Abstract
Purpose
Congenital anomalies, also known as birth defects have been the primary focus of a number of studies globally. Our primary objective is to evaluate the significance of MRI in the prenatal diagnosis of congenital central nervous system (CNS) anomalies and explore the role of autopsy techniques in the postnatal phase as a verification tool. Additionally, we are focused on proving the MRI-specific diagnostic capabilities in comparison to the current gold standard based on autopsy.
Methods
The study is based on a thorough analysis of incidences of congenital CNS anomalies in four women and their foetuses. Primary in-vivo MRI diagnostics and subsequent verification via autopsy (postmortem) have been performed.
Results
We described the foetal CNS anomalies based on MRI diagnostics and additionally verified the results by autopsy to confirm the findings and improve the services offered to patients and their families.
Conclusion
The findings of the study confirmed the role of the MRI as a reliable tool for unequivocal diagnosis of congenital CNS anomalies and malformations.
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Data Availability
Data related to this study is available upon request.
References
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The research was supported by an internal project of the Medical University of Plovdiv, Bulgaria.
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Kingsley-Godwin, M.J., Tenev, A., Uchikova, E. et al. Evaluation of the Significance of MRI in the Prenatal Diagnosis of Neural Tube Defects. J. Med. Biol. Eng. 41, 881–887 (2021). https://doi.org/10.1007/s40846-021-00657-5
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DOI: https://doi.org/10.1007/s40846-021-00657-5