Skip to main content

Advertisement

SpringerLink
Log in

Disproportionality analysis for identification of drug safety signals in a database shared by the Norwegian network of drug information centres (RELIS)

  • Letter to the Editor
  • Published:
European Journal of Clinical Pharmacology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Schjøtt J, Reppe LA, Roland PD,Westergren T (2012) A question-answer pair (QAP) database integrated with websites to answer complex questions submitted to the Regional Medicines Information and Pharmacovigilance Centres in Norway (RELIS): a descriptive study. BMJ Open 2:e000642

  2. Schjøtt J. (2017) Benefits of a national network of drug information centres: RELIS. Eur J Clin Pharmacol. 73(1):125–126.

  3. Harpaz R, DuMouchel W, Shan NH, Mdigan D, Ryan P, Friedman C (2012) Novel data-mining methodologies for adverse drug event discovery and analysis. Clin Pharmacol Ther 91(6):1010–1021

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Ventola CL (2018) Big data and pharmacovigilance: data mining for adverse drug events and interactions. P T 43(6):340–351

    PubMed  PubMed Central  Google Scholar 

  5. Anon (2016) Quetiapine: misuse and abuse. Prescrire Int 25(169):68

    Google Scholar 

  6. Chiappini S, Schifano F (2018) Is there a potential of misuse for quetiapine?: literature review and analysis of the European Medicines Agency/European Medicines Agency adverse drug reactions’ database. J Clin Psychopharmacol 38(1):72–79

    PubMed  Google Scholar 

  7. Lee J, Pilgrim J, Gerostamoulos D, Robinson J, Wong A (2018) Increasing rates of quetiapine overdose, misuse, and mortality in Victoria, Australia. Drug Alcohol Depend 187:95–99

    Article  CAS  PubMed  Google Scholar 

  8. Evoy KE, Morrison MD, Saklad SR (2017) Abuse and misuse of pregabalin and gabapentin. Drugs 77(4):403–426

    Article  CAS  PubMed  Google Scholar 

  9. Schifano F (2014) Misuse and abuse of pregabalin and gabapentin: cause for concern? CNS Drugs 28(6):491–496

    Article  CAS  PubMed  Google Scholar 

  10. Bonnet U, Scherbaum N (2017) How addictive are gabapentin and pregabalin? A systematic review. Eur Neuropsychopharmacol 27(12):1185–1215

    Article  CAS  PubMed  Google Scholar 

  11. Driot D, Jouanjus E, Oustric S, Dupouy J, Lapeyre-Mestre M (2019) Patterns of gabapentin and pregabalin use and misuse: Results of a population-based cohort study in France. Br J Clin Pharmacol. https://doi.org/10.1111/bcp.13892

  12. Böhm R. Primer on disproportionality analysis. Version: 2018-10-16. http://openvigil.sourceforge.net/doc/DPA.pdf. Accessed 10th April 2019

Download references

Author information

Authors and Affiliations

  1. Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5021, Bergen, Norway

    Charlotte L. Stokes & Jan Schjøtt

  2. Department of Clinical Science, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway

    Jan Schjøtt

Authors
  1. Charlotte L. Stokes
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jan Schjøtt
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

The manuscript was drafted by the idea of Jan Schjøtt, who is also responsible for the statistics. Charlotte L. Stokes has contributed in writing, reference search, and submission.

Corresponding author

Correspondence to Charlotte L. Stokes.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Stokes, C.L., Schjøtt, J. Disproportionality analysis for identification of drug safety signals in a database shared by the Norwegian network of drug information centres (RELIS). Eur J Clin Pharmacol 75, 1469–1470 (2019). https://doi.org/10.1007/s00228-019-02717-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00228-019-02717-x

Keywords

Search

Navigation