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Antioxidant Activity of 2-Aminothiazoles Containing a Diterpene Fragment in the Model System of the Liquid-Phase Radical-Chain Oxidation of 1,4-Dioxane

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Abstract

The antioxidant activity of 2-aminothiazoles containing a diterpene fragment in a model system of initiated radical-chain oxidation of 1,4-dioxane was evaluated. The compounds exhibited different inhibitory activities depending on their structure. The effective rate constant of the interaction of substituted 2-aminothiazoles with the 1,4-dioxane peroxyl radical was measured. 2-Aminothiazoles obtained by the chemical transformations of maleopimaric acid N-phenylamide showed higher reactivity with the peroxyl radical.

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Funding

This study was performed under the R&D plan at the Ufa Institute of Chemistry, Russian Academy of Sciences (state registration nos. АААА-А17-117011910034-8 and АААА-А17-117011910025-6), on the equipment of the Chemistry Multiaccess Center.

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Authors and Affiliations

  1. Ufa Institute of Chemistry, Ufa Scientific Center, Russian Academy of Sciences, 450054, Ufa, Bashkortostan, Russia

    L. R. Yakupova, R. A. Nasibullina, V. A. Shamukaev, R. M. Sultanova & R. L. Safiullin

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  1. L. R. Yakupova
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  2. R. A. Nasibullina
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  3. V. A. Shamukaev
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  4. R. M. Sultanova
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  5. R. L. Safiullin
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Correspondence to L. R. Yakupova.

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Translated by L. Smolina

Abbreviations: MPA, maleopimaric acid; N-Ph-MPA, maleopimaric acid N-phenylimide; RH, 4-dioxane.

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Yakupova, L.R., Nasibullina, R.A., Shamukaev, V.A. et al. Antioxidant Activity of 2-Aminothiazoles Containing a Diterpene Fragment in the Model System of the Liquid-Phase Radical-Chain Oxidation of 1,4-Dioxane. Kinet Catal 61, 232–237 (2020). https://doi.org/10.1134/S0023158420020123

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  • DOI: https://doi.org/10.1134/S0023158420020123

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