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Rapid oxidation of alcohols to aldehydes and ketones with chromium trioxide catalyzed by kieselguhr under solvent-free conditions

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Abstract

A rapid and selective oxidation of alcohols to aldehydes and ketones with chromium trioxide catalyzed by kieselguhr under solvent-free conditions in yields between 90 and 98 % is described. The role of kieselguhr in this oxidation is not only as support but also as catalyst, even though the catalytic nature of the kieselguhr is currently unclear. The present oxidation is even faster than (or the same as) those assisted with microwave irradiations. Meanwhile, the influence of the water presence during the preparation of the reagent is considered.

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Authors and Affiliations

  1. College of Life Sciences, China Jiliang University, Hangzhou, 310018, Zhejiang, China

    Ai He, Jie Zhang, Wenjin Zheng, Lihong Huang & Ji-Dong Lou

  2. China Pharmaceutical University, Nanjing, 210009, Jiangsu, China

    Chen Huang

  3. Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB)/Department of Biology and Environment, Universidade de Trás-os-Montes e Alto Douro (UTAD), Apartado 1013, 5001-801, Vila Real, Portugal

    Changhe Zhang

  4. Sirnaomics, Inc., 401 Professional Drive, Gaithersburg, MD, 20879, USA

    Ji-Dong Lou

Authors
  1. Ai He
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  2. Jie Zhang
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  3. Wenjin Zheng
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  4. Chen Huang
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  5. Changhe Zhang
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  6. Lihong Huang
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  7. Ji-Dong Lou
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Correspondence to Ji-Dong Lou.

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He, A., Zhang, J., Zheng, W. et al. Rapid oxidation of alcohols to aldehydes and ketones with chromium trioxide catalyzed by kieselguhr under solvent-free conditions. Res Chem Intermed 39, 1015–1020 (2013). https://doi.org/10.1007/s11164-012-0663-1

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  • DOI: https://doi.org/10.1007/s11164-012-0663-1

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