Abstract
Olax psittacorum (Lam.) Vahl. traditionally used by the tribal community of ‘INDIA’ to heal conditions such as pain, psoriasis, mouth-ulcer, anemia, constipation as well as diabetes. Documented scientific shreds of evidence like antipyretic, anti-inflammatory, antimicrobial, anti-viral, anti-cancer, toxicity profile improved its medicinal value. Chromatographic evaluation (GC–MS) proven near about presence of 25 compounds. Among them, hexadecanoic methyl ester, β-sitosterol, phytol, methyl salicylate, 13-docosenamide, and oleanolic acid are significant and contribute to its successful medicinal properties. The toxicity study also revealed the safety of the consumption of the leaf part. Still, consecutive gaps need to be exploring to gather evidence of its contribution to curing different ailments, especially upon the ulcer, anemia, and identification of the presence of lead compounds as an upcoming future research proposal. The ‘Internet Scholar’, ‘Study Guide’, ‘PubMed’, ‘ScienceDirect’, ‘Scopus’, and ‘Sodhganga’ web site have been accessed to gather information about detailed scientific research as well as traditional information from authenticated sources that have been published in the English language. The various folklore claimed medicinal properties like anti-ulcer, aphthous ulcer, analgesic, anti-diabetic, anti-anemic, etc. yet to be justified scientifically with lead compounds that can support the rationality being used as folklore. This plant could be a good choice to explore its importance within the pharmacognostic field of drug development and might be a better source of herbal derived lead compounds which can help to heal ulcer or anemia that can effectively make a credible addition to treatment among the civilization as a natural source of therapeutic compounds.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abubakar AR, Haque M (2020) Preparation of medicinal plants: basic extraction and fractionation procedures for experimental purposes. J Pharm Bioallied Sci 12:1–10. https://doi.org/10.4103/jpbs.JPBS
Chan K, Shaw D, Simmonds MSJ, Leon CJ, Xu Q et al (2012) Good practice in reviewing and publishing studies on herbal medicine, with special emphasis on traditional Chinese medicine and Chinese materia medica. J Ethnopharmacol 140(3):469–475. https://doi.org/10.1016/j.jep.2012.01.038
Chaudhari VK, Pathak D, Hussain Z, Kumar P, Yadav V (2018) Importance of herbal drug for new drug development. J Appl Pharm Sci Res 1(4):19–22. https://doi.org/10.31069/japsr.v1i4.3
Dahanukar SA, Kulkarni RA, Rege NN (2000) Pharmacology of medicinal plants and natural products. Indian J Pharmacol 32(4):S81–S118
Dr. Duke’s LNA (2020) Dr. Duke’s phytochemical and ethnobotanical databases Olax scandens (Olacaceae). https://phytochem.nal.usda.gov/phytochem/ethnoPlants/show/7178?et=. Accessed on 7 April 2020
Duraipandiyan V, Ayyanar M, Ignacimuthu S (2006) Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India. BMC Complement Altern Med. https://doi.org/10.1186/1472-6882-6-35
Forgacs P, Provost J (1981) Olaxoside, a saponin from Olax andronensis, Olax glabriflora and Olax puttacorum. Phytochemistry 20(7):1689–1691. https://doi.org/10.1016/S0031-9422(00)98556-X
Fortin H, Vigor C, Lohézic-Le Dévéhat F, Robin V, Le Bossé B et al (2002) In vitro antiviral activity of thirty-six plants from La Réunion Island. Fitoterapia 73:346–350. https://doi.org/10.1016/S0367-326X(02)00080-1
Galm U, Shen B (2007) Natural product drug discovery: the times have never been better. Chem Biol 14(10):1098–1104. https://doi.org/10.1016/j.chembiol.2007.10.004
Group Efloraofindia (2007) Olax scandens Roxb. https://sites.google.com/site/efloraofindia/species/m—z/o/olacaceae/olax/olax-scandens. Accessed on 22 April 2020
Groupmembers Efloraofindia (2007) Database of Indian plants—developed by the members of Efloraofindia Google group. Google. https://sites.google.com/site/efloraofindia/species/m—z/o/olacaceae/olax/olax-scandens. Accessed on 1 June 2020
