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Comparative Acute Toxicity and Oxidative Stress Responses in Three Aquatic Species Exposed to Stannic Oxide Nanoparticles and Stannic Chloride

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Abstract

We experimentally investigated the toxicity of stannic oxide nanoparticles (SnO2 NPs) to three freshwater species including Scenedesmus obliquus, Daphnia magna, and Danio rerio. To evaluate effect, toxicological impacts were compared to that of stannic chloride (SnCl4). Based on the actual concentration of Sn, SnO2 NPs suspensions inhibited growth of S. obliquus in a dose-dependent manner, demonstrating a median effect concentration of 2.28 ± 0.53 mg/L. However, SnO2 NP suspensions were found to exhibit limited acute toxicity in D. magna and D. rerio. Moreover, the toxicity of the SnO2 NP suspension was lower than SnCl4 for all three trophic aquatic organisms. Comparison of component-specific contribution to overall toxicity indicated that, in SnO2 NP suspensions, particulate Sn more significantly contributed to toxicity than dissolved Sn-ions. Furthermore, we found that the toxic mechanism of the SnO2 NP suspension involved the induction of oxidative stress by increasing intracellular ROS accumulation.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (Grant Number 31971522), the Natural Science Foundation of Jiangsu Province (Grant Number BK20191403), and Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control (Grant Number 2017B030301012). We are grateful for the technical help from Yinghan Liu (Nanjing University of Information Science and Technology) with the fluorescent measurements. We thank the editor and the reviewers for constructive comments and suggestions.

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Authors and Affiliations

  1. School of Environmental Science and Engineering, Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control, Nanjing University of Information Science and Technology, Nanjing, 210044, People’s Republic of China

    Zhuang Wang & Fan Zhang

  2. State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control, School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen, 518055, People’s Republic of China

    Lan Song

  3. Shenzhen Institute of Sustainable Development, Shenzhen, 518055, People’s Republic of China

    Lan Song

  4. College of Environmental Science and Engineering, Dalian Maritime University, Dalian, 116026, People’s Republic of China

    De-Gao Wang

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  1. Zhuang Wang
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  2. Lan Song
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  3. Fan Zhang
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Correspondence to Zhuang Wang.

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Wang, Z., Song, L., Zhang, F. et al. Comparative Acute Toxicity and Oxidative Stress Responses in Three Aquatic Species Exposed to Stannic Oxide Nanoparticles and Stannic Chloride. Bull Environ Contam Toxicol 105, 841–846 (2020). https://doi.org/10.1007/s00128-020-03052-z

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  • DOI: https://doi.org/10.1007/s00128-020-03052-z

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