Abstract
This study was conducted to evaluate the hematological and serum biochemical parameters of growing New Zealand White (NZW) rabbits administered Panax ginseng extracts (PGEs). A total of 48 NZW growing male (M) and female (F) rabbits (24 each) were used and the experiment lasted for 28 days. It was carried out in a randomized complete block design (RCBD), made up of T1 (0.0 mg/ml of PGEs), T2 (200.0 mg/ml of PGEs), and T3 (400.0 mg/ml of PGEs) which was replicated thrice and sex served as the block. Packed cell volume (PCV) (34.03%), red blood cell (RBC) (5.52 × 106/μl), white blood cell (WBC) (7.60 × 103/μl), and heterophil (34.00%) counts of the growing male NZW rabbits were significantly (P < 0.05) higher in MT3 rabbits. PGEs positively affected mean corpuscular volume (MCV) of the male rabbits which recorded a significantly (P < 0.05) higher value in MT3 (400.0 mg/ml of PGEs), but negatively affected the female rabbits which recorded a significantly (P < 0.05) higher value in FT1 (0.0 mg/ml of PGEs). Total protein values were significantly (P < 0.05) different among the experimental rabbits, with the lowest value obtained from FT3 (4.58 g/dl) rabbits. Globulin values of the rabbits were significantly (P < 0.05) lower in MT3 and FT3 rabbits. Serum cholesterol of the experimental rabbits were significantly (P < 0.05) lower in PGE-treated rabbits (MT2, MT3, FT2, and FT3). Alkaline phosphatase (ALP), alanine transaminase (ALT), and aspartate transaminase (AST) values of the growing female NZW rabbits were significantly (P < 0.05) lower in PGE-treated female rabbits. The result of this study suggests improved PCV, RBC, and cellular immunity in growing male NZW rabbits. It also suggests that PGEs have an anti-cholesterolemic effect on both male and female growing NZW rabbits.
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This study was funded by Tertiary Education Trust Fund; through Federal University of Technology Owerri (Ref: FUT/DVC (Acad.)/GEN 92/51).
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Iwuji, T.C., Herbert, U., Oguike, M.A. et al. Hematology and serum biochemistry of growing New Zealand White (NZW) rabbits administered Panax ginseng extracts. Comp Clin Pathol 27, 1691–1697 (2018). https://doi.org/10.1007/s00580-018-2795-1
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DOI: https://doi.org/10.1007/s00580-018-2795-1