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Bioaccumulation and Distribution of Hexabromocyclododecane Isomers in Duck Tissues

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Abstract

Eighty ducks (Sheldrake, Anas platyrhynchos) from Zhejiang Province, China were fed capsules containing commercialized hexabromocyclododecanes (HBCDs) at low (0.8 mg/kg/day) or high (1.6 mg/kg/day) exposure level, or only maize starch for 21 days. Then the next 21 days was set as depuration period. Ducks were euthanizated at 0, 7, 14 and 21 days after last dose and ten duck tissues including skin, tongue, intestines, heart, gizzard, muscle, liver, lung, brain and blood were sampled, separately. Three HBCDs including α-HBCD, β-HBCD and γ-HBCD in duck tissue samples were analyzed. At the end of depuration period, the total HBCDs concentration in skin was significantly higher than those in the other tissues (p < 0.05). The elimination rates of the three isomers in skin, tongue, intestines, heart, gizzard and brain were in the order β- > γ- > α-HBCD. The enantioselectivity of three HBCDs enantiomers was also studied in ten duck tissues. It was shown that the EF (enrichment factor) for two γ-HBCD enantiomers was significant lower than 0.5 (p < 0.05) in gizzard, heart, muscle, tongue, intestinal and liver at the end of depuration day, showing a selective accumulation of (+)-γ-HBCD in these tissues. This study provided a reference for evaluation on the accumulation of the persistent contamination of HBCDs in edible poultry.

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Acknowledgements

This work was supported by support from the Zhejiang Provincial Natural Science Foundation of China (LY070002, LY14B070008), National Waterfowl Industry Technology System of China (CARS-42-27), the Project of Science and Technology Plan of Zhejiang Province (2014C32044), Nature Science Foundation of China (No. 21507114), State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control (2010DS700124-KF1701, 2010DS700124-ZZ1602, 2010DS700124-ZM1604).

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Authors and Affiliations

  1. College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310014, People’s Republic of China

    Wei Xia & Zuguang Li

  2. State Key Lab Breeding Base Zhejiang Sustainable, Institute of Quality and Standard for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, Zhejiang, People’s Republic of China

    Wei Xia, Jianmei Wang, Hua Yang, Hu Zhang, Yinhuan Zeng, Jie Xu & Mingrong Qian

  3. Hubei Engineering Research Center of Viral Vector, Wuhan Institute of Bioengineering, Wuhan, 430415, People’s Republic of China

    Bo Yang

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  1. Wei Xia
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  2. Jianmei Wang
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  3. Hua Yang
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  4. Hu Zhang
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  5. Bo Yang
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  6. Yinhuan Zeng
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  7. Jie Xu
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  8. Zuguang Li
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  9. Mingrong Qian
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Correspondence to Zuguang Li or Mingrong Qian.

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Xia, W., Wang, J., Yang, H. et al. Bioaccumulation and Distribution of Hexabromocyclododecane Isomers in Duck Tissues. Bull Environ Contam Toxicol 100, 754–759 (2018). https://doi.org/10.1007/s00128-018-2342-4

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  • DOI: https://doi.org/10.1007/s00128-018-2342-4

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