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The Elastic Fiber

  • Chapter
Cell Biology of Extracellular Matrix

Abstract

With the development of higher organisms came the need for tissue flexibility and the necessity to withstand stretch. Several unrelated proteins have evolved to satisfy this requirement, including resilin in arthropods, abductin in molluscs, and elastin in the vertebrates (Sage and Gray, 1979). Phylogenetic studies have shown that elastin occurs only in vertebrates and arose first in cartilaginous fish where its appearance coincides with the achievement of a fully closed circulatory system. The occurrence of elastin in both primitive and modern sharks, and in chondrostean fishes suggests that the protein appeared in an early Devonian ancestor of all present-day fish, at some point after the divergence of the cyclostome and gnathostome lines (Sage, 1983).

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Authors and Affiliations

  1. Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA

    Robert P. Mecham

  2. Department of Medicine, Respiratory and Critical Care Division, Jewish Hospital at Washington University Medical Center, St. Louis, Missouri, 63110, USA

    Robert P. Mecham

  3. Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA

    John E. Heuser

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  1. Department of Anatomy and Cellular Biology, Harvard Medical School, Boston, Massachusetts, 02115, USA

    Elizabeth D. Hay

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Mecham, R.P., Heuser, J.E. (1991). The Elastic Fiber. In: Hay, E.D. (eds) Cell Biology of Extracellular Matrix. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3770-0_4

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  • DOI: https://doi.org/10.1007/978-1-4615-3770-0_4

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