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Terahertz response of DNA oligonucleotides on the surface of silicon nanostructures

  • Microcrystalline, Nanocrystalline, Porous, and Composite Semiconductors
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Abstract

The possibility of identifying DNA oligonucleotides deposited onto the region of the edge channels of silicon nanostructures is considered. The role of various THz (terahertz) radiation harmonics of silicon nanostructures in the resonance response of oligonucleotides is analyzed. In particular, this makes it possible to compare single-stranded 100_ and 50_mer DNA oligonucleotides. A technique for the rapid identification of different oligonucleotides by measuring changes in the conductance and transverse potential difference of silicon nanostructures with microcavities, embedded in the edge channels for selecting THz radiation characteristics, is proposed.

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References

  1. R. Higuchi, C. Fockler, G. Dollinger, and R. Watson, Nat. Biotechnol. 11, 1026 (1993).

    Article  Google Scholar 

  2. M. K. Udvardi, T. Czechowski, and W. R. Scheible, Plant Cell 20, 1736 (2008).

    Article  Google Scholar 

  3. H. D. VanGuilder, K. E. Vrana, and W. M. Freeman, BioTechniques 44, 619 (2008).

    Article  Google Scholar 

  4. J. Liu, C. Liu, and W. He, Curr. Org. Chem. 17, 564 (2013).

    Article  Google Scholar 

  5. E. R. Mardis, Ann. Rev. Anal. Chem. 6, 287 (2013).

    Article  Google Scholar 

  6. J. M. Rothberg et al., Nature 475, 348 (2011).

    Article  Google Scholar 

  7. C. Toumazou et al., Nat. Methods 10, 641 (2013).

    Article  Google Scholar 

  8. R. E. Webb, Electron. Eng. 37, 803 (1965).

    Google Scholar 

  9. I. Lundstrom, M. S. Shivaraman, C. S. Svenson, and L. Lundkvist, Appl. Phys. Lett. 26, 55 (1975).

    Article  ADS  Google Scholar 

  10. P. Bergveld, Sens. Actuators B 88, 1 (2003).

    Article  Google Scholar 

  11. C. S. Lee, S. K. Kim, and M. Kim, Sensors 9, 7111 (2009).

    Article  Google Scholar 

  12. C. Plesa, N. van Loo, and C. Dekker, Nanoscale 7, 13605 (2015).

    Article  ADS  Google Scholar 

  13. M. Wanunu, Phys. Life Rev. 9, 125 (2012).

    Article  ADS  Google Scholar 

  14. M. Jain, I. T. Fiddes, K. H. Miga, H. E. Olsen, B. Paten, and M. Akeson, Nat. Methods 12, 351 (2015).

    Article  Google Scholar 

  15. M. Muthukumar, C. Plesa, and C. Dekker, Phys. Today 68 (8), 40 (2015).

    Article  Google Scholar 

  16. N. T. Bagraev A. Bouravleuv, W. Gehlhoff, L. Klyachkin, A. Malyarenko, and S. Rykov, Def. Dif. Forum 194, 673 (2001).

    Article  Google Scholar 

  17. N. T. Bagraev, N. G. Galkin, W. Gehlhoff, L. E. Klyachkin, and A. M. Malyarenko, J. Phys.: Condens. Matter 20, 164202 (2008).

    ADS  Google Scholar 

  18. N. T. Bagraev, A. D. Bouravlev, L. E. Klyachkin, A. M. Malyarenko, V. Gehlhoff, V. K. Ivanov, and I. A. Shelykh, Semiconductors 36, 439 (2002).

    Article  ADS  Google Scholar 

  19. N. T. Bagraev, A. D. Bouravlev, L. E. Klyachkin, A. M. Malyarenko, V. Gehlhoff, Yu. I. Romanov, and S. A. Rykov, Semiconductors 39, 685 (2005).

