Abstract
In this chapter we present in vivo experiments with a new minimally invasive method of monitoring intracranial pressure (ICP). Strain gauge deformation sensors are externally glued onto the exposed skull. The signal from these sensors is amplified, filtered, and sent to a computer with appropriate software for analysis and data storage. Saline infusions into the spinal channel of rats were performed to produce ICP changes, and minimally invasive ICP and direct Codman intraparenchymal ICP were simultaneously acquired in six animals. The similarity between the invasive and minimally invasive methods in response to ICP increase was assessed using Pearson’s correlation coefficient. It demonstrated good agreement between the two measures < r > = 0.8 ± 0.2, with a range of 0.31–0.99.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Alperin NJ, Lee SH, Loth F, Raskin PB, Lichtor T (2000) Intracranial pressure: a method to measure intracranial elastance and pressure invasively by means of MR imaging: baboon and human study. Radiology 217:877–885
Czosnyka M, Pickard JD (2004) Monitoring and interpretation of intracranial pressure. J Neurol Neurosurg Psychiatry 75(6):813–821
Idro R, Marsh K, John CC, Newton CRJ (2010) Cerebral malaria; mechanisms of brain injury and strategies for improved neuro-cognitive outcome. Pediatr Res 68:267–274
Machado ABM (2004) Neuroanatomia funcional, 2nd edn. Editora Atheneu, São Paulo
Mascarenhas S, Vilela GHF, Carlotti C, Damiano LEG, Seluque W, Colli BO, Tanaka K (2012) New ICP minimally invasive method shows Monro-Kellie doctrine not valid. Acta Neurochir 114:117–120
Newton CRCJ, Hien TT, White N (2000) Cerebral malaria. J Neurol Neurosurg Psychiatry 69:433–441
Pitlyk PJ, Piantanida TP, Ploeger DW (1985) Noninvasive intracranial pressure monitoring. Neurosurgery 17:581–584
Acknowledgments
Conselho Nacional de Desenvolvimento e Pesquisa (CNPq), Fundação de Amparo a Pesquisa do Estado de São Paulo (FAPESP), Brazilian Ministry of Health Pan American Health Organization – World Health Organization (PAHO-WHO), and Sapra for financial support.
Conflict of Interest
ICM+ is a software program for brain monitoring in clinical/experimental neurosciences, licensed by Cambridge Enterprise Ltd (www.neurosurg.cam.ac.uk/icmplus). MC has an interest in part of the licensing fee. The remaining authors declare that they have no conflicts of interest.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Vilela, G.H.F. et al. (2016). Validation of a New Minimally Invasive Intracranial Pressure Monitoring Method by Direct Comparison with an Invasive Technique. In: Ang, BT. (eds) Intracranial Pressure and Brain Monitoring XV. Acta Neurochirurgica Supplement, vol 122. Springer, Cham. https://doi.org/10.1007/978-3-319-22533-3_19
Download citation
DOI: https://doi.org/10.1007/978-3-319-22533-3_19
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-22532-6
Online ISBN: 978-3-319-22533-3
eBook Packages: MedicineMedicine (R0)