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Hypocholesterolemic effect of germinated fenugreek seeds in human subjects

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Abstract

The effect of consumption of germinated fenugreek seed powder at two different levels, i.e., 12.5 g and 18.0 g on the blood lipid profiles of twenty hypocholesterolemic adults of both sexes in the age range of 50–65 years was studied. The subjects were divided into two groups, i.e., Group I and Group II who were asked to incorporate the powder into any dish of their choice at the rates of one packet per day containing 12.5 g and 18.0 g of the germinated powder, respectively, for a period of one month. Fasting blood was drawn intravenously one day before and at the end of 30 days feeding trials. The findings revealed that germination had brought distinct changes in soluble fiber content of the seeds. Consumption of the seed at both the levels resulted in a hypocholesterolemic effect. Between the two levels, higher levels of consumption, i.e., 18.0 g of the germinated seed resulted in a significant reduction in total cholesterol and LDL levels. No significant changes were found in HDL, VLDL and triglyceride levels in all the subjects.

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References

  1. Sharma RD (1987) Role of fenugreek seeds in Diabetes mellitus. Indian Council for Medical Research Bulletin 17(9): 79-83.

    Google Scholar 

  2. Udayasekhara Rao P, Sesikeran B, Srinivasa Rao P, Nadamnui A, Vikas Rao V, Ramachandra RP (1996) Short term Nutritional and safety evaluation of Fenugreek. Nutr Res 16(9): 1495-1505.

    Google Scholar 

  3. Suresh Babu P, Srinivasan K (1993) Influence of dietary spices on adrenal steroidogenesis in rats. Nutr Res 13: 435-444.

    Google Scholar 

  4. Evans AJ, Hood RL, Oakenfull DG, Sidhu GS (1992) Relationship between structure and function of dietary fibre: A comparative study of the effects of three galactomannans on cholesterol metabolism in the rat. Br J Nutr 68: 217-229.

    Google Scholar 

  5. Madar Z, Abdel R, Samish S, Arad J (1988) Glucose-lowering effect of fenugreek in non-insulin dependent diabetics. J Clin Nutr 42: 51-54.

    Google Scholar 

  6. Praveen KB, Dasgupta DJ, Prashar BS, Kaushal SS (1987) Preliminary Report: Effective reduction of LDL cholesterol by indigenous plant products. Current Science 56(12): 80-81.

    Google Scholar 

  7. Sharma RD (1986) Effect of fenugreek seeds and leaves on blood glucose and serum insulin responses in human subjects. Nutr Res 6: 1353-1364.

    Google Scholar 

  8. Sharma RD, Raghuram TC (1990) Hypoglycemic effect of fenugreek seeds in non-insulin dependent diabetic subjects. Nutr Res 10: 731-739.

    Google Scholar 

  9. Sharma RD, Raghuram TC, Sudhakar Rao N (1990) Effect of fenugreek seeds on blood glucose and serum lipids in Type I diabetes. Eur J Clin Nutr 44: 301-306.

    Google Scholar 

  10. Saibaba A, Raghuram TC (1997) Fenugreek - The wonder Seed. Nutrition 31(2): 21-25.

    Google Scholar 

  11. Neeraja A, Rajyalakshmi P (1996) Hypoglycemic effect of processed fenugreek seeds in humans. J Food Sci Technol 33(5): 427-430.

    Google Scholar 

  12. Asp NG, Johansson CG, Hallmer H, Siljestrom M (1983) Rapid Enzymatic assay of insoluble and soluble dietary fibre. J Agri Food Chem 31: 476-482.

    Google Scholar 

  13. Nageshwar Rao G (1983) Statistics for agricultural sciences. Oxford and IBH Publishing company, New Delhi, pp 113-117.

    Google Scholar 

  14. Sharma RD (1984) Hypocholesterolemic activity of fenugreek (Trigonella foenum graecum): An experimental study in rats. Nutr Rep Int 30(1): 221-231.

    Google Scholar 

  15. Ganesh Bhat B, Sambaiah K, Chandrasekhara N (1985) The effect of feeding fenugreek and ginger on bile consumption in the albino rat. Nutr Rep Int 32(5): 1145-1151.

    Google Scholar 

  16. Eastwood MA, Kay MR (1979) An hypothesis for the action of dietary fibre along the gastrointestinal tract. Am J Clin Nutr 32: 364-367.

    Google Scholar 

  17. Anderson JW, Chen WL (1979) Plant fibre: Carbohydrate and lipid metabolism. Am J Clin Nutr 32: 346-363.

    Google Scholar 

  18. Oakenfull D, Sidhu GS (1990) Could saponins be a useful treatment for hypercholesterolemia? Eur J Clin Nutr 44: 79-88.

    Google Scholar 

  19. Sauvaire Y, Ribes G, Baccon JC, Loubatieres MMM (1991) Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek. Lipids 26(3): 191-197.

    Google Scholar 

  20. Shutler MS, Walker AF, Low AG (1987) The cholesterol lowering effects of legumes, I: Effects of the major nutrients. Hum Nutr: Food Sci Nutr 41 F: 71-86.

    Google Scholar 

  21. Sebaiy L, Mahdy RA (1983) Lipid changes during germination of fenugreek seeds (Trigonella foenum graecum). Food Chem 10: 309-319.

    Google Scholar 

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Sowmya, P., Rajyalakshmi, P. Hypocholesterolemic effect of germinated fenugreek seeds in human subjects. Plant Foods Hum Nutr 53, 359–365 (1999). https://doi.org/10.1023/A:1008021618733

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  • DOI: https://doi.org/10.1023/A:1008021618733

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