Abstract
18F-Fluorocholine (FCH) PET/CT is evolving as a functional imaging modality for the preoperative imaging of abnormal parathyroid tissue(s) helping to localize eutopic and ectopic parathyroid tissue and limit the extent of surgery. FCH PET/CT may show incidental uptake in various thyroid lesions necessitating further evaluation, whereas the role of 18F-fluorodeoxyglucose (FDG) PET/CT in the detection of incidental thyroid nodules is well documented. The case of a middle-aged woman with dual pathology of parathyroid adenoma and papillary thyroid cancer detected on FCH and FDG PET/CT is presented.
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21 September 2017
An erratum to this article has been published.
References
Lezaic L, Rep S, Sever MJ, Kocjan T, Hocevar M, Fettich J. 18F-Fluorocholine PET/CT for localization of hyperfunctioning parathyroid tissue in primary hyperparathyroidism: a pilot study. Eur J Nucl Med Mol Imaging. 2014;41:2083–9.
Eccles A, Challapalli A, Khan S, Barwick T, Mangar S. Thyroid lymphoma incidentally detected by 18F-fluorocholine (FCH) PET/CT. Clin Nucl Med. 2013;38:755–7.
Aziz AL, Courbon F, Dierickx LO, Pascal P, Zerdoud S. Oncocytic adenoma of thyroid incidentally detected by 18F-fluorocholine PET/CT. J Nucl Med Technol. 2015;43:133–4.
Wu HB, Wang QS, Wang MF, Li HS. Utility of 11C-choline imaging as a supplement to F-18 FDG PET imaging for detection of thyroid carcinoma. Clin Nucl Med. 2011;36:91–5.
Paone G, Treglia G, Bongiovanni M, Ruberto T, Ceriani L, Giovanella L. Incidental detection of Hürthle cell adenoma by 18F-choline PET/CT scan in a patient with prostate cancer. Rev Esp Med Nucl Imagen Mol. 2013;32:340–1.
Piccardo A, Massollo M, Bandelloni R, Arlandini A, Foppiani L. Lymph node metastasis from tall-cell thyroid cancer negative on 18F-FDG PET/CT and detected by 18F-choline PET/CT. Clin Nucl Med. 2015;40:e417–9.
Soelberg KK, Bonnema SJ, Brix TH, Hegedüs L. Risk of malignancy in thyroid incidentalomas detected by 18F-fluorodeoxyglucose positron emission tomography; a systematic review. Thyroid. 2012;22:918–25.
Hindie E, Ugur O, Fuster D, O’Doherty M, Grassetto G, Urena P, et al. 2009 EANM parathyroid guidelines. Eur J Nucl Med Mol Imaging. 2009;36:1201–16.
Vriens D, de Wilt JH, van der Wilt GJ, Netea-Maier RT, Oyen WJ, de Geus-Oei LF. The role of [18F]-2-fluoro-2-deoxy-d-glucose-positron emission tomography in thyroid nodules with indeterminate fine-needle aspiration biopsy: systematic review and meta-analysis of the literature. Cancer. 2011;117:4582–94.
Savelli G, Basile P, Muni A, Bna C, Pizzocaro C, Pagani R. Focal thyroid uptake during 18F-choline PET/CT: a case report. Case Rep Clin Med. 2015;4:345–8.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the principles of the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.
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The institutional review board of our institution approved this retrospective study, and the requirement to obtain informed consent was waived.
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The original version of this article was revised to correct the name of the fifth author.
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Thanseer, N.T.K., Bhadada, S.K., Sood, A. et al. Dual Pathologies of Parathyroid Adenoma and Papillary Thyroid Cancer on Fluorocholine and Fluorodeoxyglucose PET/CT. Nucl Med Mol Imaging 52, 154–158 (2018). https://doi.org/10.1007/s13139-017-0488-3
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DOI: https://doi.org/10.1007/s13139-017-0488-3