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Unresolved problems in Haemophilia

  • Book
  • © 1982

Overview

Editors:
  1. Charles D. Forbes

    1. University Department of Medicine, Glasgow, UK

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  2. Gordon D. O. Lowe

    1. University Department of Medicine, Glasgow, UK

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-x
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  2. Liver Disease in Haemophilia

    1. Front Matter

      Pages 1-4
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    2. The epidemiology of Factor VIII and IX associated hepatitis in the UK

      • Public Health Laboratory, Withington Hospital
      Pages 5-17

    3. Viruses causing hepatitis

      • C. H. Cameron
      Pages 19-25

    4. Clinical, immunological and histological aspects of non-A, non-B hepatitis in haemophiliacs

      • H. C. Thomas, M. Bamber, P. B. A. Kernoff
      Pages 27-37

    5. Liver biopsy in non-A, non-B hepatitis

      • P. J. Scheuer
      Pages 39-39

    6. Experience of liver disease in haemophilia

      • F. E. Preston, D. R. Triger, J. C. E. Underwood
      Pages 41-54

    7. The development of hepatitis B vaccines and antiviral therapy

      • C. R. Howard
      Pages 55-69

  4. Factor VIII — Structure, Function and Genetics

    1. Front Matter

      Pages 157-157
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    2. Factor VIII — structure and function

      • L. Hoyer
      Pages 159-172

    3. Factor VIIIC — immunology and activity

      • I. Peake
      Pages 173-182

    4. Genetics of Factor VIII

      • J. Graham
      Pages 183-201
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Keywords

About this book

These proceedings are of a symposium held jointly by the UK Haemophilia Centre Directors and the Royal College of Physicians and Surgeons of Glasgow. The purpose of the meeting was to highlight the growing areas of haemophilia care and research as they serve as a model for the study of other disorders. In particular a major section of these proceedings is devoted to the investigation of liver disease in haemophili- an area which offers unique opportunities for both basic, applied and clinical research. The second section considers modern treatment of bleeding disorders and the potential cost to society. With the advent of better standards of care, the requirements of plasma products have risen to such an extent that future predictions suggest a worldwide shortage may occur. The third section of the book discusses the detailed structure of the Factor VIII molecule and its sub-compon(!nts and also its functional and immunological characteristics. The availability of amniocentesis and its accuracy in predicting which factor is affected has produced new problems for genetic counselling. The fourth section is clinical and describes the experience of procedures in the Nuffield Department of Orthopaedics, Oxford. For all of us looking after such patients this remains the most important unsolved cI inical problem. C. D. Forbes G. D. O. Lowe vii List of Contributors Professor Charles Abildgaard, Dr. Geijlswijk, Department of Paediatrics, Department of Haematology, 4301 X Street, University Hospital, Sacramento, Utrecht, California 95817 The Netherlands Dr. L.

Editors and Affiliations

  • University Department of Medicine, Glasgow, UK

    Charles D. Forbes, Gordon D. O. Lowe

Bibliographic Information

  • Book Title: Unresolved problems in Haemophilia

  • Editors: Charles D. Forbes, Gordon D. O. Lowe

  • DOI: https://doi.org/10.1007/978-94-011-9764-9

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1982

  • Softcover ISBN: 978-0-85200-388-6Published: 31 January 1982

  • eBook ISBN: 978-94-011-9764-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: X, 245

  • Number of Illustrations: 12 b/w illustrations

  • Topics: Hematology

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