Abstract
Pectus excavatum (PE) is a relatively common deformity involving the anterior chest wall. It is represented clinically as a conical depression of the sternum and costal cartilages with the apex at the xiphoid process. Associated features and symptoms vary but generally involve respiratory and cardiac abnormalities. Since it’s initial description, numerous surgical techniques have been developed to correct PE, with the Ravtich (open) and Nuss (minimally invasive) procedures being the most commonly employed. Although the etiology remains unclear, the pathogenesis of PE is currently thought to involve the overgrowth of the costochondral region of the ribs. In addition, documented case reports of familial pectus excavatum exist, suggesting a heritable form of the defect. Numerous genetic markers have also been discovered, linking PE to various genetic syndromes.
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Antonoff MB, Erickson AE, Hess DJ, Acton RD, Saltzman DA (2009) When patients choose: comparison of Nuss, Ravitch, and Leonard procedures for primary repair of pectus excavatum. J Pediatr Surg 44:1113–1118
Aronson DC, Bosgraaf RP, van der Horst C, Ekkelkamp S (2007) Nuss procedure: pediatric surgical solution for adults with pectus excavatum. World J Surg 31:26–29
Boehm RA, Muensterer OJ, Till H (2004) Comparing minimally invasive funnel chest repair versus the conventional technique: an outcome analysis in children. Plast Reconstr Surg 114:668–673
Brown AL, Cook O (1951) Funnel chest (pectus excavatum) in infancy and adult life. Calif Med 74:174–178
Cartoski MJ, Nuss D, Goretsky MJ, Proud VK, Croitoru DP, Gustin T, Mitchell K, Vasser E, Kelly RE Jr (2006) Classification of the dysmorphology of pectus excavatum. J Pediatr Surg 41:1573–1581
Castellani C, Windhaber J, Schober PH, Hoellwarth ME (2010) Exercise performance testing in patients with pectus excavatum before and after Nuss procedure. Pediatr Surg Int 26:659–663
Chen CH, Liu HC, Hung TT, Chen CH (2010) Ann Thorac Surg 89:599–601
Chin EF (1957) Surgery of funnel chest and congenital sternal prominence. Br J Surg 44:360–376
Coln D, Gunning T, Ramsay M, Swygert T, Vera R (2002) Early experience with the Nuss minimally invasive correction of pectus excavatum in adults. World J Surg 26:1217–1221
Colombani PM (2009) Preoperative assessment of chest wall deformities. Semin Thorac Cardiovasc Surg 21:58–63
Creswick HA, Stacey MW, Kelly RE Jr, Gustin T, Nuss D, Harvey H, Goretsky MJ, Vasser E, Welch JC, Mitchell K, Proud VK (2006) Family study of the inheritance of pectus excavatum. J Pediatr Surg 41:1699–1703
Croitoru DP, Kelly RE Jr, Goretsky MJ, Lawson ML, Swoveland B, Nuss D (2002) Experience and modification update for the minimally invasive Nuss technique for pectus excavatum repair in 303 patients. J Pediatr Surg 37:437–445
Davis JT, Weinstein S (2004) Repair of the pectus deformity: results of the Ravitch approach in the current era. Ann Thorac Surg 78:421–426
Fonkalsrud EW (2003) Current management of pectus excavatum. World J Surg 27:502–508
Fonkalsrud EW, Beanes S, Hebra A, Adamson W, Tagge E (2002) Comparison of minimally invasive and modified Ravitch pectus excavatum repair. J Pediatr Surg 37:413–417
Fonkalsrud EW, DeUgarte D, Choi E (2002) Repair of pectus excavatum and carinatum deformities in 116 adults. Ann Surg 236:304–312
Fonkalsrud EW, Dunn JC, Atkinson JB (2000) Repair of pectus excavatum deformities: 30 years of experience with 375 patients. Ann Surg 231:443–448
Goretsky MJ, Kelly RE Jr, Croitoru D, Nuss D (2004) Chest wall anomalies: pectus excavatum and pectus carinatum. Adolesc Med Clin 15:455–471
Guntheroth WG, Spiers PS (2007) Cardiac function before and after surgery for pectus excavatum. Am J Cardiol 99:1762–1764
Haecker FM (2011) The vacuum bell for conservative treatment of pectus excavatum: the Basle experience. Pediatr Surg Int (Epub ahead of print)
Haller JA Jr, Scherer LR, Turner CS, Colombani PM (1989) Evolving management of pectus excavatum based on a single institutional experience of 664 patients. Ann Surg 209:578–582
Hiroshi I (2010) Surgical repair of pectus excavatum. Gen Thorac Cardiovasc Surg 58:55–61
Humphreys GH II, Jaretzki A (1980) Pectus excavatum. Late results with and without operation. J Thorac Cardiovasc Surg 80:686
Jaroszewski D, Notrica D, McMahon L, Steidley DE, Deschamps CJ (2010) Current management of pectus excavatum: a review and update of therapy and treatment recommendations. Am Board Fam Med 23:230–239
Kelly RE Jr (2008) Pectus excavatum: historical background, clinical picture, preoperative evaluation and criteria for operation. Semin Pediatr Surg 17:181–193
Kelly RE Jr, Cash TF, Shamberger RC, Mitchell KK, Mellins RB, Lawson ML, Oldham K, Azizkhan RG, Hebra AV, Nuss D, Goretsky MJ, Sharp RJ, Holcomb GW 3rd, Shim WK, Megison SM, Moss RL, Fecteau AH, Colombani PM, Bagley T, Quinn A, Moskowitz AB (2008) Surgical repair of pectus excavatum markedly improves body image and perceived ability for physical activity: multicenter study. Pediatrics 122:1218–1222
