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Hyperlipidemia in guinea pigs induced by chronic vitamin C deficiency

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Abstract

Sixteen weeks of chronic vitamin C deficiency, induced in guinea pigs by restricted vitamin C intake, resulted in a marked increase in the serum total LDL- and VLDL- cholesterol, triglycerides and total lipids. HDL-cholesterol decreased resulting in a highly significant increase in LDL/HDL ratio. The results reconfirm that vitamin C deficiency causes changes in blood lipid profile which could promote atherogenesis.

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Authors and Affiliations

  1. Department of Biochemistry, Dr. S.N. Medical College, Jodhpur

    Praveen Sharma, P. K. Sharma D.Sc. (Professor & Head), J. Pramod, L. K. Kothari, Rashmi Ranka & Sushma Sharma

  2. Department of Biochemistry, J.L.N. Medical College, 305 001, Ajmer

    Praveen Sharma, P. K. Sharma D.Sc. (Professor & Head), J. Pramod, L. K. Kothari, Rashmi Ranka & Sushma Sharma

Authors
  1. Praveen Sharma
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  2. P. K. Sharma D.Sc.
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  3. J. Pramod
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  4. L. K. Kothari
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  5. Rashmi Ranka
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  6. Sushma Sharma
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Sharma, P., Sharma, P.K., Pramod, J. et al. Hyperlipidemia in guinea pigs induced by chronic vitamin C deficiency. Indian J Clin Biochem 4, 62–64 (1989). https://doi.org/10.1007/BF02867654

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  • DOI: https://doi.org/10.1007/BF02867654

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