    Article  ADS  Google Scholar 

  20. N. T. Bagraev, W. Gehlhoff, L. E. Klyachkin, A. A. Kudryavtsev, A. M. Malyarenko, G. A. Oganesyan, D. S. Poloskin, and V. V. Romanov, Physica C 219, 437 (2006).

    Google Scholar 

  21. N. T. Bagraev, V. A. Mashkov, E. Yu. Danilovsky, W. Gehlhoff, D. S. Gets, L. E. Klyachkin, A. A. Kudryavtsev, R. V. Kuzmin, A. M. Malyarenko, and V. V. Romanov, Appl. Magn. Reson. 39, 113 (2010).

    Article  Google Scholar 

  22. N. T. Bagraev, E. Yu. Danilovsky, L. E. Klyachkin, A. M. Malyarenko, and V. A. Mashkov, Semiconductors 46, 75 (2012).

    Article  ADS  Google Scholar 

  23. N. T. Bagraev, L. E. Klyachkin, A. A. Kudryavtsev, A. M. Malyarenko, and V. V. Romanov, in Superconductor, Ed. by A. Luiz (SCIYO, Rijeka, 2010), p.69.

  24. N. T. Bagraev, V. Yu. Grigoryev, L. E. Klyachkin, A. M. Malyarenko, V. A. Mashkov, and V. V. Romanov, Fiz. Tekh. Poluprovodn. 50 (8) (2016, in press).

    Google Scholar 

  25. A. L. Chernev, N. T. Bagraev, L. E. Klyachkin, A. K. Emel’yanov, and M. V. Dubina, Semiconductors 49, 944 (2015).

    Article  ADS  Google Scholar 

  26. N. T. Bagraev, E. Yu. Danilovskii, and D. S. Gets, J. Phys.: Conf. Ser. 486, 012017 (2014).

    ADS  Google Scholar 

  27. G. J. Thomas, Jr., Ann. Rev. Biophys. Biomol. Struct. 28, 1 (1999).

    Article  ADS  Google Scholar 

  28. A. Barhoumi, D. Zhang, F. Tam, and N. G. Halas, J. Am. Chem. Soc. 130, 5523 (2008).

    Article  Google Scholar 

  29. B. M. Fischer, M. Walther, and P. Jepsen, Phys. Med. Biol. 47, 3807 (2002).

    Article  Google Scholar 

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Authors and Affiliations

  1. Peter the Great Saint-Petersburg Polytechnic University, ul. Polytekhnicheskaya 29, St. Petersburg, 195251, Russia

    N. T. Bagraev

  2. Ioffe Physical–Technical Institute, Russian Academy of Sciences, ul. Politekhnicheskaya 26, St. Petersburg, 194021, Russia

    N. T. Bagraev, L. E. Klyachkin & A. M. Malyarenko

  3. Saint Petersburg Academic University—Nanotechnology Research and Education Center, Russian Academy of Sciences, ul. Khlopina 8/3, St. Petersburg, 194021, Russia

    A. L. Chernev, A. K. Emel’yanov & M. V. Dubina

Authors
  1. N. T. Bagraev
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  2. A. L. Chernev
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  3. L. E. Klyachkin
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  4. A. M. Malyarenko
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  5. A. K. Emel’yanov
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  6. M. V. Dubina
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Correspondence to N. T. Bagraev.

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Original Russian Text © N.T. Bagraev, A.L. Chernev, L.E. Klyachkin, A.M. Malyarenko, A.K. Emel’yanov, M.V. Dubina, 2016, published in Fizika i Tekhnika Poluprovodnikov, 2016, Vol. 50, No. 9, pp. 1230–1237.

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Bagraev, N.T., Chernev, A.L., Klyachkin, L.E. et al. Terahertz response of DNA oligonucleotides on the surface of silicon nanostructures. Semiconductors 50, 1208–1215 (2016). https://doi.org/10.1134/S1063782616090037

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  • DOI: https://doi.org/10.1134/S1063782616090037

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