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Testicular Mixed Germ Cell Tumor With Polyembryoma Component in Brothers

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Pediatric and Developmental Pathology

Abstract

We report the case of a 17-year-old male with a testicular tumor and high serum levels of α-fetoprotein. The patient was treated with surgery followed by combination chemotherapy with bleomycin, etoposide, and cisplatin. Histologic examination showed features of a mixed germ cell tumor composed of mature teratoma, immature teratoma, embryonal carcinoma, yolk sac tumor, and polyembryoma. He is currently well, and his serum levels of α-fetoprotein have been normal more than 5 months after treatment. His brother, aged 17 years at the time, had a similar tumor removed from the right testicle 5 years previously.

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Authors and Affiliations

  1. Department of Pathology, Kahramanmaras Sutcuimam University Medical School, 46050, Kahramanmaras, Turkey

    Sevgi Bakarı ıs

  2. Department of Urology, Kahramanmaras Sutcuimam University Medical School, 46050, Kahramanmaras, Turkey

    Sefa Resı ım

  3. Department of Pathology, Cukurova University Medical School, 01330, Balcalı ı, Adana, Turkey

    Nurdan Tunalı ı

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  1. Sevgi Bakarı ıs
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  2. Sefa Resı ım
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Correspondence to Sevgi Bakarı ıs.

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Bakarı ıs, S., Resı ım, S. & Tunalı ı, N. Testicular Mixed Germ Cell Tumor With Polyembryoma Component in Brothers. Pediatr Dev Pathol 8, 92–97 (2005). https://doi.org/10.1007/s10024-004-2123-4

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