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Étude de la cohorte nord-finlandaise de 1966: facteurs prédictifs et conséquences de la schizophrénie

Predictors and consequences of schizophrenia in the Northern Finland 1966 birth cohort

  • Épidémiologie Et Facteurs De Risque
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Résumé

Des anomalies de la cognition, de la motricité fine, des émotions et du comportement sont fréquentes chez les enfants apparemment sains, qui plus tard développeront une schizophrénie. Ces éléments suggèrent que certains facteurs favorisants sétablissent bien avant que le diagnostic de psychose ne soit fait. Nous avons tenté de recenser les facteurs contribuant au développement des schizophrénies. Nous nous sommes polarisés sur les facteurs génétiques, les complications de la grossesse et de l’accouchement, le développement précoce, les performances scolaires ainsi que sur les retentissement physique et social. Ce travail est basés sur une revue des travaux scientifiques, des articles publiées et des recherches en cours concernant la cohorte nord-finlandaise de 1966.

Abstract

Subtle motor, emotional, cognitive and behavioural abnormalities are often present in apparently healthy children and adolescents who later develop schizophrenia. This suggests that some aspects of causation are established long before psychosis becomes manifest. We aim to assess the factors contributing to the development of schizophrenia focusing mainly on genetic factors, pregnancy and delivery complications, early development and scholastic performance, as well as later educational, social and health consequences. This is done by reviewing the Northern Finland 1966 Birth Cohort, its scientific activities, publications and work in progress.

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Authors and Affiliations

  1. Département de Psychiatrie, Université de Oulu, France

    Matti Isohanni (Professeur), Irene Isohanni, Hannu Koponen, Erika Lauronen, Sari Lindeman, Jouko Miettunen, Graham Murray, Pirjo Mäki, Kaisa Sarri & Juha Veijola

  2. Départment de Santé Publique et de Médicine Générale, Université de Oulu, France

    Jari Jokelainen & Marjo -Riitta Järvelin

  3. Départment de Radiologie, Université de Oulu, France

    Päivikki Tanskanen

  4. Département de Psychiatrie, Université de Cambridge, France

    Tim Croudace, Peter Jones & Graham Murray

  5. Département d’Épidemiologie et de Santé Publique, Faculté de Médecine, Imperial College, Londres

    Marjo -Riitta Järvelin

Authors
  1. Matti Isohanni
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  2. Tim Croudace
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  3. Irene Isohanni
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  4. Jari Jokelainen
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  6. Marjo -Riitta Järvelin
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  7. Hannu Koponen
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  8. Erika Lauronen
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  10. Jouko Miettunen
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  11. Graham Murray
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  12. Pirjo Mäki
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  13. Kaisa Sarri
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  14. Päivikki Tanskanen
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  15. Juha Veijola
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Corresponding author

Correspondence to Matti Isohanni.

Additional information

Traduction de l’anglais: Caroline Demily (Rouen)

Ce travail a été rendu possible grâce aux subventions de la Finnish Academy, de la Sigrid Juselius Foundation et de la Theodore & Vada Stanley Foundation.

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Isohanni, M., Croudace, T., Isohanni, I. et al. Étude de la cohorte nord-finlandaise de 1966: facteurs prédictifs et conséquences de la schizophrénie. Psychiatr Sci Hum Neurosci 3 (Suppl 1), S8–S15 (2005). https://doi.org/10.1007/BF03020590

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