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Composite Length of Stay, An Outcome Measure of Postoperative and Readmission Length of Stays in Pancreatoduodenectomy

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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Purpose

Postoperative length of stay (PLOS) and readmission rate are pancreatoduodenectomy (PD) outcome measures, which are reported individually but may be interrelated. The purpose of this study was to evaluate how well a composite length of stay measure (CLOS) that included PLOS and readmission length of stay describes outcomes. To do so, we evaluated how well CLOS correlated to postoperative complications absolutely and compared to PLOS.

Methods

A total of 668 PDs performed between 2011 and 2018 were evaluated. CLOS was calculated from PLOS and readmission length of stay. Complication severity was judged by the Modified Accordion Grading System (MAGS). Multinomial logistical regression models (MLRM) were used to investigate the relationship between either PLOS or CLOS and complications. Multilevel and pairwise area under curves (AUC) using SAS macro %MultAUC were provided for both models.

Results

A total of 432 of 668 patients (65%) developed complications. One hundred seventy-seven patients (27%) were readmitted. Mean PLOS was 10.2 days (7.1 SD) and mean CLOS was 12.3 days (10.1 SD). PLOS and CLOS both were correlated linearly to MAGS grade. Spearman correlation coefficient for CLOS vs. MAGS of 0.68 was higher than that of 0.49 for PLOS vs. MAGS. Multilevel AUC from MLRM using PLOS was 0.66, but multilevel AUC from MLRM using CLOS was 0.71.

Discussion

CLOS provides an accurate estimate of hospital day utilization per patient for PD, reflecting not only the basal hospital recovery time for PD but the added time needed because of readmissions due to complications. It is tightly correlated to number and severity of postoperative complications.

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Funding

This work is supported by the SPORE Grant 5P50 CA196510 (G.A.W., J.L.). REDCap is supported by Clinical and Translational Science Award (CTSA) grant UL1 TR000449 and Siteman Comprehensive Cancer Center and NCI Cancer Center Support Grant P30 CA091842.

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Authors and Affiliations

  1. Section of Hepato-Pancreato-Biliary Surgery, Department of Surgery, Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, Saint Louis, MO, USA

    Gregory A. Williams, William G. Hawkins, Dominic E. Sanford, Chet W. Hammill & Steven M. Strasberg

  2. Division of Public Health Sciences, Department of Surgery, Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, Saint Louis, MO, USA

    Jingxia Liu

  3. Section of Transplant Surgery, Department of Surgery, Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, Saint Louis, MO, USA

    William C. Chapman, Majella B. Doyle & Adeel S. Khan

  4. Section of Surgical Oncology, Department of Surgery, Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, Saint Louis, MO, USA

    Ryan C. Fields

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  1. Gregory A. Williams
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  2. Jingxia Liu
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  3. William C. Chapman
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  4. William G. Hawkins
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  5. Ryan C. Fields
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  6. Dominic E. Sanford
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  7. Majella B. Doyle
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  8. Chet W. Hammill
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  9. Adeel S. Khan
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  10. Steven M. Strasberg
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Contributions

G.A.W., J.L., participated in study conception and design, analysis, and drafting of the article.

G.A.W., J.L., W.C.C., W.G.H., R.C.F., D.E.S., M.B.D., C.W.H., A.S.K., participated in acquisition of data, analysis, and interpretation of data.

S.M.S. participated in study conception and design, acquisition of data, analysis, and interpretation of data and critical revision of the manuscript.

Corresponding author

Correspondence to Steven M. Strasberg.

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The authors declare that they have no conflict(s) of interest.

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Williams, G.A., Liu, J., Chapman, W.C. et al. Composite Length of Stay, An Outcome Measure of Postoperative and Readmission Length of Stays in Pancreatoduodenectomy. J Gastrointest Surg 24, 2062–2069 (2020). https://doi.org/10.1007/s11605-019-04475-8

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  • DOI: https://doi.org/10.1007/s11605-019-04475-8

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