Skip to main content

Advertisement

SpringerLink
Log in

Gallbladder cancer: laparoscopic and classic cholecystectomy

  • Original article
  • Published:
Surgical Endoscopy And Other Interventional Techniques Aims and scope Submit manuscript

Abstract

Background: Gallbladder carcinoma is an abdominal malignancy with an extraordinarily poor prognosis that depends on the stage at the time of the diagnosis. Methods: In the past 8 years, 3,158 laparoscopic cholecystectomies (LC), and 8 years before that, 3,083 classic cholecystectomies (CC) were performed in the authors’ department. Results: In 15 LC cases and 7 CC cases, gallbladder carcinoma was found. There was preoperative or intraoperative suspicion of malignancy in 3 LC and 5 CC cases. According to the tumor–node–metastasis (TNM) classification system, these cases were categorized as stage 3 (S3) or S4, and resumption of the operation was necessary. Two LC cases and five CC cases were inoperable malignancies requiring palliative treatment. The others were managed with surgery for the completion of an extended cholecystectomy. The survival rate for all the patients was less than 1 month. In 12 LC cases and 2 CC cases, malignancy was diagnosed postoperatively. The stages for the LC group were S1(T in situ) in four cases and S1(T1) in eight cases. The stage for the CC group was S1(T1) in both cases. After simple LC or CC, the survival time was more than 2 years for eight patients and more than 3 years for four patients. Two patients were still alive, respectively, 1 and 2 years postoperatively. The difference in the numbers of diagnosed and resected gallbladder carcinoma in the earlier stages between the LC and CC groups is statistically significant (p < 0.0l). Conclusions: With the increased use of LC for presumed gallstone disease, the diagnosis and removal of gallbladder carcinoma in the earlier stages could be more frequent.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2
Figure 3

Similar content being viewed by others

References

  1. S Contini R Dalla Valle R Zinicola (1999) ArticleTitleUnexpected gallbladder cancer after laparoscopic cholecystectomy: an emerging problem? Reflections on four cases. Surg Endosc 13 1170–1171 Occurrence Handle10.1007/s004649901214 Occurrence Handle10556466

    Article  PubMed  Google Scholar 

  2. HO Douglass Jr SY Kim NJ Merpol (1997) Neoplasms of the gallbladder. JF Holland E Frei III RC Best Jr (Eds) Cancer medicine. Lippincott, Williams and Wilkins Baltimore, MD 1955–1963

    Google Scholar 

  3. D Frauenschuh R Greim E Kraas (2000) ArticleTitleHow to proceed in patients with carcinoma detected after laparoscopic cholecystectomy. Langenbeck’s Arch Surg . .

    Google Scholar 

  4. EE Frezza I Mezghebe (1997) ArticleTitleGallbladder carcinoma: 28-year experience. Int Surg 82 295–300 Occurrence Handle1:STN:280:DyaK1c%2FjvFKntQ%3D%3D Occurrence Handle9372378

    CAS  PubMed  Google Scholar 

  5. S Gentilli CM Fronticelli A Ferrero F Quiriconi R Corradino (1996) ArticleTitleGallbladder carcinoma: our experience. Minerva Chir 51 183–186 Occurrence Handle1:STN:280:BymA2sfhvVI%3D Occurrence Handle8927266

    CAS  PubMed  Google Scholar 

  6. VK Kapoor (2001) ArticleTitleIncidental gallbladder cancer. Am J Gastroenterol 96 627–629 Occurrence Handle10.1016/S0002-9270(00)02390-X Occurrence Handle1:STN:280:DC%2BD3M7ovFOmug%3D%3D Occurrence Handle11280526

    Article  CAS  PubMed  Google Scholar 

  7. O Lundberg A Kristoffersson (2001) ArticleTitleOpen versus laparoscopic cholecystectomy for gallbladder carcinoma. J Hepatobiliary Pancreat Surg 8 525–529 Occurrence Handle10.1007/s005340100020 Occurrence Handle1:STN:280:DC%2BD383hslGitQ%3D%3D Occurrence Handle11956903

    Article  CAS  PubMed  Google Scholar 

  8. InstitutionalAuthorNameNational Institutes of Health (1992) ArticleTitleGallstones and laparoscopic cholecystectomy. NIH Consens Statement 10 1–20

    Google Scholar 

  9. DB Pearlstone SA Curley BW Feig (1998) ArticleTitleThe management of gallbladder cancer: before, during, and after laparoscopic cholecystectomy. Semin Laparosc Surg 5 121–128 Occurrence Handle1:STN:280:DyaK1c3lvFSqtA%3D%3D Occurrence Handle9594039

    CAS  PubMed  Google Scholar 

  10. L Sarli C Pavlidis R Costi S Contini G Sgobba L Roncoroni (2000) ArticleTitleVideolaparoscopy and carcinoma of the gallbladder. Chir Ital 52 655–661 Occurrence Handle1:STN:280:DC%2BD3M7gvVWrtQ%3D%3D Occurrence Handle11200000

    CAS  PubMed  Google Scholar 

  11. K Suzuki T Kimura H Ogawa (1998) ArticleTitleIs laparoscopic cholecystectomy hazardous for gallbladder cancer? Surgery 123 311–314 Occurrence Handle10.1067/msy.1998.85938 Occurrence Handle1:STN:280:DyaK1c7oslaksw%3D%3D Occurrence Handle9526523

    Article  CAS  PubMed  Google Scholar 

  12. A Wysocki (2000) ArticleTitleGallbladder cancer in the age of laparoscopic surgery. Pol Merkuriusz Lek 9 729–731 Occurrence Handle1:STN:280:DC%2BD3M%2FptV2gtg%3D%3D Occurrence Handle11144069

    CAS  PubMed  Google Scholar 

  13. T Yamada DH Alpers L Laine (1999) Textbook of Gastroenterology. Williams & Wilkins Baltimore, MD

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of General Surgery, General Hospital Varazdin, I.Mestrovica bb, 42000 Varazdin, Croatia

    N. Darabos & R. Stare

Authors
  1. N. Darabos
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Stare
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Darabos, N., Stare, R. Gallbladder cancer: laparoscopic and classic cholecystectomy . Surg Endosc 18, 144–147 (2004). https://doi.org/10.1007/s00464-002-9269-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00464-002-9269-9

Keywords

Search

Navigation