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Prevalence of Dysphagia in Patients with Gastroesophageal Reflux in Germany

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Abstract

Dysphagia is an alarming symptom that raises the possibility of stricture or malignancy. This study compares the prevalence and severity of dysphagia symptoms in subjects with or without gastroesophageal reflux (GERD). In a population-based study, 500 residents of Cologne between the ages of 20 and 90 years [232 (46%) males and 268 (54%) females] were randomly selected from the city register and sent questionnaires with reflux-related questions. Two hundred sixty-eight replies (54%) were accepted into the study. Of these, 45% were men with a median age of 58 years. The median female age was 54 years. Thirty-four percent of the respondents (n = 92) admitted having heartburn symptoms. There was no significant gender-based difference. There was little variation in reflux frequency between individual age groups. Twenty-three (25%) of the 92 respondents with reflux reported symptoms more than twice per week. Forty-five percent of this “reflux” group took medications for their heartburn. Swallowing difficulties, predominantly mild, were reported in 11.3% of the respondents. Dysphagia was significantly increased in the reflux group (28%) versus the normal group (3%) (p < 0.001). Sixteen percent of respondents with mild and 65% of those with moderate to severe reflux symptoms reported additional dysphagia symptoms (p < 0.001). Swallowing problems are common in patients with GERD. Approximately two thirds of patients with long-term and severe reflux symptoms also have dysphagia symptoms. Dysphagia should always be investigated by a physician.

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References

  1. Vakil N, Traxler B, Levine D. Dysphagia in patients with erosive esophagitis: prevalence, severity, and response to proton pump inhibitor treatment. Clin Gastroenterol Hepatol 2004;2:665–668.

    Article  PubMed  CAS  Google Scholar 

  2. Leers J, Bollschweiler E, Holscher A. Symptoms in patients with adenocarcinoma of the esophagus. Z Gastroenterol 2005;43:275–280.

    Article  PubMed  CAS  Google Scholar 

  3. Dent J. Gastro-oesophageal reflux disease. Digestion 1998;59:433–445.

    Article  PubMed  CAS  Google Scholar 

  4. Bardhan KD, Royston C, Nayyar AK. Reflux rising! A disease in evolution? Gastroenterology 2000;118:A478–A478.

    Article  Google Scholar 

  5. Bardhan KD, Royston C, Nayyar AK. Reflux rising! An essay on witnessing a disease in evolution. Dig Liver Dis 2006;38:163–168.

    Article  PubMed  CAS  Google Scholar 

  6. Ronkainen J, Aro P, Storskrubb T, Johansson S, Lind T, Bolling-Sternevald E, Graffner H, Vieth M, Stolte M, Engstrand L, Talley N, Agreus L. High prevalence of gastroesophageal reflux symptoms and esophagitis with or without symptoms in the general adult Swedish population: a Kalixanda study report. Scand J Gastroenterol 2005;40:275–285.

    Article  PubMed  Google Scholar 

  7. Chiocca J, Olmos J, Salis G, Soifer L, Higa R, Marcolongo M. Prevalence, clinical spectrum and atypical symptoms of gastro-oesophageal reflux in Argentina: a nationwide population-based study. Aliment Pharmacol Ther 2005;22:331–342.

    Article  PubMed  CAS  Google Scholar 

  8. Nocon M, Labenz J, Willich SN. Lifestyle factors and symptoms of gastro-oesophageal reflux - a population-based study. Aliment Pharmacol Ther 2006;23:169–174.

    Article  PubMed  CAS  Google Scholar 

  9. Dent J, El-Serag H, Wallander M, Johansson S. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2005;54:710–717.

    Article  PubMed  CAS  Google Scholar 

  10. El-Serag H, Petersen N, Carter J, Graham D, Richardson P, Genta R, Rabeneck L. Gastroesophageal reflux among different racial groups in the United States. Gastroenterology 2004;126:1692–1699.

    Article  PubMed  Google Scholar 

  11. Ponce J, Vegazo O, Beltran B, Jimenez J, Zapardiel J, Calle D, Piques JM. Prevalence of gastro-oesophageal reflux disease in Spain and associated factors. Aliment Pharmacol Ther 2006;23:175–183.