Haron NW, Ping ST (1997) Distribution and taxonomic significance of flavonoids in the olacaceae and icacinaceae. Biochem Syst Ecol 25(3):263–265. https://doi.org/10.1016/S0305-1978(96)00105-6
Huang H (2011) Plant diversity and conservation in China: planning a strategic bioresource for a sustainable future. Bot J Linn Soc 166(3):282–300. https://doi.org/10.1111/j.1095-8339.2011.01157.x
Jamshidi-Kia F, Lorigooini Z, Amini-Khoei H (2018) Medicinal plants: past history and future perspective. J HerbMed Pharmacol 7(1):1–7. https://doi.org/10.15171/jhp.2018.01
Jeyaprakash K, Ayyanar M, Geetha KN, Sekar T (2011) Traditional uses of medicinal plants among the tribal people in Theni District (Western Ghats), Southern India. Asian Pac J Trop Biomed 1(1):S20–S25. https://doi.org/10.1016/s2221-1691(11)60115-9
Khare CP (2007) Indian medicinal plants an illustrated dictionary. In: Khare CP (ed) Indian medicinal plants, vol 447. Springer, New Delhi. https://doi.org/10.1007/978-0-387-70638-2
Kumbhare MR, Guleha V, Sivakumar T (2012) Estimation of total phenolic content, cytotoxicity and in vitro antioxidant activity of stem bark of Moringa oleifera. Asian Pacific J Trop Dis 2(2):144–150. https://doi.org/10.1016/s2222-1808(12)60033-4
Mahapatra AK, Panda PC (2009) Wild edible fruit plants of eastern India. First. In: Mahapatra AK, Panda PC (eds). Published by Regional Plant Resource Centre Nayapalli, Bhubaneswar
Majumder R, Adhikari L, Dhara M (2015) Comparative study of leaves and stem methanolic extract on antioxidant and antimicrobial activity through quantitative evaluation of phytoconstituents. Int J Eng Technol Manag Appl Sci 3(September):208–216
Majumder R, Dhara M, Adhikari L, Ghosh G, Pattnaik S (2019a) Evaluation of in vitro antibacterial and antioxidant activity of aqueous extracts of Olax psittacorum. Indian J Pharm Sci 81(1):99–109. https://doi.org/10.4172/pharmaceutical-sciences.1000484
Majumder R, Adhikari L, Hossain CM, Dhara M, Sahu J (2019b) Toxicological evaluation, brine shrimp lethality assay, in vivo and ex vivo antioxidant assessment followed by GC–MS study of the extracts obtained from Olax psittacorum (Lam.) Vahl. Orient Pharm Exp Med. https://doi.org/10.1007/s13596-019-00384-y
Mujeeb AA, Khan NA, Jamal F, Badre Alam KF, Saeed H et al (2020) Olax scandens mediated biogenic synthesis of Ag–Cu nanocomposites: potential against inhibition of drug-resistant microbes. Front Chem 8(February):1–12. https://doi.org/10.3389/fchem.2020.00103
Mukherjee S, Chowdhury D, Kotcherlakota R, Patra S, Vinothkumar B et al (2014) Potential theranostics application of bio-synthesized silver nanoparticles (4-in-1 system). Theranostics 4(3):316–335. https://doi.org/10.7150/thno.7819
Nahak G, Suar M, Sahu RK (2014) Antioxidant potential and nutritional values of vegetables: a review. Res J Med Plant 8(2):50–81
Naik R, Borkar S, Harisha CR, Acharya RN (2013) A detailed pharmacognostical evaluation on leaf of Olax scandens Roxb. Glob J Res Med Plants Indig Med 2(11):745–751
Naik R, Acharya R, Nariya MB, Borkar SD (2015a) Evaluation of acute toxicity and intestinal transit time of Olax scandens Roxb. leaves. J Res Ayurveda 36:437–439. https://doi.org/10.4103/0974-8520.190689
Naik R, Borkar SD, Acharya R, Nariya MB (2015b) Evaluation of antipyretic activity of Olax scandens (Roxb.) stem bark. Res Rev J Pharmacol 5(1):15–18
Naik R, Borkar SD, Acharya RN, Shukla V (2015c) Evaluation of phytochemical content, nutritional value and antioxidant activity of Olax scandens (Roxb) leaves. Int Ayurvedic Med J 3(3):702–709
Olowa LF, Nuneza OM (2013) Brine shrimp lethality assay of the ethanolic extracts of three selected species of medicinal plants from Iligan City, Philippines. Int Res J Biol Sci 2(11):74–77
Pal SK, Shukla Y (2003) Herbal medicine: current status and the future. Asian Pac J Cancer Prev 4(4):281–288
Panda T, Padhy R (2007) Sustainable food habits of the hill-dwelling Kandha tribe in Kalahandi district of Orissa. Indian J Tradit Knowl 06(1):103–105
