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Relationship between dental calcification of mandibular teeth and cervical vertebrae maturity in patients with unilateral complete cleft lip and palate

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Abstract

Objective

The purpose of this study was to investigate the relationship between the dental calcification stage (DCS) of the mandibular teeth and the cervical vertebral maturation stage (CVMS) in patients with unilateral complete cleft lip and palate (UCLP).

Methods

One hundred sixty-two UCLP patients (100 males and 62 females) between 8–16 years old were included in this study. The DCS was estimated by the Demirjian method and was converted to the dental age (DA). The CVMS was evaluated by the Baccetti method. The DA of mandibular teeth on two sides of the cleft were analyzed using a t-test. Spearman correlation was used to study the association between CVMS and DCS. The correlation coefficient between the two sides of the cleft was then compared.

Results

The total DA was significantly smaller on the cleft side than on the noncleft side in males (p = 0.022). The Spearman rank correlation coefficient revealed a significant correlation between the DCS of each examined tooth and the CVMS (r = 0.627–0.793 in males and r = 0.806–0.899 in females). Additionally, the correlation of the two sides was not significantly different (p > 0.05). The DCS of the first premolar showed the strongest correlation with the CVMS.

Conclusion

The results confirm the utility of the DCS on both sides of the mandible in male UCLP patients as a simple first-level diagnostic test to evaluate growth and development. The findings also indicate that both the DCS and the CVMS should be assessed if the maturity stage of a growing UCLP patient is relevant to clinical practice.

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Acknowledgements

This work was supported by the Shandong Province Science and Technology Development Program [2014GGH218012] of the Department of Science and Technology of Shandong Province. And we would like to acknowledge their assistance. In addition, we would like to thank “American Journal Experts” for their language assistance.

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Authors and Affiliations

  1. Department of Orthodontics, The Affiliated Hospital of Qingdao University, No. 16, Jiangsu Road, Qingdao, 266000, Shandong, China

    Xiaoxu Fang, Cunhui Fan, Chunmiao Jiang, Xu Tao, Zhonghui Tian & Xiaolin Xu

  2. School of Stomatology, Qingdao University, No. 19, Jiangsu Road, Qingdao, 266003, Shandong, China

    Xiaoxu Fang, Cunhui Fan, Chunmiao Jiang, Xu Tao, Zhonghui Tian & Xiaolin Xu

  3. Department of Orthodontics, The Affiliated Hospital of Taishan Medical University, Tai’an, Shandong, People’s Republic of China

    Qing Xue

  4. Department of Oral Surgery, The Affiliated Hospital of Qingdao University, Oral Medicine Center of Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China

    Wenlin Xiao

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  1. Xiaoxu Fang
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Correspondence to Cunhui Fan.

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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. This article does not contain any animal studies performed by any of the authors.

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Fang, X., Fan, C., Jiang, C. et al. Relationship between dental calcification of mandibular teeth and cervical vertebrae maturity in patients with unilateral complete cleft lip and palate. Oral Radiol 37, 209–217 (2021). https://doi.org/10.1007/s11282-020-00433-2

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  • DOI: https://doi.org/10.1007/s11282-020-00433-2

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