Perianal Vegetations in a 1-Year-Old Child

Abstract

Condyloma Acuminatum (CA) is a kind of proliferative lesion caused by human papillomavirus infection. Most of the patients are young people aged 18–35 years old with sexual ability. The disease is mainly transmitted through sexual contact, but also through mother to child and indirect objects transmission. Genital and perianal are the most common occur sites of condyloma acuminatum. The skin lesions showed small and reddish papules at the beginning, then gradually increased, and the subjective symptoms is not pain or itching. Skin, mucosa and metaplasia squamous epithelium are susceptible to HPV infection. The exfoliated epithelium or keratin both with virus particles of patients enter the epithelial fissure of healthy people through the friction of genitalia. The virus particles lurk in the keratinocytes of the basal layer, and enter the nucleus with the replication of epidermis. When cells divide, the virus particles multiply and spread. Infants and young children do not have the ability and demand for sexual intercourse, and the main way of transmission of the disease is passive friction. This paper reports a case of infantile perianal condyloma acuminatum, deeply analyze the causes of the disease and the social ethical issues involved, and briefly review the relevant literature.