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Malignant solitary fibrous tumor of the pleura: computed tomography-pathological correlation and comparison with computed tomography of benign solitary fibrous tumor of the pleura

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Abstract

Purpose

The aim of this study was to determine the computed tomography (CT)-pathological correlation of malignant solitary fibrous tumors of the pleura (MSFP) and to compare these findings with CT findings of benign solitary fibrous tumors of the pleura (BSFTP).

Materials and methods

We retrospectively identified the clinical, CT, and pathological findings in seven cases of MSFP. There was a CT-pathological correlation for the MSFPs. Additionally, 12 cases of BSFTP from case files were compared with the clinical and CT features of the MSFPs.

Results

On CT, the MSFP appeared as a heterogeneously enhancing mass >10 cm (100%). Pleural metastasis (57.1%) and lung metastasis (14.3%) were associated. In the CT-pathological correlation, the enhancing area was mixed cellular and collagenous tissue with hypercellularity, mitosis, and pleomorphism. Hemorrhage, necrosis, cystic, or myxoid degeneration produced areas of intratumoral low attenuation. MSFPs showed a higher incidence of intratumoral low-attenuation areas (P = 0.034) and pleural metastasis (P = 0.009); and on CT, MSFPs tended to be larger than BSFTPs (P = 0.076).

Conclusion

MSFPs showed a >10 cm pleural mass with low-attenuation regions on CT, which corresponded to hemorrhage, necrosis, cystic, or myxoid degeneration. MSFPs had a higher incidence of intratumoral lowattenuation areas and pleural metastasis, and on CT they tended to be larger than BSFTPs.

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Authors and Affiliations

  1. Department of Radiology, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Gyeonggi, Korea

    Sun Wha Song

  2. Department of Radiology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Seocho-gu, Seoul, 137-701, Korea

    Jung Im Jung & Seog Hee Park

  3. Department of Pathology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

    Kyo Young Lee

  4. Kim Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea

    Mi-Young Kim

Authors
  1. Sun Wha Song
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  2. Jung Im Jung
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  3. Kyo Young Lee
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  4. Mi-Young Kim
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  5. Seog Hee Park
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Correspondence to Jung Im Jung.

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Song, S.W., Jung, J.I., Lee, K.Y. et al. Malignant solitary fibrous tumor of the pleura: computed tomography-pathological correlation and comparison with computed tomography of benign solitary fibrous tumor of the pleura. Jpn J Radiol 28, 602–608 (2010). https://doi.org/10.1007/s11604-010-0484-3

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  • DOI: https://doi.org/10.1007/s11604-010-0484-3

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