Skip to main content
SpringerLink
Log in

Corneal Perforation in Herpes Zoster Ophthalmicus Caused by Eyelid Scarring With Exposure Keratitis

  • Conference paper
Herpetische Augenerkrankungen

Summary

We present four cases of corneal perforation in herpes zoster ophthalmicus. In all cases, corneal exposure, hypesthesia, and treatment with topical corticosteroids caused the perforation. Corneal perforation can occur without zoster keratouveitis. Vigorous early prophylaxis such as tarsorrhaphy, lubrication, and soft contact lenses can prevent these disasters.

Zusammenfassung

Wir berichten über vier Patienten mit einer Hornhaut-perforation nach Zoster ophthalmicus. In allen Fällen verursachten ein ungenügender Lidschluß mit Hornhaut-exposition, Hypaesthesie und lokale Steroidbehandlung diesen schweren Verlauf. Eine Hornhaut-perforation kann auch ohne Zoster-Keratouveitis eintreten. Nur mit energischen und frühzeitig einsetzenden Maßnahmen wie Tarsorrhaphie, Salbenabdeckung und weichen therapeutischen Kontaktlinsen kann man solch eine schwere Komplikation abwenden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Hybord A (1873) Du zona ophthalmique et des lesions oculaires qui s’y rattachent. Summarized in New York Medical Journal 17: 642 (from Paris-Adrien Delahaye, 1878, p 161)

    Google Scholar 

  2. Jeffries BJ (1873) Two cases of herpes zoster ophthalmicus destroying the eye. Trans Am Ophthalmol Soc 11: 73

    Google Scholar 

  3. Calhoun AW (1873) Herpes zoster ophthalmicus. Atlanta Medical and Surgical Journal 11: 188

    Google Scholar 

  4. Randolph RL (1901) Herpes zoster ophthalmicus resulting in loss of the eye. Arch Ophthalmol 30: 414

    Google Scholar 

  5. Edgerton AE (1945) Herpes zoster ophthalmiccus. Report of cases and review of literature. Arch Ophthalmol 34: 40–114

    Article  Google Scholar 

  6. Doden W (1960) Zoster ophthalmicus gan-graenosa mit Verlust des Augapfels. Klin Monatsbl Augenheilkd 136: 230

    CAS  Google Scholar 

  7. Blodi FC (1968) Ophthalmie zoster in malignant disease. Am J Ophthalmol 65: 686

    PubMed  CAS  Google Scholar 

  8. Sugar HS (1971) Herpetic keratouveitis: clinical experiences. Ann Ophthalmol 3: 335

    Google Scholar 

  9. Marsh RJ (1973) Herpes zoster keratitis. Trans Ophthalmol Soc UK 93: 181

    PubMed  CAS  Google Scholar 

  10. Marsh RJ (1976) Current management of ophthalmic herpes zoster. Trans Ophthalmol Soc UK 96: 334

    PubMed  CAS  Google Scholar 

  11. Pavan-Langston D (1975) Varicella zoster ophthalmicus. Int Ophthalmol Clin 15: 171

    Article  PubMed  CAS  Google Scholar 

  12. Duke-Elder S (1965) System of ophthalmology, Vol VIII. Diseases of the Outer Eye. Kimpton, London, p 340

    Google Scholar 

  13. Pavan-Langston D (1979) Ocular virus diseases. In: Galasso GJ, Merigan TC, Buchanan RA (eds) Antiviral agents and viral diseases of man., New York, p 274

    Google Scholar 

  14. Achard C (1924) Zona ophthalmique. Paris Med 51: 285

    Google Scholar 

  15. Wolfe E (1976) Anatomy of the eye and orbit, 7 ed. Saunders, Philadelphia, p 306

    Google Scholar 

  16. Head H, Campbell AW (1900) The pathology of herpes zoster and its bearing on sensory location. Brain 23: 353

    Article  Google Scholar 

  17. Naumann G, Gass JDM, Font RL (1968) Histopathology of herpes zoster ophthalmicus. Am J Ophthalmol 65: 533

    PubMed  CAS  Google Scholar 

  18. Zacks SI, LangfittTW, Elliott FA (1964) Herpetic neuritis. A light and electron microscopic study. Neurology 14: 744

    Google Scholar 

  19. Cavanagh HD, Colley A, Pihlaja DJ (1979) Persistent corneal epithelial defects. Int Ophthalmol Clin 19: 197

    PubMed  CAS  Google Scholar 

  20. Lemp MA (1979) Diagnosis and treatment of tear deficiencies. In: Wilson LA (ed) External diseases of the eye. Harper and Row, Hagerstown, p 143

