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Baculovirus host-range

  • Published:
Virologica Sinica

Abstract

Baculoviruses are used as microbial insecticides, protein expression vectors, epitope display platforms, and most recently as vectors for gene therapy. Understanding the mechanisms that control baculovirus host-range and tissue tropisms are important for assessing their safety and for improving their properties for these biotechnology applications. In the past two decades some progress has been made and several baculovirus genes that influence host-range have been identified. Despite this progress, our understanding of the underlying mechanisms that restrict baculovirus host-range is still limited. Here we review what is currently known about baculovirus genes that influence virus host-range.

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References

  1. Albert T K, Hanzawa H, Legtenberg Y I A, et al. 2002. Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex. Embo J, 21(3): 355–364.

    PubMed  CAS  Google Scholar 

  2. Argaud O, Croizier L, Lopez-Ferber M, et al. 1998. Two key mutations in the host-range specificity domain of the p143 gene of Autographa californica nucleopolyhedrovirus are required to kill Bombyx mori larvae. J Gen Virol, 79: 931–935.

    PubMed  CAS  Google Scholar 

  3. Benz G A. 1986. Introduction: Historical perspectives. In: The biology of baculoviruses (Granados R R, Federici B A, ed.), vol.1. Biological properties and molecular biology. Boca Raton: CRC Press.

    Google Scholar 

  4. Bernardi R, Pandolfi P P. 2007. Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies. Nat Rev Mol Cell Biol, 8(12): 1006–1016.

    PubMed  CAS  Google Scholar 

  5. Berretta M F, Deshpande M, Crouch E A, et al. 2006. Functional characterization of Bombyx mori nucleopolyhedrovirus late gene transcription and genome replication factors in the non-permissive insect cell line SF-21. Virology, 348(1): 175–189.

    PubMed  CAS  Google Scholar 

  6. Bertin J, Mendrysa S M, LaCount D J, et al. 1996. Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease. J Virol, 70(9): 6251–6259.

    PubMed  CAS  Google Scholar 

  7. Black B C, Brennan L A, Dierks P M, et al. 1997. Commercialization of baculovirus insecticides, p. 341–387. In: The Baculoviruses (Miller L K,ed.), New York: Plenum Press.

    Google Scholar 

  8. Blissard G W. 1996. Baculovirus-insect cell interactions. Cytotechnology, 20(1–3): 73–93.

    PubMed  CAS  Google Scholar 

  9. Blissard G W, Wenz J R. 1992. Baculovirus gp64 envelope glycoprotein is sufficient to mediate pH-dependent membrane-fusion. J Virol, 66(11): 6829–6835.

    PubMed  CAS  Google Scholar 

  10. Borden K L B. 2000. RING domains: Master builders of molecular scaffolds? J Mol Biol, 295(5): 1103–1112.

    PubMed  CAS  Google Scholar 

  11. Boyce F M, Bucher N L R. 1996. Baculovirus-mediated gene transfer into mammalian cells. Proc Natl Acad Sci U S A, 93(6): 2348–2352.

    PubMed  CAS  Google Scholar 

  12. Carson D D, Guarino L A, Summers M D. 1988. Functional mapping of an AcNPV immediately early gene which augments expression of the ie-1 transactivated 39k-gene. Virology, 162(2): 444–451.

    PubMed  CAS  Google Scholar 

  13. Chen C J, Quentin M E, Brennan L A, et al. 1998. Lymantria dispar nucleopolyhedrovirus hrf-1 expands the larval host range of Autographa californica nucleopolyhedrovirus. J Virol, 72(3): 2526–2531.

    PubMed  CAS  Google Scholar 

  14. Chen C J, Thiem S M. 1997. Differential infectivity of two Autographa californica nucleopolyhedrovirus mutants on three permissive cell lines is the result of lef-7 deletion. Virology, 227(1): 88–95.

    PubMed  CAS  Google Scholar 

  15. Cheng T C, Zhang Y L, Liu C, et al. 2008. Identification and analysis of Toll-related genes in the domesticated silkworm, Bombyx mori. Dev Comp Immunol, 32(5): 464–475.

    PubMed  CAS  Google Scholar 

  16. Cheng X-W, Lynn D E. 2009. Virus-virus interaction in vitro and in vivo. Adv Appl Microbiol, 68:218–239.

    Google Scholar 

  17. Cheng X W, Carner G K, Lange M, et al. 2005. Biological and molecular characterization of a multicapsid nueleopolyhedrovirus from Thysanoplusia orichalcea (L.) (Lepidoptera: Noctuidae). J Invertebr Pathol, 88(2): 126–135.

    PubMed  CAS  Google Scholar 

  18. Clarke T E, Clem R J. 2003. In vivo induction of apoptosis correlating with reduced infectivity during baculovirus infection. J Virol, 77(3): 2227–2232.

    PubMed  CAS  Google Scholar 

  19. Clem R J. 2007. Baculoviruses and apoptosis: A diversity of genes and responses. Current Drug Targets, 8(10): 1069–1074.

    PubMed  CAS  Google Scholar 

  20. Clem R J, Fechheimer M, Miller L K. 1991. Prevention of apoptosis by a baculovirus gene during infection of insect cells. Science, 254(5036): 1388–1390.

    PubMed  CAS  Google Scholar 

  21. Clem R J, Miller L K. 1993. Apoptosis reduces both the invitro replication and the invivo infectivity of a baculovirus. J Virol, 67(7): 3730–3738.

    PubMed  CAS  Google Scholar 

  22. Clem R J, Robson M, Miller L K. 1994. Influence of infection route on the infectivity of baculovirus mutants lacking the apoptosis-inhibiting gene P35 and the adjacent gene P94. J Virol, 68(10): 6759–6762.

    PubMed  CAS  Google Scholar 

  23. Condreay J P, Kost T A. 2007. Baculovirus expression vectors for insect and mammalian cells. Curr Drug Targets, 8:1126–1131.

    PubMed  CAS  Google Scholar 

  24. Croizier G, Croizier L, Argaud O, et al. 1994. Extension of Autographa-californica nuclear polyhedrosisvirus host-range by interspecific replacement of a short DNA-sequence in the P143 helicase gene. Proc Natl Acad Sci USA, 91(1): 48–52.

    PubMed  CAS  Google Scholar 

  25. Crook N E, Clem R J, Miller L K. 1993. An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif. J Virol, 67(4): 2168–2174.

    PubMed  CAS  Google Scholar 

  26. Doyle C J, Hirst M L, Cory J S, et al. 1990. Risk assessment studies-Detailed host range testing of wild-type cabbage moth, Mamestra-Brassicae (Lepidoptera, Noctuidae), Nuclear Polyhedrosis-Virus. Appl Environ Microbiol, 56(9): 2704–2710.

    PubMed  Google Scholar 

  27. Du Q S, Lehavi D, Faktor O, et al. 1999. Isolation of an apoptosis suppressor gene of the Spodoptera littoralis nucleopolyhedrovirus. J Virol, 73(2): 1278–1285.

    PubMed  CAS  Google Scholar 

  28. Du X L, Thiem S M. 1997. Characterization of host range factor 1 (hrf-1) expression in Lymantria dispar M nucleopolyhedrovirus-and recombinant Autographa californica M nucleopolyhedrovirus-infected IPLB- Ld652Y cells. Virology, 227(2): 420–430.

    PubMed  CAS  Google Scholar 

  29. Du X L, Thiem S M. 1997. Responses of insect cells to baculovirus infection: Protein synthesis shutdown and apoptosis. J Virol, 71(10): 7866–7872.

    PubMed  CAS  Google Scholar 

  30. Engelhard E K, Kammorgan L N W, Washburn J O, et al. 1994. The insect tracheal system — a conduit for the systemic spread of Autographa-californica-M nuclear polyhedrosis-virus. Proc Natl Acad Sci USA, 91(8): 3224–3227.

    PubMed  CAS  Google Scholar 

  31. Everett R D, Chelbi-Alix M K. 2007. PML and PML nuclear bodies: Implications in antiviral defence. Biochimie, 89(6–7): 819–830.

    PubMed  CAS  Google Scholar 

  32. Flipsen J T M, Martens J W M, Vanoers M M, et al. 1995. Passage of Autographa-californica nuclear polyhedrosis-virus through the midgut epithelium of Spodoptera-exigua larvae. Virology, 208(1): 328–335.

    PubMed  CAS  Google Scholar 

  33. Friesen P D. 2007. Insect Viruses, In: Fields Virology (Knipe D M, Howley P M. ed.), 5th ed, vol. 1. Philadelphia, Lippincott Williams & Wilkins. p707–736.

    Google Scholar 

  34. Funk C J, Braunagel S C, Rohrmann G F. 1997. Baculovirus structure, In: The Baculovirus (Miller L K,ed.), New York: Plenum Press. p7–32.

    Google Scholar 

  35. Gomi S, Majima K, Maeda S. 1999. Sequence analysis of the genome of Bombyx mori nucleopolyhedrovirus. J Gen Virol, 80: 1323–1337.

