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Preferences for HIV Preexposure Prophylaxis Products Among Black Women in the U.S.

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Abstract

In a nationwide sample of Black women in the U.S., we assessed preferences for HIV preexposure prophylaxis (PrEP) products, including long-acting injectable (LAI) PrEP and once-daily oral PrEP. Among 315 respondents, 32.1% were aware of PrEP and 40.6% were interested in using it; interest increased to 62.2% if PrEP were provided for free. Oral PrEP was the preferred option (51.1%), followed by LAI PrEP (25.7%), vaginal gel (16.5%), and vaginal ring (6.7%). When examining oral and LAI PrEP alone, most (62.7%) preferred oral PrEP. LAI PrEP was more likely to be preferred among respondents with concerns about healthcare costs or PrEP-related stigma, and among those who reported inconsistent condom use and multiple sexual partners. Although most Black women preferred oral PrEP, LAI PrEP may be appealing to a subset with social and structural barriers to PrEP use, such as cost and stigma, and those at increased risk of HIV infection.

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Data Availability

The data that support the findings of this study are available from the corresponding author, Whitney Irie, upon reasonable request.

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Funding

This publication was made possible by Grant Numbers T32 AI007433 from the National Institute of Allergy and Infectious Diseases, T32 DA15035 from the National Institute on Drug Abuse, R25 MH08362 from the National Institute on Mental Health, and the National Association for Social Workers (NASW) Foundation’s Jane B Aron Dissertation Award to Whitney Irie. Elvin Geng is supported by Grant Number K24 AI134413 from the National Institute of Allergy and Infectious Diseases. This publication’s contents are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health or the NASW.

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Authors and Affiliations

  1. Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA

    Whitney C. Irie & Julia L. Marcus

  2. Department of Psychological and Brain Sciences, George Washington University, Washington, DC, USA

    Sarah K. Calabrese

  3. Department of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA

    Sarah K. Calabrese

  4. Division of Infectious Diseases, Washington University in St Louis, St. Louis, MO, USA

    Rupa R. Patel & Elvin H. Geng

  5. The Fenway Institute, Fenway Health, Boston, MA, USA

    Kenneth H. Mayer & Julia L. Marcus

  6. Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA

    Kenneth H. Mayer

  7. Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Dr, Ste 401, Boston, MA, 02215, USA

    Whitney C. Irie

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Contributions

Material preparation, data collection, and analysis were performed by WI. The first draft of the manuscript was written by WI. Manuscript drafting, review, and editing was completed by JM, and all authors provided critical input on previous versions of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Whitney C. Irie.

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Conflict of interest

Dr. Calabrese received partial support from Gilead for conference attendance in 2019 unrelated to this work. Dr. Marcus previously consulted for Kaiser Permanente Northern California on a research grant from Gilead Sciences unrelated to the submitted work. Dr. Mayer has received unrestricted educational grants from Gilead Sciences and served on a scientific advisory board for them unrelated to this work. Dr. Geng has received an educational grant from Viiv Healthcare. All other authors declare no conflicts.

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All procedures performed in this study were in accordance with the ethical standards of the Institutional Review Board at Washington University in St. Louis. (IRB201902109) and with the 1964 Helsinki Declaration and its later amendments.

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Informed consent was obtained from all individual participants included in the study.

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Irie, W.C., Calabrese, S.K., Patel, R.R. et al. Preferences for HIV Preexposure Prophylaxis Products Among Black Women in the U.S.. AIDS Behav 26, 2212–2223 (2022). https://doi.org/10.1007/s10461-021-03571-8

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