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Slow release formulation of herbicide metazachlor based on high molecular weight poly(lactic acid) submicro and microparticles

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Abstract

Frequently used pre-emergent herbicide metazachlor was encapsulated into high molecular weight poly(lactic acid) particles, and its subsequent release and the effectivity of such formulations were investigated. Two sets of polymeric micro- and submicro particles, both with the theoretical metazachlor loading of 20%, 30%, and 40%, were prepared and characterized. Loading efficiency reached 80% for both types of particles. Release profiles were tested in vitro for the individual particle variants and were shown to have a bimodal profile with the initial fast burst release and much slower second phase. Finally, selected formulations were tested in vivo against target plants (field poppy and barnyard grass) and non-targets plants (mustard and rapeseed) and showed improved inhibition of target plants (about 30% higher for barnyard grass) and at the same time lower inhibition of non-target plants (rapeseed) in comparison with the identical dose of metazachlor alone.

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Acknowledgements

Financial support from Tomas Bata University in Zlín, Internal Grant Agencies (Project IGA/FT/2018/009 and IGA/FT/2019/011) was gratefully acknowledged.

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Authors and Affiliations

  1. Department of Environmental Protection Engineering, Faculty of Technology, Tomas Bata University, Vavrečkova 275, 760 01, Zlín, Czech Republic

    J. Salač, P. Stloukal, N. Janásová & M. Koutný

  2. Department of Food Technology, Faculty of Technology, Tomas Bata University, nám. T.G. Masaryka 5555, 760 01, Zlín, Czech Republic

    T. Šopík

  3. Department of Agroecology and Biometeorology, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, Prague, Czech Republic

    M. Jursík

Authors
  1. J. Salač
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  2. T. Šopík
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  3. P. Stloukal
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  4. N. Janásová
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  5. M. Jursík
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  6. M. Koutný
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Corresponding author

Correspondence to M. Koutný.

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Editorial responsibility: M. Abbaspour.

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Salač, J., Šopík, T., Stloukal, P. et al. Slow release formulation of herbicide metazachlor based on high molecular weight poly(lactic acid) submicro and microparticles. Int. J. Environ. Sci. Technol. 16, 6135–6144 (2019). https://doi.org/10.1007/s13762-019-02222-9

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  • DOI: https://doi.org/10.1007/s13762-019-02222-9

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