    Google Scholar 

  21. Vachtenheim J, Grossman J (1963) Herpes zoster and steroid therapy. Br Med J 2: 622

    Article  Google Scholar 

  22. De Moragas JM, Kierland RR (1957) The outcome of patients with herpes zoster. Arch Dermatol 75: 193

    Article  Google Scholar 

  23. Wright ER, Winer LH (1961) Herpes zoster and malignancy. Arch Dermatol 84: 242

    Article  PubMed  CAS  Google Scholar 

  24. Williams HM, Diamond HD, CraverLF (1958) The pathogenesis and management of neurological complications in patients with malignant lymphomas and leukemia. Cancer 11: 76

    Article  PubMed  CAS  Google Scholar 

  25. Shanbrom E, Miller S, Haar H (1960) Herpes zoster in hematologic neoplasias: some unusual manifestations. Ann Intern Med 53: 523

    PubMed  CAS  Google Scholar 

  26. Merselis JG, Kay D, Hook EW (1964) Disseminated herpes zoster. A report of 17 cases. Arch Intern Med 113: 679

    Article  PubMed  Google Scholar 

  27. Rifkind D (1966) The activation of varicella zoster virus infections by immunosuppressive therapy. J Lab Clin Med 68: 463

    PubMed  CAS  Google Scholar 

  28. Sokal JE, Firat D (1965) Varicella zoster infection in Hodgkin’s disease: Clinical and epidemiological aspects. Am J Med 39: 452

    Google Scholar 

  29. Elliott FA (1964) Treatment of herpes zoster with high doses of prednisone. Lancet 2: 610

    Article  PubMed  CAS  Google Scholar 

  30. Sheie HG (1970) Herpes zoster ophthalmicus. Trans Ophthalmol Soc UK 90: 899

    Google Scholar 

  31. Stevens DA, Merigan TC (1972) Interferon, antibody, and other host factors in herpes zoster. J Clin Invest 51: 1170

    Article  PubMed  CAS  Google Scholar 

  32. Miller LH, Brunell PA (1970) Zoster, reinfection or activation of latent virus? Observation on the antibody response. Am J Med 49: 480

    Article  PubMed  CAS  Google Scholar 

  33. Berman M (1978) Regulation of collagenase. Therapeutic considerations. Trans Ophthalmol Soc UK 98: 397

    PubMed  CAS  Google Scholar 

  34. Kline LB, Jackson WB (1977) Herpes zoster conjunctival ulceration. Can J Ophthalmol 12: 66

    PubMed  CAS  Google Scholar 

  35. Mondino BJ, Brown SI, Mondzelewski JP (1978) Peripheral corneal ulcers with herpes zoster ophthalmicus. Am J Ophthalmol 86: 611

    PubMed  CAS  Google Scholar 

  36. Pavan-Langston DM, McCulley JP (1973) Herpes zoster dendritic keratitis. Arch Ophthalmol 89: 25

    Article  PubMed  CAS  Google Scholar 

  37. Hayashi S (1975) Study of herpes zoster keratitis, demonstration of virus particles in corneal scrapings. Acta Soc Ophthalmol Jpn 79: 542

    Google Scholar 

  38. Uchida Y, Kameyama K, Kaneko M, Inoue S, Yohda Y, Handa S (1974) Study on herpes zoster keratitis. Acta Soc Ophthalmol Jpn 78: 1073

    CAS  Google Scholar 

  39. Hogan MJ, Zimmerman LE (1962) Ophthalmic pathology. An atlas and text, 2 ed. Saunders, Philadelphia, p 298

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. California, USA

    G. O. Waring & M. B. Ekins

Authors
  1. G. O. Waring
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. B. Ekins
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Augenklinik der Universität Freiburg, Killianstr. 5, D-7800, Freiburg i.Br., Germany

    Rainer Sundmacher

Rights and permissions

Reprints and permissions

Copyright information

© 1981 J.F. Bergmann Verlag, München

About this paper

Cite this paper

Waring, G.O., Ekins, M.B. (1981). Corneal Perforation in Herpes Zoster Ophthalmicus Caused by Eyelid Scarring With Exposure Keratitis. In: Sundmacher, R. (eds) Herpetische Augenerkrankungen. Internationales Symposion der Deutschen Ophthalmologischen Gesellschaft vom 12. bis 14. April 1980 in Freiburg. J.F. Bergmann-Verlag. https://doi.org/10.1007/978-3-642-80499-1_79

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-80499-1_79

  • Publisher Name: J.F. Bergmann-Verlag

  • Print ISBN: 978-3-8070-0324-5

  • Online ISBN: 978-3-642-80499-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation