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Cellulose/biopolymer/Fe3O4 hydrogel microbeads for dye and protein adsorption

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Abstract

Cellulose-based magnetic hydrogel microbeads were prepared through sol–gel transition using a 1-ethyl-3-methylimidazolium acetate-in-oil emulsion. Surface properties of the microbeads were altered by blending cellulose with chitosan, carrageenan, lignin, or starch. The adsorption capacity of the cellulose microbeads for crystal violet was 1.3 times higher after blending cellulose with carrageenan, while that for methyl orange was 2.0 times higher after blending cellulose with chitosan. As a model study, kinetics and isotherms for the adsorption of crystal violet on the cellulose/carrageenan microbeads were investigated to understand the effect of the biopolymer on the adsorption properties. Adsorption capacities of the cellulose microbeads for pepsin and bovine serum albumin were 1.6 and 1.2 times higher after blending cellulose with chitosan, respectively. The adsorption capacity of the cellulose/carrageenan microbeads for lysozyme was 1.2 times higher than that of the cellulose microbeads. The cellulose/alkali lignin and cellulose/starch magnetic microbeads were found to be efficient supports for immobilization of lipase. Specific activities of lipase immobilized on the cellulose/alkali lignin and cellulose/starch magnetic microbeads were 1.2- and 1.4-fold higher than that of free lipase, respectively. Under denaturing thermal conditions, the half-life of lipase immobilized on the cellulose/alkali lignin and cellulose/starch magnetic microbeads was 47- and 56-fold higher than that of free lipase, respectively. Thus, owing to their biocompatibility, biodegradability, and controllability, the cellulose/biopolymer/Fe3O4 hydrogel microbeads may have many potential applications in biocatalytic, biomedical, and environmental fields.

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Acknowledgments

This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education [Grant Number: 2018R1D1A1B07050163], and by the Technology Development Program to Solve Climate Changes of the NRF, funded by the Ministry of Science and ICT [Grant Numbers: 2017M1A2A2087627 and 2017M1A2A2087647]. This work was also supported by research grant from the Ministry of Trade, Industry and Energy through the Korean Evaluation Institute of Industrial Technology [Grant Number: 20002810].

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Authors and Affiliations

  1. Department of Biological Engineering, Konkuk University, Seoul, 05029, South Korea

    Saerom Park, Yujin Oh, Jeongchel Yun, Eunjin Yoo, Dahun Jung & Sang Hyun Lee

  2. Department of Chemical Engineering, Dankook University, Yongin, Gyeonggi-do, 16890, South Korea

    Kyeong Keun Oh

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  1. Saerom Park
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  2. Yujin Oh
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  4. Eunjin Yoo
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Correspondence to Sang Hyun Lee.

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Park, S., Oh, Y., Yun, J. et al. Cellulose/biopolymer/Fe3O4 hydrogel microbeads for dye and protein adsorption. Cellulose 27, 2757–2773 (2020). https://doi.org/10.1007/s10570-020-02974-5

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