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A Single-Institution Experience in Percutaneous Image-Guided Biopsy of Malignant Pleural Mesothelioma

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Abstract

Purpose

Mesothelioma has been considered a difficult pathologic diagnosis to achieve via image-guided core needle biopsy. The purpose of this study was to assess the diagnostic sensitivity of percutaneous image-guided biopsy for diagnosis of pleural mesothelioma.

Materials and Methods

Retrospective review was performed to identify patients with a confirmed diagnosis of pleural mesothelioma and who underwent image-guided needle biopsy between January 1, 2002, and January 1, 2016. Thirty-two patients with pleural mesothelioma were identified and included for analysis in 33 image-guided biopsy procedures. Patient, procedural, and pathologic characteristics were recorded. Complications were characterized via standardized nomenclature [Common Terminology for Clinically Adverse Events (CTCAE)].

Results

Percutaneous image-guided biopsy was associated with an overall sensitivity of 81%. No CTCAE clinically significant complications were observed. No image-guided procedures were complicated by pneumothorax or necessitated chest tube placement. No patients had tumor seeding of the biopsy tract.

Conclusion

Percutaneous image-guided biopsy can achieve high sensitivity for pathologic diagnosis of pleural mesothelioma with a low procedural complication rate, potentially obviating need for surgical biopsy.

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Authors and Affiliations

  1. Department of Radiology, Mayo Clinic, 200 1st ST SW, Rochester, MN, 55905, USA

    B. T. Welch, P. W. Eiken, T. D. Atwell & G. D. Schmit

  2. Department of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 1st ST SW, Rochester, MN, 55905, USA

    T. Peikert

  3. Department of Pathology, Mayo Clinic, 200 1st ST SW, Rochester, MN, 55905, USA

    E. S. Yi

  4. Department of Thoracic Surgery, Mayo Clinic, 200 1st ST SW, Rochester, MN, 55905, USA

    F. Nichols

Authors
  1. B. T. Welch
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  2. P. W. Eiken
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  3. T. D. Atwell
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  4. T. Peikert
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  5. E. S. Yi
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  6. F. Nichols
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  7. G. D. Schmit
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Correspondence to B. T. Welch.

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All authors have no conflicts of interest to disclose.

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Welch, B.T., Eiken, P.W., Atwell, T.D. et al. A Single-Institution Experience in Percutaneous Image-Guided Biopsy of Malignant Pleural Mesothelioma. Cardiovasc Intervent Radiol 40, 860–863 (2017). https://doi.org/10.1007/s00270-017-1583-7

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  • DOI: https://doi.org/10.1007/s00270-017-1583-7

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