Abstract
Experiments were conducted to evaluate the effect of dietary benzo[a]pyrene (B[a]P) on the growth and hematological parameters of rockfish, Sebastes schlegeli, after they were fed with subchronic dietary B[a]P for 30 days. The weight growth rate of the rockfish was significantly different from that of the control group at dietary B[a]P concentration of 1.5 and 2.0 mg/kg. Significant reduction in red blood cells, hematocrit, and hemoglobin were observed during 30 days of exposure to the highest concentration. Over 30 days, serum AST increased at a B[a]P concentration of 1.5 mg/kg and LDH increased at a B[a]P concentration of 1.0 mg/kg concentration. However, no changes were observed in ALT, total protein, magnesium or calcium.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bálint T, Ferenczy J, Kátai F, Kiss I, Kráczer L, Kufcsák O, Láng G, Polyhos C, Szabó I, Szegletes T, Nemcsók J (1997) Similarities, differences between the massive eel (Anguilla anguilla L.) devastations that occurred in Lake Balaton in 1991 and 1995. Ecotoxicol Environ Saf 37:17–23. doi:10.1006/eesa.1996.1509
Boleas S, Fernandez C, Beyer J, Tarazona JV, Golsøyr A (1998) Accumulation and effects of benzo(a)pyrene on cytochrome P450 1A in waterborne exposed and intraperitoneal injected juvenile turbot (Scophthalmus maximus). Mar Environ Res 46:17–20. doi:10.1016/S0141-1136(98)00022-1
German Society for Clinical Chemistry (1972) Recommendations of the german association for clinical chemistry (DGKC). J Clinic Chem Clinic Biochem 10:182–193
Gill TS, Epple A (1993) Stress-related changes in the hematological profile of the American eel (Anguilla rostrata). Ecotoxicol Environ Saf 25:227–235. doi:10.1006/eesa.1993.1021
Haux C, Larsson A (1984) Long-term sublethal physiological effects in rainbow trout, Salmo gairdneri, during exposure to cadmium and after subsequent recovery. Aquatic Toxicol 5:129–142. doi:10.1016/0166-445X(84)90004-3
Heintz RA, Rice SD, Wertheimer AC, Bradshaw RF, Thrower FP, Joyce JE, Short JW (2000) Delayed effects on growth and marine survival of pink salmon Oncorhynchus gorbuscha after exposure to crude oil during embryonic development. Mar Ecol Prog Ser 208:205–216. doi:10.3354/meps208205
Holbrook DJ (1994) Effects of toxicants on nucleic acid and protein metabolism. In: Hodgson E, Levi PE (eds) Introduction to biochemical toxicology. Appleton & Langer, Conenecticut, pp 367–379
Jee JH, Kim SG, Kang JC (2004) Effects of phenanthrene on growth and basic physiological functions of the olive flounder, Paralichthys olivaceus. J Exp Mar Biol Ecol 304:123–136. doi:10.1016/j.jembe.2003.12.001
Kwon JY, Chang YJ (1996) Effects of ammonia concentration on histological and physiological status in black seabream Acanthopagrus schlegeli. J Korean Fish Soc 29:828–836
Lemaire P, Drai P, Mathieu A, Lemaire S, Carriere S, Giudicelli J, Lafaurie M (1991) Changes with different diets in plasma enzymes (GOT, GPT, LDH, ALP) and plasma lipids (cholesterol, triglycerides) of sea-bass (Dicentrachus labrax). Aquaculture 93:63–75. doi:10.1016/0044-8486(91)90205-L
Long SM, Ryder KJ, Holdwaya DA (2003) The use of respiratory enzymes as biomarkers of petroleum hydrocarbon exposure in Mytilus edulis planulatus. Ecotoxicol Environ Saf 55:261–270. doi:10.1016/S0147-6513(02)00137-9
Moles A, Babcock MM, Rice SD (1987) Effects of oil exposure on pink salmon, Oncorhynchus gorbuscha, alevins in a simulated intertidal environment. Mar Environ Res 21:49–58. doi:10.1016/0141-1136(87)90073-0
Nelson DL, Cox MM (2000) Lehninger Principles of Biochemistry, 3rd ed. Worth Publishers, New York
Reitman S, Frankel S (1957) A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clinic Pathol 28:56–63
Schwaiger J, Spieser OH, Bauer C, Ferling H, Mallow U, Kalbfus W, Negele RD (2000) Chronic toxicity of nonylphenol and ethinylestradiol: haematological and histopathological effects in juvenile common carp (Cyprinus carpio). Aquatic Toxicol 51:69–78. doi:10.1016/S0166-445X(00)00098-9
Vaglio A, Landriscina C (1999) Changes in liver enzyme activity in the teleost Sparus aurata in response to cadmium intoxication. Ecotoxicol Environ Saf 43:111–116. doi:10.1006/eesa.1999.1778
van der Oost R, Vindimianb E, van den Brink PJ, Satumalay K, Heida H, Vermeulend NPE (1997) Biomonitoring aquatic pollution with feral eel (Anguilla anguilla). III. Statistical analyses of relationships between contaminant exposure and biomarkers. Aquatic Toxicol 39:45–75. doi:10.1016/S0166-445X(96)00851-X
Walker GW, Livingstone DR (1992) Persistent pollutants in marine ecosystems. Pergamon Press, Oxford
Wedemeyer GA, Yasutake WT (1977) Clinical methods for the assessment of the effects of environmental stress on fish health. U.S. Tech Pap USFWS 89:1–18
Acknowledgement
This work is funded by a grant from the National Fisheries Research and Development Institute (RP-2008-ME-032) of Korea.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kim, S.G., Park, D.K., Jang, S.W. et al. Effects of Dietary Benzo[a]pyrene on Growth and Hematological Parameters in Juvenile Rockfish, Sebastes schlegeli (Hilgendorf). Bull Environ Contam Toxicol 81, 470–474 (2008). https://doi.org/10.1007/s00128-008-9499-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00128-008-9499-1