Abstract
In this study, the detection power of a gas chromatography mass spectrometer (GC–MS) for procymidone and chlorflurenol was significantly enhanced using switchable solvent liquid phase microextraction (SS-LPME) as a preconcentration tool. This was achieved by a comprehensive optimization of significant parameters to the SS-LPME method such as switchable solvent amount, concentration and amount of sodium hydroxide, pH effect and mixing effect. The optimum experimental conditions obtained were used to determine analytical figures of merit for the analytes. The limits of detection obtained were 0.44 and 2.9 ng/mL for procymidone and chlorflurenol, respectively. The optimum method was applied to water sampled from an irrigation canal and two wastewater samples. The samples were spiked at two concentrations and the percent recovery results obtained ranged between 86 and 115% for both analytes. The recovery results together with the low standard deviations recorded validated the method as accurate and precise.
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References
Alavanja MCR, Hoppin JA, Kamel F (2004) Health effects of chronic pesticide exposure: cancer and neurotoxicity. Annu Rev Public Health 25:155–197
Al-Rawi SM (2005) Contribution of man-made activities to the pollution of the tigris within mosul area/IRAQ. Int J Environ Res Public Health 2:245–250
Cao X, Limbach PA (2017) Mass Spectrometry: Nucleic Acids and Nucleotides Studied Using MS☆. In: Lindon JC, Tranter GE, Koppenaal DW (eds) Encyclopedia of spectroscopy and spectrometry, 3rd edn. Academic Press, Oxford, pp 764–771
Coskun O (2016) Separation techniques: chromatography. North Clin Istanb 3:156–160
Dalvie MA, Cairncross E, Solomon A, London L (2003) Contamination of rural surface and ground water by endosulfan in farming areas of the Western Cape, South Africa. Environ Health 2:1
Damalas CA, Koutroubas SD (2016) Farmers’ exposure to pesticides: toxicity types and ways of prevention. Toxics 4:1
Dooley EE (2005) EHPnet: UNEP.Net freshwater portal. Environ Health Perspect 113:A451–A451
Gondo TT, Obuseng VC, Mmualefe LC, Okatch H (2016) Employing solid phase microextraction as extraction tool for pesticide residues in traditional medicinal plants. J Anal Methods Chem 2016:2890219
Kponee KZ, Chiger A, Kakulu II, Vorhees D, Heiger-Bernays W (2015) Petroleum contaminated water and health symptoms: a cross-sectional pilot study in a rural Nigerian community. Environ Health 14:86
Liu Y, He M, Chen B, Hu B (2015) Solidification of floating organic drop microextraction combined with gas chromatography-flame photometric detection for the analysis of organophosphorus pesticides in water samples. Anal Methods 7:6182–6189
Memon ZM, Yilmaz E, Soylak M (2017) Switchable solvent based green liquid phase microextraction method for cobalt in tobacco and food samples prior to flame atomic absorption spectrometric determination. J Mol Liq 229:459–464
Oertel P, Bergmann A, Fischer S, Trefz P, Küntzel A, Reinhold P, Köhler H, Schubert JK, Miekisch W (2018) Evaluation of needle trap micro-extraction and solid-phase micro- extraction: obtaining comprehensive information on volatile emissions from in vitro cultures. Biomed Chromatogr 32:e4285
Özdoğan N, Kapukıran F, Mutluoğlu G, Chormey DS, Bakırdere S (2018) Simultaneous determination of iprodione, procymidone and chlorflurenol in lake water and wastewater matrices by GC-MS after multivariate optimization of binary dispersive liquid-liquid microextraction. Environ Monit Assess 190:607
Parrón T, Requena M, Hernández AF, Alarcón R (2014) Environmental exposure to pesticides and cancer risk in multiple human organ systems. Toxicol Lett 230:157–165
Pastor-Belda M, Garrido I, Campillo N, Viñas P, Hellín P, Flores P, Fenoll J (2015) Dispersive liquid–liquid microextraction for the determination of new generation pesticides in soils by liquid chromatography and tandem mass spectrometry. J Chromatogr A 1394:1–8
Qaqish BM, Al-Dalahmah O, Al-Motassem Y, Battah A, Ismail SS (2016) Occupational exposure to pesticides and occurrence of the chromosomal translocation t(14;18) among farmers in Jordan. Toxicol Rep 3:225–229
Raks V, Al-Suod H, Buszewski B (2018) Isolation, separation, and preconcentration of biologically active compounds from plant matrices by extraction techniques. Chromatographia 81:189–202
Reigart JR (2009) Recognition and management of pesticide poisonings. DIANE Publishing, Washington
Seebunrueng K, Santaladchaiyakit Y, Soisungnoen P, Srijaranai S (2011) Catanionic surfactant ambient cloud point extraction and high-performance liquid chromatography for simultaneous analysis of organophosphorus pesticide residues in water and fruit juice samples. Anal Bioanal Chem 401:1703
Sosa-Ferrera Z, Mahugo-Santana C, Santana-Rodríguez JJ (2013) Analytical methodologies for the determination of endocrine disrupting compounds in biological and environmental samples. Biomed Res Int 2013:674838
Soylak M, Khan M, Yilmaz E (2016) Switchable solvent based liquid phase microextraction of uranium in environmental samples: a green approach. Anal Methods 8:979–986
Tongo I, Ezemonye L (2015) Human health risks associated with residual pesticide levels in edible tissues of slaughtered cattle in Benin City, Southern Nigeria. Toxicol Rep 2:1117–1135
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Kapukıran, F., Fırat, M., Chormey, D.S. et al. Accurate and Sensitive Determination Method for Procymidone and Chlorflurenol in Municipal Wastewater, Medical Wastewater and Irrigation Canal Water by GC–MS After Vortex Assisted Switchable Solvent Liquid Phase Microextraction. Bull Environ Contam Toxicol 102, 848–853 (2019). https://doi.org/10.1007/s00128-019-02618-w
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DOI: https://doi.org/10.1007/s00128-019-02618-w