Overview
- This book will provide an in-depth description of resistance to targeted therapies in breast cancer
- This book will discuss targeted therapies used to treat ER+ or Her2+ breast cancers (i.e. Tamoxifen or trastuzumab)
- This book will also discuss targeting signaling pathways activated in triple negative breast cancer (i.e. EGFR and Wnt signaling)
- This book will give insight into the landscape of breast cancer treatment and the challenges of targeted therapy
- This book will provide a glimpse into the future of breast cancer therapy
Part of the book series: Resistance to Targeted Anti-Cancer Therapeutics (RTACT, volume 16)
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Table of contents (7 chapters)
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Front Matter
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Back Matter
Keywords
About this book
We present an in-depth description of resistance to targeted therapies in breast cancer. Targeted therapies discussed here include those used to treat ER+ or Her2+ breast cancers (i.e., Tamoxifen or trastuzumab) or those targeting signaling pathways aberrantly activated in triple negative breast cancer (i.e., EGFR and Wnt signaling). We have also provided an overview of standard of care as an introduction into the importance of targeted therapy. It is our hope that this volume gives an insight into the landscape of breast cancer treatment, the challenges of targeted therapy, and a glimpse into the future of breast cancer therapy.
Editors and Affiliations
About the editor
Dr. Prosperi received her BA in Microbiology from Miami University (OH), and went on to get a PhD in Integrated Biomedical Science (focus: Cancer Biology) at The Ohio State University. She joined a laboratory focused on breast cancer research, and started volunteering at The James Cancer Hospital and with The Komen Foundation. She then completed postdoctoral studies at the University of Chicago, where she started to focus on the APC tumor suppressor and developing targeted therapies for breast cancer. In 2012, she was recruited to Indiana University School of Medicine – South Bend with an adjunct faculty position at the University of Notre Dame. Through these affiliations, she has been a member of both the Simon Cancer Center and the Harper Cancer Research Institute since 2012. Her laboratory is focused on the understanding of resistance to chemotherapy in breast cancer patients, specifically how the APC tumor suppressor impacts this process.
Bibliographic Information
Book Title: Resistance to Targeted Therapies in Breast Cancer
Editors: Jenifer R. Prosperi
Series Title: Resistance to Targeted Anti-Cancer Therapeutics
DOI: https://doi.org/10.1007/978-3-319-70142-4
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Hardcover ISBN: 978-3-319-70141-7Published: 13 December 2017
Softcover ISBN: 978-3-319-88891-0Published: 23 June 2018
eBook ISBN: 978-3-319-70142-4Published: 04 December 2017
Series ISSN: 2196-5501
Series E-ISSN: 2196-551X
Edition Number: 1
Number of Pages: XV, 184
Number of Illustrations: 12 b/w illustrations
Topics: Cancer Research