coordination Chemistry, Prague 1978.
C.N.R. Rao and R. Venkataraghavan, Spectrochim. Acta18, 541 (1962).
B. Siugh and K.P. Thakur, J. inorg. nucl. Chem.36, 1735 (1974).
S. Ahrland, J. Chatt and N.R. Davies, Q. Rev. chem. Soc.12, 265 (1958).
R.G. Pearson, J. Am. chem. Soc.85, 353 (1963).
D. Calley, W.L. Guess and J. Autian, J. Pharm. Sci.56, 1267 (1967).
P. Karrer and J. Schukri, Helv. chim. Acta28, 824 (1945).
Author information
Authors and Affiliations
Additional information
Acknowledgment. We thank the Tin Industry (Research and Development) Board, Kuala Lumpur, for financial support.
Rights and permissions
About this article
Cite this article
Smith, F.E., Ee, K.L. Organotin complexes of pyridine-2-carbothioamide. Experientia 36, 391–392 (1980). https://doi.org/10.1007/BF01975104
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01975104