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Effect of postural alignment alteration with age on vertebral strength

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Abstract

Summary

EOS biplane radiographs of 117 subjects between 20 and 83 years were analyzed to compute the upper body lever arm over the L1 vertebra and its impact on vertebral strength. Postural sagittal alignment alteration was observed with age and resulted in a greater lever arm causing vertebral strength to decrease.

Purpose

The purpose of this study was to analyze the impact of postural alignment changes with age on vertebral strength using finite element analysis and barycentremetry.

Methods

A total of 117 subjects from 20 to 83 years were divided in three age groups: young (20 to 40 years, 62 subjects), intermediate (40 to 60 years, 26 subjects), and elderly (60 years and over, 29 subjects). EOS biplane radiographs were acquired, allowing 3D reconstruction of the spine and body envelope as well as spinal, pelvic, and sagittal alignment parameter measurements. A barycentremetry method allowed the estimation of the mass and center of mass (CoM) position of the upper body above L1, relatively to the center of the L1 vertebra (lever arm). To investigate the effect of this lever arm, vertebral strength of a generic finite element model (with constant geometry and mechanical properties for all subjects) was successively computed applying the personalized lever arm of each subject.

Results

A combination of an increase in thoracic kyphosis, cervical lordosis, and pelvic tilt with a loss of lumbar lordosis was observed between the young and the older groups. Sagittal alignment parameters indicated a more forward position as age increased. The lever arm of the CoM above L1 varied from an average of 1 mm backward for the young group, to averages of 10 and 24 mm forward, respectively, for the intermediate and elderly group. As a result, vertebral strength decreased from 2527 N for the young group to 1820 N for the elderly group.

Conclusion

The global sagittal alignment modifications observed with age were consistent with the literature. Posture alteration with age reduced vertebral strength significantly in this simplified loading model. Postural alignment seems essential to be considered in the evaluation of osteoporotic patients.

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Acknowledgements

The authors thank the ParisTech BiomecAM chair program on subject-specific musculoskeletal modelling and in particular Société Générale and COVEA.

Funding

This work was supported by the ParisTech BiomecAM chair program.

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Authors and Affiliations

  1. Arts Et Métiers ParisTech, Institut de Biomécanique Humaine Georges Charpak, Paris, France

    C. Heidsieck, L. Gajny & W. Skalli

  2. Department of Orthopaedic and Trauma Surgery, Pitié-Salpétrière Hospital, Assistance Publique-Hopitaux de Paris, Sorbonne University, Paris, France

    C. Travert & J.-Y. Lazennec

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  1. C. Heidsieck
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Correspondence to C. Heidsieck.

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Heidsieck, C., Gajny, L., Travert, C. et al. Effect of postural alignment alteration with age on vertebral strength. Osteoporos Int 33, 443–451 (2022). https://doi.org/10.1007/s00198-021-06093-0

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