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The effects of spirulina on allergic rhinitis

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

The prevalence of allergic rhinitis is increasing globally due to various causes. It affects the quality life of a large group of people in all around the world. Allergic rhinitis still remains inadequately controlled with present medical means. The need of continuous medical therapy makes individuals anxious about the side effects of the drugs. So there is a need for an alternative strategy. Effects of spirulina, tinospora cordifolia and butterbur were investigated recently on allergic rhinitis in just very few investigations. Spirulina represents a blue-green alga that is produced and commercialized as a dietary supplement for modulating immune functions, as well as ameliorating a variety of diseases. This double blind, placebo controlled study, evaluated the effectiveness and tolerability of spirulina for treating patients with allergic rhinitis. Spirulina consumption significantly improved the symptoms and physical findings compared with placebo (P < 0.001***) including nasal discharge, sneezing, nasal congestion and itching. Spirulina is clinically effective on allergic rhinitis when compared with placebo. Further studies should be performed in order to clarify the mechanism of this effect.

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References

  1. Mao TK, Van de Water J, Gershwi ME (2005) Effects of a spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. J Med Food 8(1):27–30

    Article  PubMed  CAS  Google Scholar 

  2. Badar VA, Thawani VR, Wakode PT, Shrivastava MP, Gharpure KJ, Hingorani LL, Khiyani RM (2005) Efficacy of Tinospora cordifolia in allergic rhinitis. J Ethnopharmacol 96(3):445–449

    Article  PubMed  CAS  Google Scholar 

  3. Karkos PD, Leong SC, Arya AK, Papouliakos SM, Apostolidou MT (2006) Issing WJ’Complementary ENT’: a systematic review of commonly used supplements. J Laryngol Otol 24:1–4

    Google Scholar 

  4. Chen LL, Zhang SF, Huang DN, Tan JQ, He SH (2005) Experimental study of spirulina platensis in treating allergic rhinitis in rats. Zhong Nan Da Xue Xue Bao Yi Xue Ban 30(1):96–98

    PubMed  Google Scholar 

  5. Fox Ripley (2001) Mix-dry the Spirulina. J Fish Aquat Sci, ISSN 1300–1590, vol 18/1 Supplement. 1st algal technology symposium. European J Phycology

  6. Karasulu Y, Conk-Dalay M, Şanal E, Güneri T (2001) Quality control Studies of Tablets and Capsules prepared with Spirulina platensis (Cyanophyta). J Fish Aquatc Sci, ISSN 1300–1590, vol 18/1 Supplement.1st algal technology symposium. European J Phycology

  7. Gonzalez R, Rodriguez S, Romay C et al. (1999) Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats. Pharmacol Res 39:55–59

    Article  PubMed  CAS  Google Scholar 

  8. Yang HN, Lee EH, Kim HM (1997) Spirulina platensis inhibits anaphylactic reaction. Life Sci 61:1237–1244

    Article  PubMed  CAS  Google Scholar 

  9. Kim HM, Lee EH, Cho HH, Moon YH (1998) Inhibitory effect of mast cell-mediated immediate-type allergic reactions in rats by Spirulina. Biochem Pharmacol 55:1071–1076

    Article  PubMed  CAS  Google Scholar 

  10. Price JA III, Sanny C, Shevlin D (2002) Inhibition of mast cells by algae. J Med Food 5:205–210

    Article  PubMed  CAS  Google Scholar 

  11. Kurt E, Bavbek S, Pasaoglu G, Abadoglu O, Misirligil Z (2004) Use of alternative medicines by allergic patients in Turkey. Allergol Immunopathol (Madr) 32(5):289–294

    Article  CAS  Google Scholar 

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Correspondence to Cemal Cingi.

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Cingi, C., Conk-Dalay, M., Cakli, H. et al. The effects of spirulina on allergic rhinitis. Eur Arch Otorhinolaryngol 265, 1219–1223 (2008). https://doi.org/10.1007/s00405-008-0642-8

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  • DOI: https://doi.org/10.1007/s00405-008-0642-8

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