Kelly RE Jr, Shamberger RC, Mellins RB, Mitchell KK, Lawson ML, Oldham K, Azizkhan RG, Hebra AV, Nuss D, Goretsky MJ, Sharp RJ, Holcomb GW 3rd, Shim WK, Megison SM, Moss RL, Fecteau AH, Colombani PM, Bagley TC, Moskowitz AB (2007) Prospective multicenter study of surgical correction of pectus excavatum: design, perioperative complications, pain, and baseline pulmonary function facilitated by internet-based data collection. J Am Coll Surg 205:205–216
Kotzot D, Schwabegger AH (2009) Etiology of chest wall deformities—a genetic review for the treating physician. J Pediatr Surg 44:2004–2011
Koumbourlis AC, Stolar CJ (2004) Lung growth and function in children and adolescents with idiopathic pectus excavatum. Pediatr Pulmonol 38:339–343
Krueger T, Chassot PG, Christodoulou M, Cheng C, Ris HB, Magnusson L (2010) Cardiac function assessed by transesophageal echocardiography during pectus excavatum repair. Ann Thorac Surg 89:240–243
Lam MW, Klassen AF, Montgomery CJ, LeBlanc JG, Skarsgard ED (2008) Quality-of-life outcomes after surgical correction of pectus excavatum: a comparison of the Ravitch and Nuss procedures. J Pediatr Surg 43:819–825
Lacquet LK, Morshuis WJ, Folgering HT (1998) Long-term results after correction of anterior chest wall deformities. J Cardiovasc Surg (Torino) 39:683
Lester CW (1946) The surgical treatment of funnel chest. Ann Surg 123:1003–1022
Loeys BL, Dietz HC (2008) Loeys-Dietz syndrome. Gene Rev. http://www.ncbi.nlm.nih.gov/books/NBK1133/#loeys-dietz-20301312. Accessed Feb 2011
Malek MH, Berger DE, Housh TJ, Coburn JW, Marelich WD, Beck TW (2006) Cardiovascular function following surgical repair of pectus excavatum: a metaanalysis. Chest 130:16–506
Malek MH, Fonkalsrud EW, Cooper CB (2003) Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum. Chest 124:870–882
Mansour KA, Thourani VH, Odessey EA, Durham MM, Miller JI Jr, Miller DL (2003) Thirty-year experience with repair of pectus deformities in adults. Ann Thorac Surg 76:5–391
Meyer L (1911) ZurchirurgischenBehandlung der angerborenenTtrichterburst. Verh Berliner Med 42:364–373
Morshuis W, Folgering H, Barentsz J, van Lier H, Lacquet L (1994) Pulmonary function before surgery for pectus excavatum and at long-term follow-up. Chest 105:1646–1652
Nagasao T, Noguchi M, Miyamoto J, Jiang H, Ding W, Shimizu Y, Kishi K (2010) Dynamic effects of the Nuss procedure on the spine in asymmetric pectus excavatum. J Thorac Cardiovasc Surg 140:1294–1299
Nasr A, Fecteau A, Wales PW (2010) Comparison of the Nuss and the Ravitch procedure for pectus excavatum repair: a meta-analysis. J Pediatr Surg 45:880–886
Nuss D, Kelly RE Jr, Croitoru DP, Katz ME (1998) A 10 years review of a minimally invasive technique for correction of pectus excavatum. J Pediatr Surg 33:545–552
Ochsner A, DeBakey M (1939) Chonechondrosternon. J Thorax Surg 8:469
Ohno K, Nakamura T, Azuma T, Yamada H, Hayashi H, Masahata K (2009) Modification of the Nuss procedure for pectus excavatum to prevent cardiac perforation. J Pediatr Surg 44:30–2426
Ravitch MM (1949) The operative treatment of pectus excavatum. Ann Surg 129:429–444
Rehbein F, Wernicke HH (1957) The operative treatment of the funnel chest. Arch Dis Child 32:5–8
Rowland T, Moriarty K, Banever G (2005) Effect of pectus excavatum deformity on cardiorespiratory fitness in adolescent boys. Arch Pediatr Adolesc Med 159:1069–1073
Sauerbruch EF (1927) Die Chirurgie der Brustorgane. Springer, Berlin, pp 734–741
Schoenwolf GC, Bleyl SB, Brauer PR, Francis-West PH (2009) Larsen’s human embryology, 4th edn. Churchill Livingstone, Philidelphia, pp 227–228
Shamberger R (1996) Congenital chest wall deformities. CurrProbl Surg 33:469–552
Shamberger RC (2000) Cardiopulmonary effects of anterior chest wall deformities. Chest Surg Clin N Am 10:245–252
Snyder LH, Curtis GM (1934) An inherited “hollow chest”. J Heredity 25:445–447
Standring S (2008) Chest wall and breast. In: Gray’s anatomy, 40th edn. Churchill Livingstone, New York, pp 915–938
Stoddard ES (1939) The inheritance of “hollow chest”: “Cobbler’s chest” due to heredity—not an occupational deformity. J Hered 30:139–141
Waters P, WelchK Micheli LJ, Shamberger R, Hall JE (1989) Scoliosis in children with pectus excavatum and pectus carinatum. J Pediatr Orthop 9:551–556
Wu FZ, Huang YL (2010) Images in clinical medicine. Funnel chest. N Engl J Med 363:1559
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Dean, C., Etienne, D., Hindson, D. et al. Pectus excavatum (funnel chest): a historical and current prospective. Surg Radiol Anat 34, 573–579 (2012). https://doi.org/10.1007/s00276-012-0938-7
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DOI: https://doi.org/10.1007/s00276-012-0938-7