Overview
- Editors:
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Viswanathan Natarajan
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Department of Pharmaology and Medicine, University of Illinois at Chicago, Chicago, USA
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Narasimham L. Parinandi
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Division of Allergy, Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, College of Medicine, Ohio State University Wexner, Medical Center, Columbus, USA
- Comprehensive, state-of-the-art review
- Written by experts in the field
- Covers both research and clinical issues
- Includes supplementary material: sn.pub/extras
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Table of contents (9 chapters)
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- Harijith Anantha, Prasad Kanteti, Panfeng Fu, Sainath R. Kotha, Narasimham L. Parinandi, Viswanathan Natarajan
Pages 1-25
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- Narsa M. Reddy, Wajiha Qureshi, Haranath Potteti, Dhananjaya V. Kalvakolanu, Sekhar P. Reddy
Pages 27-50
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- Ulaganathan Mabalirajan, Anurag Agrawal, Balaram Ghosh
Pages 51-70
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- Ganesh K. Kumar, Gayatri Raghuraman, Nanduri R. Prabhakar
Pages 71-91
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- Niccole Schaible, Philippe Delmotte, Gary C. Sieck
Pages 93-116
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- Sainath R. Kotha, Travis O. Gurney, Miles U. Magalang, Thomas J. Hund, Abhay R. Satoskar, Peter J. Mohler et al.
Pages 117-139
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- Lidza Kalifa, Michael A. O’Reilly
Pages 141-159
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- Luis Puente-Maestu, Jorge Chancafe-Morgan
Pages 161-176
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- Katherine L. Tuggle, Michelle V. Fanucchi
Pages 177-214
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Back Matter
Pages 215-222
About this book
Mitochondria, often referred to as the “powerhouses” of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.
Editors and Affiliations
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Department of Pharmaology and Medicine, University of Illinois at Chicago, Chicago, USA
Viswanathan Natarajan
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Division of Allergy, Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, College of Medicine, Ohio State University Wexner, Medical Center, Columbus, USA
Narasimham L. Parinandi