    Article  PubMed  CAS  Google Scholar 

  12. Wong BCY, Kinoshita Y. Systematic review on epidemiology of gastroesophageal reflux disease in Asia. Clin Gastroenterol Hepatol 2006;4:398–407.

    Article  PubMed  Google Scholar 

  13. Cho YS, Choi MG, Jeong JJ, Chung WC, Lee IS, Kim SW, Han SW, Choi KY, Chung IS. Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Asan-si, Korea. Am J Gastroenterol 2005;100:747–753.

    Article  PubMed  Google Scholar 

  14. Kawashima K, Motohashi Y, Fujishima I. Prevalence of dysphagia among community-dwelling elderly individuals as estimated using a questionnaire for dysphagia screening. Dysphagia 2004;19:266–271.

    PubMed  Google Scholar 

  15. Hollenz M, Stolte M, Labenz J. [Prevalence of gastro-oesophageal reflux disease in general practice]. Dtsch Med Wochenschr 2002;127:1007–1012.

    Article  PubMed  CAS  Google Scholar 

  16. Paciaroni M, Mazzotta G, Corea F, Caso V, Venti M, Milia P, Silvestrelli G, Palmerini F, Parnetti L, Gallai V. Dysphagia following stroke. Eur Neurol 2004;51:162–167.

    Article  PubMed  Google Scholar 

  17. Lagergren J, Bergström R, Lindgren A, Nyren O. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med 1999;18:825–831.

    Article  Google Scholar 

  18. Bollschweiler E, Wolfgarten E, Gutschow C, Holscher AH. Demographic variations in the rising incidence of esophageal adenocarcinoma in white males. Cancer 2001;92:549–555.

    Article  PubMed  CAS  Google Scholar 

  19. Pera M. Trends in incidence and prevalence of specialized intestinal metaplasia, Barrett’s esophagus, and adenocarcinoma of the gastroesophageal junction. World J Surg 2003;27:999–1008; discussion 1006–1008.

    Article  PubMed  Google Scholar 

  20. Carlsson R, Dent J, Bolling-Sternevald E, Johnsson F, Junghard O, Lauritsen K, Riley S, Lundell L. The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease. Scand J Gastroenterol 1998;33:1023–1029.

    Article  PubMed  CAS  Google Scholar 

  21. Isolauri J, Laippala P. Prevalence of symptoms suggestive of gastroesophageal reflux disease in an adult population. Ann Med 1995;27:67–70.

    Article  PubMed  CAS  Google Scholar 

  22. Terry P, Lagergren J, Wolk A, Nyren O. Reflux-inducing dietary factors and risk of adenocarcinoma of the esophagus and gastric cardia. Nutr Cancer 2000;38:186–191.

    Article  PubMed  CAS  Google Scholar 

  23. Nilsson M, Johnsen R, Ye W, Hveem K, Lagergren J. Prevalence of gastro-oesophageal reflux symptoms and the influence of age and sex. Scand J Gastroenterol 2004;39:1040–1045.

    Article  PubMed  CAS  Google Scholar 

  24. Valle C, Broglia F, Pistorio A, Tinelli C, Perego M. Prevalence and impact of symptoms suggestive of gastroesophageal reflux disease. Dig Dis Sci 1999;44:1848–1852.

    Article  PubMed  CAS  Google Scholar 

  25. Bretagne JF, Richard-Molard B, Honnorat C, Caekaert A, Barthelemy P. Gastroesophageal reflux in the French general population: national survey of 8000 adults. Presse Med 2006;35:23–31.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany

    Elfriede Bollschweiler, Katharina Knoppe, Eva Wolfgarten & Arnulf H. Hölscher

  2. Klinik und Poliklinik für Visceral- und Gefäßchirurgie, der Universität zu Köln, Joseph Stelzmann Strasse 9, 50931, Köln, Germany

    Elfriede Bollschweiler

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  1. Elfriede Bollschweiler
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  2. Katharina Knoppe
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  3. Eva Wolfgarten
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  4. Arnulf H. Hölscher
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Correspondence to Elfriede Bollschweiler.

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Bollschweiler, E., Knoppe, K., Wolfgarten, E. et al. Prevalence of Dysphagia in Patients with Gastroesophageal Reflux in Germany. Dysphagia 23, 172–176 (2008). https://doi.org/10.1007/s00455-007-9120-5

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  • DOI: https://doi.org/10.1007/s00455-007-9120-5

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