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Biogenic Silver Nanoparticles: Evaluation of Their Biological and Catalytic Potential

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Indian Journal of Microbiology Aims and scope Submit manuscript

Abstract

The biogenic tailoring of silver nanoparticles using plant extract is becoming an attractive approach in the current scenario. Manilkara zapota (MZ) is well known for its antibacterial, hepato-protective, anti-inflammatory, anti-tussive, anti-fungal, anti-tumour, and free radical scavenging potential. Its plants extract is a rich source of secondary metabolites. Nowadays, silver nanoparticles (AgNPs) have been advocated for a variety of biomedical applications. In present work, silver nanoparticles have been synthesized using an aqueous extract of MZ, physicochemically characterized and finally evaluated for antimicrobial effects, catalytic reduction/degradation of organic dyes and cytotoxicity. The nanosized AgNPs (~ 84 nm) were found to possess prominent antibacterial potential against gram positive and gram negative pathogens (MIC 50 μg/ml) in comparison to native plant extract. Moreover, these particles were found to be non-toxic and efficient eradicators of environmental toxicants via rapid catalytic reduction of toxic chemicals and dyes. Altogether, these results suggest promising potential of these nanoparticles that can be used as multifunctional agents for future biomedical applications.

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Acknowledgement

IS wishes to acknowledge Department of Science and Technology, New Delhi for awarding DST-INSPIRE to carry out this work. The authors also thank IITR-Lucknow and USIC-DU for TEM, XRD, Raman and SEM facility, respectively.

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Authors and Affiliations

  1. CSIR-Institute of Genomics and Integrative Biology, North Campus, Mall Road, Delhi, Delhi, 110007, India

    Bhawna Sharma & Pradeep Kumar

  2. CSIR-Institute of Genomics and Integrative Biology, South Campus, Mathura Road, New Delhi, Delhi, 110020, India

    Indu Singh & Hemant Gautam

  3. Acharya Narendra Dev College, University of Delhi, Govindpuri, Kalkaji, New Delhi, 110019, India

    Indu Singh & Seema Gupta

  4. Department of Environmental Sciences, J.C. Bose University of Science and Technology, YMCA, Faridabad, Haryana, 121006, India

    Bhawna Sharma & Somvir Bajar

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  1. Bhawna Sharma
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  2. Indu Singh
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Sharma, B., Singh, I., Bajar, S. et al. Biogenic Silver Nanoparticles: Evaluation of Their Biological and Catalytic Potential. Indian J Microbiol 60, 468–474 (2020). https://doi.org/10.1007/s12088-020-00889-0

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  • DOI: https://doi.org/10.1007/s12088-020-00889-0

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