Parry O, Okwuasaba FK, Ekpenyong KI, Ashraf CM (1986) Effects of Olax gambecola methanol extract on smooth muscle and rat blood pressure. J Ethnopharmacol 18:63–88
Patale CK, Nasare PN, Narkhede SD (2015) Ethnobotanical studies on wild edible plants of Gond, Halba, Kawar tribes of Salekasa Taluka, Gondia District, Maharashtra State, India. Int Res J Pharma 6(8):512–518. https://doi.org/10.7897/2230-8407.068103
Phillipson JD (2001) Phytochemistry and medicinal plants. Phytochemistry 56(3):237–243. https://doi.org/10.1016/S0031-9422(00)00456-8
Rasool Hassan BA (2012) Medicinal plants (importance and uses). Pharm Anal Acta 03(10):4172. https://doi.org/10.4172/2153-2435.1000e139
Reddy RV (1995) Ethnobotanical and phytochemical studies on medicinal plant resources of Cuddapah district A P India. Sri Krishnadevaraya University, Anantapur
Roskov Y, Abucay L, Orrell T, Nicolson D, Kunze T et al (2015) Plant scientific classification web page. Digital Resources. www.catalogueoflife.org/col. Accessed 22 Apr 2020
Sahu R, Kar M, Routray R (2013) DPPH free radical scavenging activity of some leafy vegetables used by tribals of Odisha, India. J Med Plants Stud 1(4):21–27
Santhosh Kumar JU, Krishna Chaitanya MJ, Andrew J (2019) Indigenous knowledge of medicinal plants used by ethnic communities of South India. Ethnobot Res Appl. https://doi.org/10.32859/era.18.4.1-112
Sinha R, Lakra V (2005) Wild tribal food plants of Orissa. Indian J Tradit Knowl 04(3):246–252
Sivaprabha J (2014) Anticancer and apoptosis inducing effect of methanolic extract of leaves and rhizomes of Curcuma amada Roxb in breast cancer cell lines by. Avinashilingam Deemed University for Women, Coimbatore
Sreeramulu N, Suthari S, Ragan A, Raju VS (2013) Ethno-botanico-medicine for common human ailments in Nalgonda and Warangal districts of Telangana, Andhra Pradesh, India. Ann Plant Sci 2(7):220–229
Tan N, Zhou J, Zhao S (1999) Advances in structural elucidation of glucuronide oleanane-type triterpene carboxylic acid 3,28-O-bisdesmosides (1962–1997). Phytochemistry 52(2):153–192. https://doi.org/10.1016/S0031-9422(98)00454-3
Tilburt JC, Kaptchuk TJ (2008) Herbal medicine research and global health: an ethical analysis. Bull World Health Organ 86(8):594–599. https://doi.org/10.2471/BLT.07.042820
Venkata Subbaiah KP, Savithramma N (2012) Bio-prospecting and documentation of traditional medicinal plants used to treat itching, psoriasis and wounds by ethnic groups of Kurnool District, Andhra Pradesh, India. Asian J Pharm Clin Res 5(2):127–131
Verma S, Singh SP (2008) Current and future status of herbal medicines. Vet World 1(11):347–350. https://doi.org/10.5455/vetworld.2008.347-350
Wiart C (2006) (ed) Family Caricaceae. In: Medicinal plants of the Asia–Pacific: drugs for the future?. World Scientific Publishing Co. Pte. Ltd, Singapore
Acknowledgements
Our heartfelt thanks go to the Pharmacognosy Department of School of Pharmaceutical Sciences (SPS), SOA Deemed to be University, for leading us through the phase of data collection via the internet. We also remember and thankful to Mr. Durga, Pharmaceutical Department, Laboratory Assistant at SPS, SOA University, as his native place in ‘Andharuya’ to interact with the local elderly people to collect data on the medical or traditional use of this plant. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Ethical statement
This article does not contain any studies with human participants or animals performed by any of the authors.
Conflict of interest
Raja Majumder has no conflict of interest. Lopamudra Adhikari has no conflict of interest. Moonmun Dhara has no conflict of interest.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Majumder, R., Adhikari, L. & Dhara, M. Olax psittacorum (Lam.) Vahl. (Olacaceae): current status and future prospects as an herbal plant. ADV TRADIT MED (ADTM) 22, 251–258 (2022). https://doi.org/10.1007/s13596-020-00493-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13596-020-00493-z