    PubMed  CAS  Google Scholar 

  36. Gomi S, Zhou C E, Yih W Y, et al. 1997. Deletion analysis of four of eighteen late gene expression factor gene homologues of the baculovirus, BmNPV. Virology, 230(1): 35–47.

    PubMed  CAS  Google Scholar 

  37. Goodman C L, El Sayed G N, McIntosh A H, et al. 2001. Establishment and characterization of insect cell lines from 10 lepidopteran species. In Vitro Cell Dev Biol-Anim, 37(6): 367–373.

    PubMed  CAS  Google Scholar 

  38. Goodman C L, Wang A A, Nabli H, et al. 2004. Development and partial characterization of heliothine cell lines from embryonic and differentiated tissues. In Vitro Cell Dev Biol-Anim, 40(3–4): 89–94.

    PubMed  CAS  Google Scholar 

  39. Goodwin R H, Vaughn J L, Adams J R, et al. 1970. Replication of a nuclear polyhedrosis virus in an established insect cell line. J Invertebr Pathol, 16(2): 284–288.

    PubMed  CAS  Google Scholar 

  40. Granados R R, Derksen A C G, Dwyer K G. 1986. Replication of the Trichoplusia-ni granulosis and nuclear polyhedrosis viruses in cell-cultures. Virology, 152(2): 472–476.

    PubMed  CAS  Google Scholar 

  41. Griffiths C M, Barnett A L, Ayres M D, et al. 1999. In vitro host range of Autographa californica nucleopoly-hedrovirus recombinants lacking functional p35, iap1 or iap2. J Gen Virol, 80: 1055–1066.

    PubMed  CAS  Google Scholar 

  42. Gröner A. 1986. Specificity and safety of baculoviruses, In:The biology of baculoviruses (Granados R R, Federici B A,ed.), vol. 1. Biological properties and molecular biology. Boca Raton: CRC Press. p177–202.

    Google Scholar 

  43. Guo T Q, Wang S P, Guo X Y, et al. 2005. Productive infection of Autographa californica nucleopolyhedrovirus in silkworm Bombyx mori strain Haoyue due to the absence of a host antiviral factor. Virology, 341(2): 231–237.

    PubMed  CAS  Google Scholar 

  44. Guzo D, Rathburn H, Guthrie K, et al. 1992. Viral and host cellular transcription in Autographa-californica nuclear polyhedrosis virus-infected gypsy-moth cell-lines. J Virol, 66(5): 2966–2972.

    PubMed  CAS  Google Scholar 

  45. Haas-Stapleton E J, Washburn J O, Volkman L E. 2003. Pathogenesis of Autographa californica M nucleopoly-hedrovirus in fifth instar Spodoptera frugiperda. J Gen. Virol, 84: 2033–2040.

    PubMed  CAS  Google Scholar 

  46. Haas-Stapleton E J, Washburn J O, Volkman L E. 2004. P74 mediates specific binding of Autographa californica M nucleopolyhedrovirus occlusion-derived virus to primary cellular targets in the midgut epithelia of Heliothis virescens larvae. J Virol, 78(13): 6786–6791.

    PubMed  CAS  Google Scholar 

  47. Haas-Stapleton E J, Washburn J O, Volkman L E. 2005. Spodoptera frugiperda resistance to oral infection by Autographa californica multiple nucleopolyhedrovirus linked to aberrant occlusion-derived virus binding in the midgut. J Gen Virol, 86: 1349–1355.

    PubMed  CAS  Google Scholar 

  48. Hanzawa H, de Ruwe M J, Albert T K, et al. 2001. The structure of the C4C4 RING finger of human NOT4 reveals features distinct from those of C3HC4 RING fingers. J Biol Chem, 276(13): 10185–10190.

    PubMed  CAS  Google Scholar 

  49. Harrison R L, Bonning B C. 1999. The nucleopoly-hedroviruses of Rachiplusia ou and Anagrapha falcifera are isolates of the same virus. J Gen Virol, 80: 2793–2798.

    PubMed  CAS  Google Scholar 

  50. Hedges L M, Johnson K N. 2008. Induction of host defence responses by Drosophila C virus. J Gen Virol, 89: 1497–1501.

    PubMed  CAS  Google Scholar 

  51. Hefferon K L. 2003. Characterization of HCF-1, a determinant of Autographa californica multiple nucleo-polyhedrovirus host specificity. Insect Mol Biol, 12(6): 651–658.

    PubMed  CAS  Google Scholar 

  52. Herniou E A, Olszewski J A, Cory J S, et al. 2003. The genome sequence and evolution of baculoviruses. Annu Rev Entomol, 48: 211–234.

