A new phenanthrene, 2,6-dihydroxy-5,8-dimethoxyphenanthrene (1), was isolated from Pleione praecox. The structure of the new compound was determined on the basis of NMR (1D and 2D) and HR-ESI-MS data. The new compound was also evaluated for its α-glucosidase inhibitory activity. Compared with the positive control acarbose, the new compound exhibited appreciable effect.
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Acknowledgment
The research work was supported by the Program Innovative Research Team in Science and Technology in Yunnan Province (202005AE160004), Yunnan Provincial Science and the Technology Department (202005AF150043) and Foundation of Yunling Scholars in Yunnan Province (2019), the National Natural Science Foundation of China (21202066) and the Applied Basic Research Program of Yunnan Province [2017FE468(-025)], PhD student innovation fund Project (2021) and the Project for Excellent Young Teacher of Kunming Medical University (Nos. J130130661, 60118090145, 70120030505, and 6011521120).
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2021, pp. 349–350.
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Li, YP., Shao, YT. & Zhang, RP. A New Phenanthrene Derivative from Pleione praecox. Chem Nat Compd 57, 409–411 (2021). https://doi.org/10.1007/s10600-021-03375-1
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DOI: https://doi.org/10.1007/s10600-021-03375-1