Abstract
Four years ago we postulated, on the basis of our observations of nearly 100 narcoleptics and those of other researchers, the existence of two types of narcolepsy. Primary narcolepsy was thought to be characterized by an early onset (in adolescence or the 3rd decade), a high prevalence of afflicted individuals in the family, and the absence of precipitating factors associated with the onset of the illness. Secondary narcolepsy was characterized by a late onset of narcoleptic symptoms, the absence of other afflicted members in the family, and the presence of possible precipitating factors like head trauma, CNS infectious diseases, affective disorders, or other factors such as shift work likely to disrupt the sleep-wake cycle.
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Montplaisir, J., Poirier, G. (1988). HLA in Narcolepsy in Canada. In: Honda, Y., Juji, T. (eds) HLA in Narcolepsy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83387-8_7
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DOI: https://doi.org/10.1007/978-3-642-83387-8_7
Publisher Name: Springer, Berlin, Heidelberg
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