    PubMed  CAS  Google Scholar 

  53. Hershberger P A, Dickson J A, Friesen P D. 1992. Site-specific mutagenesis of the 35-kilodalton protein gene encoded by Autographa-californica nuclear polyhedrosis-virus-cell line-specific effects on virus-replication. J Virol, 66(9): 5525–5533.

    PubMed  CAS  Google Scholar 

  54. Hink W F. 1970. Established insect cell line from cabbage looper, Trichoplusia-ni. Nature, 226(5244): 466–467.

    PubMed  CAS  Google Scholar 

  55. Horton H M, Burand J P. 1993. Saturable attachment sites for polyhedron-derived baculovirus on insect cells and evidence for entry via direct membrane-fusion. J Virol, 67(4): 1860–1868.

    PubMed  CAS  Google Scholar 

  56. Hostetter D L, Puttler B. 1991. A new broad host spectrum nuclear polyhedrosis-virus isolated from a celery looper, Anagrapha-falcifera (Kirby), (Lepidoptera, Noctuidae). Environ Entomol, 20(5): 1480–1488.

    Google Scholar 

  57. Ignoffo C M. 1968. Specificity of insect viruses. Bull Entomol Soc Am, 14: 265–276.

    Google Scholar 

  58. Ijkel W F J, Westenberg M, Goldbach R W, et al. 2000. A novel baculovirus envelope fusion protein with a proprotein convertase cleavage site. Virology, 275(1): 30–41.

    PubMed  CAS  Google Scholar 

  59. Ikeda M, Reimbold E A, Thiem S M. 2005. Functional analysis of the baculovirus host range gene, hrf-1. Virology, 332: 602–613.

    PubMed  CAS  Google Scholar 

  60. Inceoglu A B, Kamita S G, Hinton A C, et al. 2001. Recombinant baculoviruses for insect control. Pest Management Science, 57(10): 981–987.

    PubMed  CAS  Google Scholar 

  61. International Committee on Taxonomy of Viruses. 2008. Virus Taxonomy 2008. http://www.ictvonline.org/virusTaxonomy.asp?version=2008&bhcp=1.

  62. Ishikawa H, Ikeda M, Alves C A F, et al. 2004. Host range factor 1 from Lymantria dispar nucleopolyhedrovirus (NPV) is an essential viral factor required for productive infection of NPVs in IPLB-Ld652Y cells derived from L. dispar. J Virol, 78(22): 12703–12708.

    PubMed  CAS  Google Scholar 

  63. Ishikawa H, Ikeda M, Yanagimoto K, et al. 2003. Induction of apoptosis in an insect cell line, IPLB-Ld652Y, infected with nucleopolyhedroviruses. J Gen Virol, 84: 705–714.

    PubMed  CAS  Google Scholar 

  64. Ishikawa H, Ogasawara T, Ikeda M, et al. 2006. A recombinant Bombyx mori nucleopolyhedrovirus possessing hrf-1 gene replicates in nonpermissive Lymantria dispar IPLB-Ld652Y cell line. J Insect Biotechnol Sericology, 75(1): 31–38.

    CAS  Google Scholar 

  65. Iwanaga M, Takaya K, Katsuma S, et al. 2004. Expression profiling of baculovirus genes in permissive and nonpermissive cell lines. Biochem Biophys Res Commun, 323(2): 599–614.

    PubMed  CAS  Google Scholar 

  66. Jehle J A, Blissard G W, Bonning B C, et al. 2006. On the classification and nomenclature of baculoviruses: A proposal for revision. Arch Virol, 151(7): 1257–1266.

    PubMed  CAS  Google Scholar 

  67. Joazeiro C A P, Weissman A M. 2000. RING finger proteins: Mediators of ubiquitin ligase activity. Cell, 102(5): 549–552.

    PubMed  CAS  Google Scholar 

  68. Kamita S G, Maeda S. 1993. Inhibition of Bombyx-mori nuclear polyhedrosis-virus (NPV) replication by the putative DNA helicase gene of Autographa-californica NPV. J Virol, 67(10): 6239–6245.

    PubMed  CAS  Google Scholar 

  69. Kamita S G, Maeda S. 1996. Abortive infection of the baculovirus Autographa californica nuclear polyhedrosis virus in Sf-9 cells after mutation of the putative DNA helicase gene. J Virol, 70(9): 6244–6250.

    PubMed  CAS  Google Scholar 

  70. Kamita S G, Majima K, Maeda S. 1993. Identification and characterization of the P35-gene of Bombyxmori nuclear polyhedrosis-virus that prevents virus-induced apoptosis. J Virol, 67(1): 455–463.

