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Cyclic vomiting syndrome: epidemiology, diagnosis, and treatment

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Abstract

Cyclic-vomiting syndrome (CVS) is a chronic functional gastrointestinal disorder characterized by recurrent episodes of nausea and vomiting. Although once thought to be a pediatric disorder, there has been a considerable increase in recognition of CVS in adults. The exact pathogenesis is unknown and several theories have been proposed. Migraine and CVS share a similar pathophysiology as suggested by several studies. Since there are no specific biomarkers available for this disorder, physicians should rely on Rome criteria for the diagnosis. Due to the lack of randomized control trials, the treatment of CVS is primarily empirical.

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Authors and Affiliations

  1. Division of General Internal Medicine, Medical College of Wisconsin, Milwaukee, WI, USA

    Sanjay Bhandari & Pinky Jha

  2. Quinnipiac University Frank H. Netter MD School of Medicine, North Haven, CT, USA

    Abhishek Thakur

  3. Medical College of Wisconsin, Wisconsin, WI, USA

    Abhipsa Kar & Harrison Gerdes

  4. Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI, USA

    Thangam Venkatesan

  5. Division of General Internal Medicine, Clinical Cancer Center, Medical College of Wisconsin, 9200 W Wisconsin Ave, 5th Floor, Milwaukee, WI, 53226, USA

    Sanjay Bhandari

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  1. Sanjay Bhandari
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  2. Pinky Jha
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Correspondence to Sanjay Bhandari.

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Bhandari, S., Jha, P., Thakur, A. et al. Cyclic vomiting syndrome: epidemiology, diagnosis, and treatment. Clin Auton Res 28, 203–209 (2018). https://doi.org/10.1007/s10286-018-0506-2

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  • DOI: https://doi.org/10.1007/s10286-018-0506-2

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