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Fundus Autofluorescence

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Retinal Angiography and Optical Coherence Tomography

Fundus spectrophotometric studies by Delori et al.1,2 have shown that fundus autofluorescence (FAF) in vivo is mainly derived from retinal pigment epithelium (RPE) lipofuscin. In the past, lipofuscin accumulation has been largely studied in vitro using fluorescence microscopic techniques.3–5 Excessive accumulation of lipofuscin represents a common pathogenetic pathway in various complex retinal diseases and is believed to precede photoreceptor degeneration.6–8

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Author information

Authors and Affiliations

  1. Denver Health Medical Center, USA

    Antonio P. Ciardella MD (Director of Ophthalmology, Associate Professor of Ophthalmology)

  2. University of Colorado Health Science Center, Denver, Colorado

    Antonio P. Ciardella MD (Director of Ophthalmology, Associate Professor of Ophthalmology)

  3. Eye Clinic University of Torino, Torino, Italy

    Chiara M. Eandi MD, PhD

Authors
  1. Antonio P. Ciardella MD
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  2. Chiara M. Eandi MD, PhD
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Editors and Affiliations

  1. Retina and Vitreous Service, Clinica Oftalmológica Centro Caracas, The Arevalo-Coutinho Foundation for Research in Ophthalmology, Caracas, Venezuela

    J. Fernando Arevalo MD, FACS (Professor and Chairman) (Professor and Chairman)

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Ciardella, A.P., Eandi, C.M. (2009). Fundus Autofluorescence. In: Arevalo, J.F. (eds) Retinal Angiography and Optical Coherence Tomography. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68987-6_24

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  • DOI: https://doi.org/10.1007/978-0-387-68987-6_24

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-68986-9

  • Online ISBN: 978-0-387-68987-6

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