    PubMed  CAS  Google Scholar 

  71. Katou Y, Ikeda M, Kobayashi M. 2006. Abortive replication of Bombyx mori nucleopolyhedrovirus in Sf9 and High Five cells: Defective nuclear transport of the virions. Virology, 347(2): 455–465.

    PubMed  CAS  Google Scholar 

  72. Kikhno I, Gutierrez S, Croizier L, et al. 2002. Characterization of pif, a gene required for the per os infectivity of Spodoptera littoralis nucleopolyhedrovirus. J Gen Virol, 83: 3013–3022.

    PubMed  CAS  Google Scholar 

  73. Kondo A, Maeda S. 1991. Host range expansion by recombination of the baculoviruses Bombyx-mori nuclear polyhedrosis-virus and Autographacalifornica nuclear polyhedrosis-virus. J Virol, 65(7): 3625–3632.

    PubMed  CAS  Google Scholar 

  74. Krappa R, Roncarati R, Knebelmorsdorf D. 1995. Expression of PE38 and IE2, viral members of the C3HC4 finger family, during baculovirus infection-PE38 and IE2 localize to distinct nuclear regions. J Virol, 69(9): 5287–5293.

    PubMed  CAS  Google Scholar 

  75. Kuzio J, Jaques R, Faulkner P. 1989. Identification of P74, a gene essential for virulence of baculovirus occlusion bodies. Virology, 173(2): 759–763.

    PubMed  CAS  Google Scholar 

  76. LaCount D J, Friesen P D. 1997. Role of early and late replication events in induction of apoptosis by baculoviruses. J Virol, 71(2): 1530–1537.

    PubMed  CAS  Google Scholar 

  77. Lery X, Giannotti J, Taha A, et al. 1997. Multiplication of a granulosis virus isolated from the potato tuber moth in a new established cell line of Phthorimaea operculella. In Vitro Cell Dev Biol-Anim, 33(8): 640–646.

    PubMed  CAS  Google Scholar 

  78. Long G, Westenberg M, Wang H L, et al. 2006. Function, oligomerization and N-linked glycosylation of the Helicoverpa armigera single nucleopolyhedrovirus envelope fusion protein. J Gen Virol, 87 839-846.

  79. Lu A, Miller L K. 1995. Differential requirements for baculovirus late expression factor genes in 2 cell-lines. J Virol, 69(10): 6265–6272.

    PubMed  CAS  Google Scholar 

  80. Lu A, Miller L K. 1995. The roles of 18 baculovirus late expression factor genes in transcription and DNA-replication. J Virol, 69(2): 975–982.

    PubMed  CAS  Google Scholar 

  81. Lu A, Miller L K. 1996. Species-specific effects of the hcf-1 gene on baculovirus virulence. J Virol, 70(8): 5123–5130.

    PubMed  CAS  Google Scholar 

  82. Lung O, Westenberg M, Vlak J M, et al. 2002. Pseudotyping Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV): F proteins from group II NPVs are functionally analogous to AcMNPV GP64. J Virol, 76(11): 5729–5736.

    PubMed  CAS  Google Scholar 

  83. Lynn D E. 2001. Novel techniques to establish new insect cell lines. In Vitro Cell Dev Biol-Anim, 37(6): 319–321.

    PubMed  CAS  Google Scholar 

  84. Lynn D E. 2003. Comparative susceptibilities of insect cell lines to infection by the occlusion-body derived phenotype of baculoviruses. J Invertebr Pathol, 83(3): 215–222.

    PubMed  Google Scholar 

  85. Maeda S, Kamita S G, Kondo A. 1993. Host-range expansion of Autographa-californica nuclear polyhedrosis-virus (NPV) following recombination of a 0.6- Kilobase-pair DNA fragment originating from Bombyx-mori NPV. J Virol, 67(10): 6234–6238.

    PubMed  CAS  Google Scholar 

  86. Martin O, Croizier G. 1997. Infection of a Spodoptera frugiperda cell line with Bombyx mori nucleopoly hedrovirus. Virus Res, 47(2): 179–185.

    PubMed  CAS  Google Scholar 

  87. McClintock J T, Dougherty E M. 1987. Superinfection of baculovirus-infected gypsy-moth cells with the nuclear polyhedrosis viruses of Autographa-californica and Lymantria-dispar. Virus Res, 7(4): 351–364.

    CAS  Google Scholar 

  88. McClintock J T, Dougherty E M, Weiner R M. 1986. Semipermissive replication of a nuclear polyhedrosisvirus of Autographa-californica in a gypsy-moth cell-line. J Virol, 57(1): 197–204.

