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Methods, applications and concepts of metabolite profiling: Secondary metabolism

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Plant Systems Biology

Part of the book series: Experientia Supplementum ((EXS,volume 97))

Abstract

Plants manufacture a vast array of secondary metabolites/natural products for protection against biotic or abiotic environmental challenges. These compounds provide increased fitness due to their antimicrobial, anti-herbivory, and/or alleopathic activities. Secondary metabolites also serve fundamental roles as key signaling compounds in mutualistic interactions and plant development. Metabolic profiling and integrated functional genomics are advancing the understanding of these intriguing biosynthetic pathways and the response of these pathways to environmental challenges. This chapter provides an overview of the basic methods, select applications, and future directions of metabolic profiling of secondary metabolism. The emphasis of the application section includes the combination of primary and secondary metabolic profiling. The future directions section describes the need for increased chromatographic and mass resolution, as well as the inevitable need and benefit of spatially and temporally resolved metabolic profiling.

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Authors and Affiliations

  1. Plant Biology Division, The Samuel Roberts Noble Foundation, 2510 Sam Noble Parkway, Ardmore, OK, 73401, USA

    Lloyd W. Sumner, David V. Huhman, Ewa Urbanczyk-Wochniak & Zhentian Lei

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  1. Lloyd W. Sumner
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  2. David V. Huhman
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  3. Ewa Urbanczyk-Wochniak
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  4. Zhentian Lei
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Editors and Affiliations

  1. Institute of Plant Sciences, Swiss Federal Institute of Technology, ETH Zentrum, LFW E, 8092, ZĂĽrich, Switzerland

    Sacha Baginsky

  2. MPI for Molecular Plant Physiology, Am MĂĽhlenberg 1, 14476, Golm, Germany

    Alisdair R. Fernie

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Sumner, L.W., Huhman, D.V., Urbanczyk-Wochniak, E., Lei, Z. (2007). Methods, applications and concepts of metabolite profiling: Secondary metabolism. In: Baginsky, S., Fernie, A.R. (eds) Plant Systems Biology. Experientia Supplementum, vol 97. Birkhäuser Basel. https://doi.org/10.1007/978-3-7643-7439-6_9

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