    PubMed  CAS  Google Scholar 

  89. Miller L K. 1997. The Baculoviruses. New York: Plenum Press

    Google Scholar 

  90. Miller L K, Lu A. 1997. The molecular basis of baculovirus host range, In:The Baculoviruses (Miller L K,ed.), New York: Plenum Press. p217–235.

    Google Scholar 

  91. Mita K, Kasahara M, Sasaki S, et al. 2004. The genome sequence of silkworm, Bombyx mori. Dna Research, 11(1): 27–35.

    PubMed  CAS  Google Scholar 

  92. Morishima N, Okano K, Shibata T, et al. 1998. Homologous p35 proteins of baculoviruses show distinctive anti- apoptotic activities which correlate with the apoptosis- inducing activity of each virus. FEBS Lett, 427(1): 144–148.

    PubMed  CAS  Google Scholar 

  93. Morris T D, Miller L K. 1992. Promoter influence on baculovirus-mediated gene-expression in permissive and nonpermissive insect cell-lines. J Virol, 66(12): 7397–7405.

    PubMed  CAS  Google Scholar 

  94. Morris T D, Miller L K. 1993. Characterization of productive and nonproductive AcMNPV infection in selected insect-cell lines. Virology, 197(1): 339–348.

    PubMed  CAS  Google Scholar 

  95. Morris T D, Todd J W, Fisher B, et al. 1994. Identification of Lef-7 — a baculovirus gene affecting late gene-expression. Virology, 200(2): 360–369.

    PubMed  CAS  Google Scholar 

  96. Morse M A, Marriott A C, Nuttall P A. 1992. The glycoprotein of Thogoto virus (a tick-borne Orthomyxo-like virus) is related to the baculovirus glycoprotein gp64. Virology, 186(2): 640–646.

    PubMed  CAS  Google Scholar 

  97. Murges D, Quadt I, Schroer J, et al. 2001. Dynamic nuclear localization of the baculovirus proteins IE2 and PE38 during the infection cycle: The promyelocytic leukemia protein colocalizes with IE2. Exp Cell Res, 264(2): 219–232.

    PubMed  CAS  Google Scholar 

  98. Naser W L, Miltenburger H G, Harvey J P, et al. 1984. In vitro replication of the Cydia-pomonella (codling moth) granulosis-virus. Fems Microbiol Lett, 24(1): 117–121.

    Google Scholar 

  99. Ohkawa T, Washburn J O, Sitapara R, et al. 2005. Specific binding of Autographa californica M nucleopoly-hedrovirus occlusion-derived virus to midgut cells of Heliothis virescens larvae is mediated by products of pif genes Ac119 and Ac022 but not by Ac115. J Virol, 79(24): 15258–15264.

    PubMed  CAS  Google Scholar 

  100. Passarelli A L, Miller L K. 1993. 3 Baculovirus genes involved in late and very late gene- expression — IE-1, IE-N, and Lef-2. J Virol, 67(4): 2149–2158.

    PubMed  CAS  Google Scholar 

  101. Pearson M N, Groten C, Rohrmann G F. 2000. Identification of the Lymantria dispar nucleopoly-hedrovirus envelope fusion protein provides evidence for a phylogenetic division of the Baculoviridae. J Virol, 74(13): 6126–6131.

    PubMed  CAS  Google Scholar 

  102. Pearson M N, Rohrmann G F. 2002. Transfer, incorporation, and substitution of envelope fusion proteins among members of the Baculoviridae, Orthomyxoviridae, and Metaviridae (insect retrovirus) families. J Virol, 76(11): 5301–5304.

    PubMed  CAS  Google Scholar 

  103. Pijlman G P, Pruijssers A J P, Vlak J M. 2003. Identification of pif-2, a third conserved baculovirus gene required for per os infection of insects. J Gen Virol, 84:2041–2049.

    PubMed  CAS  Google Scholar 

  104. Prikhod’ko E A, Lu A, Wilson J A, et al. 1999. In vivo and in vitro analysis of baculovirus ie-2 mutants. J Virol, 73(3): 2460–2468.

    PubMed  Google Scholar 

  105. Rahman M, Gopinathan K P. 2003. Analysis of host specificity of two closely related baculoviruses in permissive and nonpermissive cell lines. Virus Res, 93(1): 13–23.

    PubMed  CAS  Google Scholar 

  106. Randall R E, Goodbourn S. 2008. Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J Gen Virol, 89:1–47.

    PubMed  CAS  Google Scholar 

  107. Rapp J C, Wilson J A, Miller L K. 1998. Nineteen baculovirus open reading frames, including LEF-12, support late gene expression. J Virol, 72(12): 10197–10206.

    PubMed  CAS  Google Scholar 

  108. Saurin A J, Borden K L B, Boddy M N, et al. 1996. Does this have a familiar RING? Trends Biochem Sci, 21(6): 208–214.

    PubMed  CAS  Google Scholar 

  109. Song J J, Wang R R, Deng F, et al. 2008. Functional studies of per os infectivity factors of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus. J Gen Virol, 89: 2331–2338.

    PubMed  CAS  Google Scholar 

  110. Thiem S M. 1997. Prospects for altering host range for baculovirus bioinsecticides. Curr Opin Biotechnol, 8(3): 317–322.

    PubMed  CAS  Google Scholar 

  111. Thiem S M, Chejanovsky N. 2004. The role of baculovirus apoptotic suppressors in AcMNPV-mediated translation arrest in Ld652Y cells. Virology, 319(2): 292–305.

    PubMed  CAS  Google Scholar 

  112. Thiem S M, Du X L, Quentin M E, et al. 1996. Identification of a Baculovirus gene that promotes Autographa californica nuclear polyhedrosis virus replication in a nonpermissive insect cell line. J Virol, 70(4): 2221–2229.

    PubMed  CAS  Google Scholar 

  113. Todd J W, Passarelli A L, Lu A, et al. 1996. Factors regulating baculovirus late and very late gene expression in transient-expression assays. J Virol, 70(4): 2307–2317.

    PubMed  CAS  Google Scholar 

  114. Vail P V, Hoffmann D F, Streett D A, et al. 1993. Infectivity of a Nuclear Polyhedrosis-Virus isolated from Anagrapha-falcifera (Lepidoptera, Noctuidae) against production and postharvest pests and homologous cell-lines. Environ Entomol, 22(5): 1140–1145.

    Google Scholar 

  115. van Oers M M, Vlak J M. 2007. Baculovirus genomics. Curr Drug Targets, 8:1051–1068.

    PubMed  Google Scholar 

  116. Vaughn J L, Goodwin R H, Tompkins G J, et al. 1977. Establishment of 2 cell lines from insect Spodoptera-frugiperda (Lepidoptera-Noctuidae). In: Vitro-Journal of the Tissue Culture Association, 13(4): 213–217.

    CAS  Google Scholar 

  117. Volkman L E, Goldsmith P A. 1984. Budded Autographa-californica NPV-64k protein-Further biochemicalanalysis and effects of postimmunoprecipitation sample preparation conditions. Virology, 139(2): 295–302.

    PubMed  CAS  Google Scholar 

  118. Volkman L E, Goldsmith P A. 1985. Mechanism of neutralization of budded Autographa-californica Nuclear Polyhedrosis-Virus by a Monoclonal-antibody-Inhibition of entry by adsorptive endocytosis. Virology, 143(1): 185–195.

    PubMed  CAS  Google Scholar 

  119. Volkman L E, Goldsmith P A, Hess R T. 1986. Alternate pathway of entry of budded Autographa-californica Nuclear Polyhedrosis-Virus-Fusion at the plasma-membrane. Virology, 148(2): 288–297.

    PubMed  CAS  Google Scholar 

  120. Volkman L E, Goldsmith P A, Hess R T, et al. 1984. Neutralization of budded Autographa-californica NPV by a monoclonal-antibody-Identification of the target antigen. Virology, 133(2): 354–362.

    PubMed  CAS  Google Scholar 

  121. Volkman L E, Knudson D L. 1986. In vitro replication of baculoviruses, In: The biology of baculoviruses (Granados R R, Federici B A,ed.), Boca Raton: CRC Press. vol 1: p109–127.

    Google Scholar 

  122. Volkman L E, Summers M D, Hsieh C H. 1976. Occluded and nonoccluded Nuclear Polyhedrosis-Virus grown in Trichoplusia-ni — Comparative neutralization, comparative infectivity, and Invitro growth studies. J Virol, 19(3): 820–832.

    PubMed  CAS  Google Scholar 

  123. Wang L, Salem T Z, Lynn D E, et al. 2008. Slow cell infection, inefficient primary infection and inability to replicate in the fat body determine the host range of Thysanoplusia orichalcea nucleopolyhedrovirus. J Gen Virol, 89: 1402–1410.

    PubMed  CAS  Google Scholar 

  124. Washburn J O, Chan E Y, Volkman L E, et al. 2003. Early synthesis of budded virus envelope fusion protein GP64 enhances Autographa californica multicapsid nucleopolyhedrovirus virulence in orally infected Heliothis virescens. J Virol, 77(1): 280–290.

    PubMed  CAS  Google Scholar 

  125. Washburn J O, Haas-Stapleton E J, Tan F F, et al. 2000. Co-infection of Manduca sexta larvae with polydnavirus from Cotesia congregata increases susceptibility to fatal infection by Autographa californica M Nucleopolyhedrovirus. J Insect Physiol, 46(2): 179–190.

    PubMed  CAS  Google Scholar 

  126. Washburn J O, Kirkpatrick B A, Volkman L E. 1995. Comparative pathogenesis of Autographa-californica M Nuclear Polyhedrosis-Virus in larvae of Trichoplusia-ni and Heliothis-virescens. Virology, 209(2): 561–568.

    PubMed  CAS  Google Scholar 

  127. Washburn J O, Kirkpatrick B A, Volkman L E. 1996. Insect protection against viruses. Nature, 383(6603): 767–767.

    CAS  Google Scholar 

  128. Washburn J O, Trudeau D, Wong J F, et al. 2003. Early pathogenesis of Autographa californica multiple nucleopolyhedrovirus and Helicoverpa zea single nucleo-polyhedro virus in Heliothis virescens: a comparison of the “M” and “S” strategies for establishing fatal infection. J Gen Virol, 84: 343–351.

    PubMed  CAS  Google Scholar 

  129. Waterhouse R M, Kriventseva E V, Meister S, et al. 2007. Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. Science, 316: 1738–1743.

    PubMed  CAS  Google Scholar 

  130. Westenberg M, Uijtdewilligent P, Vlak J M. 2007. Baculovirus envelope fusion proteins F and GP64 exploit distinct receptors to gain entry into cultured insect cells. J Gen Virol, 88: 3302–3306.

    PubMed  CAS  Google Scholar 

  131. Wickham T J, Shuler M L, Hammer D A, et al. 1992. Equilibrium and kinetic-analysis of Autographa-californica Nuclear Polyhedrosis-Virus attachment to different insect cell- lines. J Gen Virol, 73: 3185–3194.

    PubMed  CAS  Google Scholar 

  132. Wilson J A, Forney S D, Ricci A M, et al. 2005. Expression and mutational analysis of Autographa californica nucleopolyhedrovirus HCF-1: Functional requirements for cysteine residues. J Virol, 79(22): 13900–13914.

    PubMed  CAS  Google Scholar 

  133. Winstanley D, Crook N E. 1993. Replication of Cydiapomonella Granulosis-Virus in cell-cultures. J Gen Virol, 74: 1599–1609.

    PubMed  Google Scholar 

  134. Wu W W, Wang J W, Xie F, et al. 2003. Baculovirus p74 gene is a species-specific gene. Acta Biochim Biophys Sin, 35(9): 834–840.

    PubMed  CAS  Google Scholar 

  135. Wu Y T, Carstens E B. 1998. A baculovirus single-stranded DNA binding protein, LEF-3, mediates the nuclear localization of the putative helicase P143. Virology, 247(1): 32–40.

    PubMed  CAS  Google Scholar 

  136. Xi Z, Ramirez J L, Dimopoulos G. 2008. The Aedes aegypti Toll Pathway Controls Dengue Virus Infection. PLoS Pathogens, 4(7): e1000098.

    PubMed  Google Scholar 

  137. Zanotto P M D, Kessing B D, Maruniak J E. 1993. Phylogenetic interrelationships among Baculoviruses — Evolutionary rates and host associations. J Invertebr Pathol, 62(2): 147–164.

    PubMed  CAS  Google Scholar 

  138. Zhang J H, Washburn J O, Jarvis D L, et al. 2004. Autographa californica M nucleopolyhedrovirus early GP64 synthesis mitigates developmental resistance in orally infected noctuid hosts. J Gen Virol, 85: 833–842.

    PubMed  CAS  Google Scholar 

  139. Zoog S J, Schiller J J, Wetter J A, et al. 2002. Baculovirus apoptotic suppressor P49 is a substrate inhibitor of initiator caspases resistant to P35 in vivo. Embo J, 21(19): 5130–5140.

    PubMed  CAS  Google Scholar 

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  1. Suzanne M. Thiem

    Present address: Dept. of Entomology, 243 Natural Science, Michigan State University, East Lansing, MI, 48824, USA

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  1. Department of Entomology, and Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, 48824, USA

    Suzanne M. Thiem

  2. Department of Microbiology, Miami University, Oxford, OH, 45056, USA

    Xiao-Wen Cheng

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Thiem, S.M., Cheng, XW. Baculovirus host-range. Virol. Sin. 24, 436–457 (2009). https://doi.org/10.1007/s12250-009-3058-8

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